17 research outputs found

    THEME OF 'ALIENATION' AS PROJECTED THROUGH THE CHARACTER – PORTRAYAL OF JIMMY PORTER IN JOHN OSBORNE'S LOOK BACK IN ANGER: AN APPRAISAL

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    This article, at the outset, lays focus on the theme of alienation, internal conflict and hostility experienced by Jimmy Porter in John Osborne’s play Look Back in Anger by examining how the character, Jimmy is furious with life, friends and his wife, alienating himself from the society, religion and women. It concludes, by stating that of all the modern dramatists, John Osborne has been gifted with the credit of dramatizing the insecurity and alienation felt by the younger generation by effectively picturing the loneliness of the central character Jimmy Porter in Look Back in Anger

    Khushwant Singh as an Adept in Picturizing both the Positive and Negative Images of Sikhism in his Fiction: A Brief Note

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    This paper is an attempt not only to project Khushwant Singh as one of the most distinguished writers in the field of contemporary Indian English fiction but also to show him as an adept in picturizing both the positive and negative images of Sikhism rather effectively in his fictional world, bringing home the point that as a brilliant novelist, story writer, historian and distinguished journalist, his literary achievements are far-ranging through publication of his two novels namely A Train to Pakistan and I Shall Not Hear the Nightingale as the finest realistic novels of Post-War-II of English fiction. It beautifully analyses Khushwant Singh’s literary and fictional art which gets deep rooted in the Punjabi soil and Sikh religion and his genuine passion and concern for his community and his healthy attachment to Sikhism in his fictional world

    The Modern Elegy both in English and Tamil as Taking a Limited Scale to Mean a Song of Lamentation: A Brief Note

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    This paper purports to define an elegy as a formal and sustained poem of lament for the death of a poem making references to the poems of the notable poets like Tennyson, Auden, Gray in English and Kannadasan, Mudiarasan’s Irangar Pakkal in Tamil and shows how the elegiac poems by English and Tamil poets have line of similarity in treatment of theme and content making it clear that in the modern elegies both in English and Tamil, the term ‘elegy’ has taken a limited scale meaning ‘a song of lamentation’ giving vent to philosophical elements and notes as seen rather richly in Auden’s In Memory of W.B. Yeats and Mudiarasan and Kannadasan’s Irangar Pakkal

    PROJECTION OF VEDANTIC THOUGHTS AND RELIGIOUS OVERTONES IN ROBERT BROWNING'S POETICAL WORKS: A BRIEF ANALYSIS

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    This paper is an attempt to project Robert Browning as one of the greatest Victorian poets who took the art and vacation of the poet with high seriousness, making poetry as something closely related to life and its problems with no faith in the theory of ‘Art for Art’s sake’ and to show to the public such a view of the poet that poetry and art should be intimately in touch with reality and life with his special focus on defining poetry as nothing but an instrument for unfolding the souls of individuals in all their complex aspects and the purpose of poetry and art was neither social propaganda nor political reform but study of human soul in all its diverse aspects. It neatly examines how Browning considered the poet as a sage and a teacher bent upon the task of bettering humanity by his noble message and philosophic thought coupled with religious and vedantic thoughts – incorporated in his poetry

    PROJECTION OF FEMINIST ELEMENTS IN THE FICTIONAL WORLD OF JANE AUSTEN AND GEORGE ELIOT: A NOTE

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    This article is nothing but a critical evaluation for renowned writers like Jane Austen and George Eliot and the Feminist elements highlighted in their works with their feminine and defiant tone of expression, they left their indelible imprint on the annals of English fiction. In the light of feminist critical theory, it can be the proved that both the writers explored the unexplored sense of agony and complex solitude of women character. This article also throws light on the characters of both the writers, who have developed their self – identity with an optimistic prospect

    Protein docking prediction using predicted protein-protein interface

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    <p>Abstract</p> <p>Background</p> <p>Many important cellular processes are carried out by protein complexes. To provide physical pictures of interacting proteins, many computational protein-protein prediction methods have been developed in the past. However, it is still difficult to identify the correct docking complex structure within top ranks among alternative conformations.</p> <p>Results</p> <p>We present a novel protein docking algorithm that utilizes imperfect protein-protein binding interface prediction for guiding protein docking. Since the accuracy of protein binding site prediction varies depending on cases, the challenge is to develop a method which does not deteriorate but improves docking results by using a binding site prediction which may not be 100% accurate. The algorithm, named PI-LZerD (using Predicted Interface with Local 3D Zernike descriptor-based Docking algorithm), is based on a pair wise protein docking prediction algorithm, LZerD, which we have developed earlier. PI-LZerD starts from performing docking prediction using the provided protein-protein binding interface prediction as constraints, which is followed by the second round of docking with updated docking interface information to further improve docking conformation. Benchmark results on bound and unbound cases show that PI-LZerD consistently improves the docking prediction accuracy as compared with docking without using binding site prediction or using the binding site prediction as post-filtering.</p> <p>Conclusion</p> <p>We have developed PI-LZerD, a pairwise docking algorithm, which uses imperfect protein-protein binding interface prediction to improve docking accuracy. PI-LZerD consistently showed better prediction accuracy over alternative methods in the series of benchmark experiments including docking using actual docking interface site predictions as well as unbound docking cases.</p

    Author Correction: Federated learning enables big data for rare cancer boundary detection.

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    Atherosclerosis and Alzheimer - diseases with a common cause? Inflammation, oxysterols, vasculature

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