Comparative Pharmaceutico - Analytical Study of Kushthaghna Mahakashaya and its Ghanavati w.s.r. to evaluate its shelf life

In this present era of utilization of active principles as a medicine the basic formulations of Bhaishajya Kalpana remain a main source for modern research. The basic formulations are described as Panchavidha Kashaya Kalpanas. Out of these Kashaya Kalpanas, Kwatha Kalpana is an important formulation which is having more potency after Swarasa and Kalka Kalpana. Kashaya has very short shelf life (Saveeryatavadhi). These Kashayas cannot be preserved for longer period. These have to be prepared fresh every day and also the method of preparation is time consuming. Rasakriya (Ghana) is a type of formulation where in the active components can be stored for more days i.e. 3 years (D&C act 161B, w.e.f. 1st April 10). Converting this Kashaya in to Ghana form and then into Ghanavati form may increase the shelf life of the formulation. Along with this it will give a proper shape and dose for the easy administration of medicament. Hence the present research was planned to convert Kushthaghna Mahakashaya Kwatha into Kushthaghna Mahakashaya Ghanavati using standard operating procedure to potentiate active principle in it, and to evaluate shelf life of Kushthaghna Mahakashaya Ghanavati

To study the efficacy of Makarasana as an Agnivardhana Karma

Generally in young age, keeps on doing Mithya Aahara and Vihara which leads to Agnidusthi and which become cause of various diseases. As they work restless, their sedentary habits and stress full lifestyle. They are ought to do Vishamashan, Krodha etc., due to their lifestyle. This type of lifestyle leads to Agnidushti and which becomes cause of various diseases. 80 volunteers of age group 20-40 years were selected for the study. They underwent for clinical study on the basis of number of Lakshanas present. These were taken as subjective parameter and which were Samanya and Vishesh Lakshanas. Those were Arochaka, Vidagdha Udgara, Vishtambha, Aadhmana, Anga-Marda, Atijrumbha, Shirshula, Guru Gatrata, Utklesh. Jarana Kala and Abhyavaharan Shakti were objective parameters, as these two are important to assess Agni of a person. For Jarana Kala gradation was done on the basis of hours of time taken to show Laghuta and Kshuda Bodha, because these are Jeerna Aahara Lakshanas. For Abhyavaran Shakti gradation was done on the basis of quantity of food. To assess Agnivardhana, specific diet chart was prepared by considering their daily requirement of calorie. Volunteers were advised to do three Avartana of Makarasana in the morning; Significant changes were seen in Abhyavaharana Shakti in both groups. 56.7% relief in group A and 72% relief were seen. There were significant changes seen in Jaran Kala in both groups. 54.9% relief in Group A and 74% relief in Group B

Study of Aushadh Sevan Kala in Kaphaja Kasa Vyadhi using Nagaradi Yoga w.s.r. to Grasantar Kala

The present study entitled ‘Study of Aushadha Sevana Kala in Kaphaj Kasa Vyadhi using Nagaradi Yoga with special reference to ‘Grasantar Kala’. Here Clinical study regarding “Kaphaj Kasa” Vyadhi was carried with the help of “Nagaradi Yoga” administered in Grasantar Kala in Group A and at Adhobhakta Kala in Group B 32 patients in each group have been studied with treatment and follow up after each 3 days upto 15 days. Clinical assessment of the patients was done by using criteria regarding Kasa included parameter like no. of Kasa Vega, Kapha Nishtivana, Aruchi, Agnimandya, Chhardi, Utklesha, Gaurava and Peenas. Assessment was done on the basis of scoring pattern designed for them. Asyamadhurya, Kaphapurna Deha, Praliptata, Sashakta Vaishamya and Lomharsha was not observed in any of the patients in this study in any of the group. As data was not available on the above said symptoms, statistical analysis of the symptoms is not needful. When drug was administered at Grasantara Kala more percentage of improvement is observed regarding almost all parameters showed in observation and results. So, it can be statistically concluded that drug administered in Grasantara Bheshaj Kala i.e. 95.84% shows maximum result in Kaphaja Kasa Vyadhi than Adhobhakta Kala i.e. 82.51%