A Biochemical Approach to Understand the Concept of Snigdha Guna of Ghee and Ruksha Guna of Terminalia arjuna on Behaviour of 3T3-L1 Cell Line with Respect to Adipocytic and Anti-Adipocytic Activity : In Vitro

Ayurvedic medicine is a system of traditional medicine native to India. Ayurveda is based on peculiar fundamental principles like Shatpadarth, Tridosha Theory, Panchamahabhuta Theory, Prakriti, Ojas, Dhatu, Mala, Agni, Manas, and Atma etc. The concepts of Ayurveda are expressed with Gunas. The increased elements are treated by opposite Guna. In support of the above concept, an experimental study on the 3T3-L1 cell line is carried out for examine the adipocytic and anti adipocytic activity of Snigdha and Ruksha Guna respectively. The results were assessed with the help of evaluation of sublethal concentration by using XTT assay and lipid assay. The aim of basic research in Ayurveda through bioscience is to explore scientific innovation and opportunities in fundamental concept of Ayurveda. Fundamental research needs to be done to highlight the concept of gurvadi guna through the in vitro study

Prospects of Ayurveda through Cell Line

Ayurveda is a science of life with a holistic approach to health and personalized medicine. It is a system of traditional medicine developed during antiquity and the medicinal period and as such as comparable to modern system of medicine. Ayurveda gives us a model to look at each individual as a unique make up of Tridosha and to thereby design treatment protocols. Unfortunately, due to lack of scientific validation in various concepts like Tridosha, Prakruti, Mahabhuta, Guna and its affect on body. Hence evidence-based research as highly needed for global recognition and acceptance of Ayurveda, which need further advancements in vitro study. The present review highlights to improve the fundamental principles, drugs, pharmaceuticals and clinical research in Ayurveda through cell line study. In vitro studies permit a species-specific, simpler, convenient and more detailed analysis that can be done with the whole organism. This attempt will certainly encourage to researchers to work on cell line for the development and promotion of Ayurveda