Cystic lesions of anterior mediastinum: Case report

© 2020, University of Kragujevac, Faculty of Science. All rights reserved. Cystic lesions of the mediastinum are uncommon, comprising 12% to 18% of all primary mediastinal tumors and unless they attain a large size and cause compressive symptoms, these tumors are generally asymptomatic and are discovered incidentally upon radiologic investigation of some other condition. We present in this paper a case of cystic lesions of the mediastinum in a 70-year-old male patient who underwent a surgery for mediastinal mass removal. Histopathology report had shown it was the case of mature cystic teratoma of anterior mediastinum. Based on a review of the literature, as well as our experience, we conclude that best treatment for cystic lesions of anterior mediastinum is complete surgical resection if possible

Foreign body extraction through the rigid bronchoscopy

Introduction. Foreign body aspiration into tracheobronchial tree represents an urgent condition at high level of risk. Etiology is different, and this condition is typical for all ages with highest incidence in pediatric population. Case report. A successful foreign body removal (partial denture) in a 34-year old man was presented. Radiography and computerized tomography of the chest showed a foreign body localized at the level of the right bronchus including the right middle lobe bronchus. By the use of rigid bronchoscopy, a foreign body was visualized and mobilized from the segmental bronchus in the first act, and then completely extracted. Conclusion. Efficient diagnostics and extraction are imperative for the aspirated foreign body preventing life-threatening complications

Extraintestinal manifestations of the eye in patients with inflammatory bowel diseases

© 2017, Serbian Medical Society. All rights reserved. Extraintestinal manifestations of Crohn’s disease and ulcerative colitis were observed in almost half of the patients. They should be distinguished from secondary illnesses and complications. The most commonly affected organs are joints, skin, eyes, liver, gallbladder, urogenital and hematopoietic system. Eye manifestations are, although rare, an important form of morbidity, with possible blindness. The prevalence is higher in women and if the bowel disease is diagnosed at younger age, but lower than in children. Considering the great impact on the life quality, sometimes higher than gastrointestinal symptoms are, the goal is to show the importance of recognition and clinical and diagnostic approach to some ophthalmic entities. Symptomology of the most common changes, iritis, episcleritis and scleritis is nonspecific, and therefore the clinical evaluation is potentially underestimated both from the patient’s and from the doctor’s point of view. Ophthalmologic examination should be more frequent and an integral part of care for patients with inflammatory bowel disease. It is necessary to be well aware of the possible symptoms on the eye diseases, because they can precede inflammatory bowel disease. Treatment and adequate control of basic systemic disease contribute to the control of eye disease

Cystic Lesions of Anterior Mediastinum: Case Report

Cystic lesions of the mediastinum are uncommon, comprising 12% to 18% of all primary mediastinal tumors and unless they attain a large size and cause compressive symptoms, these tumors are generally asymptomatic and are discovered incidentally upon radiologic investigation of some other condition

The Collis Procedure and the Acquired Short Esophagus

One of the most intriguing problems in modern esophageal surgery is the acquired short esophagus. While some authors recognize this entity, others deny its existence. There is a consensus about types of the short esophagus, its etiology and pathophysiology. Definitive diagnosis can be established only intraoperatively. There are a few surgical procedures for this problem, and most frequently is used Collis gastroplasty with fundoplication. In this review we emphasize recent literature data and further perspectives of the Collis procedure

Breast Cancer and p16: Role in Proliferation, Malignant Transformation and Progression

The definition of new molecular biomarkers could provide a more reliable approach in predicting the prognosis of invasive breast cancers (IBC). The aim of this study is to analyze the expression of p16 protein in IBC, as well as its participation in malignant transformation. The study included 147 patients diagnosed with IBC. The presence of non-invasive lesions (NIL) was noted in each IBC and surrounding tissue. p16 expression was determined by reading the percentage of nuclear and/or cytoplasmic expression in epithelial cells of IBC and NIL, but also in stromal fibroblasts. Results showed that expression of p16 increases with the progression of cytological changes in the epithelium; it is significantly higher in IBC compared to NIL (p < 0.0005). Cytoplasmic p16 expression is more prevalent in IBC (76.6%), as opposed to nuclear staining, which is characteristic of most NIL (21.1%). There is a difference in p16 expression between different molecular subtypes of IBC (p = 0.025). In the group of p16 positive tumors, pronounced mononuclear infiltrates (p = 0.047) and increased expression of p16 in stromal fibroblasts (p = 0.044) were noted. In conclusion, p16 protein plays an important role in proliferation, malignant transformation, as well as in progression from NIL to IBC

Risk Factors For Development Of Acute Necrotizing Pancreatitis

Acute necrotizing pancreatitis (ANP) is a severe form of acute pancreatitis that is associated with high morbidity and mortality. Thus, an adequate initial treatment of patients who present with acute pancreatitis (AP) based on correct interpretation of early detected laboratory and clinical abnormalities may have a significant positive impact on the disease course