Biosorption Study of Pb(II) Ions onto Treated Eupatorium adinoforum (AEA) and Acer Oblongum (AAO): Thermodynamic and Equilibrium Studies

In the present study, dried activated biomass of Eupatorium adinoforum (AEA) and Acer oblongum (AAO) used for removal of Pb (II) from synthetic wastewater. The batch operation was conducted with effect of variation of contact time, biosorbent dose, pH, concentration of metal ions and temperature on biosorption of metal ions on biosorbent. Maximum adsorption was recorded for initial metal ion concentration of 10 mg/l, biosorbent dose of 2.5 gm, at pH 5 with 105 minutes of contact time for activated AEA and AAO biomass. The adsorption equilibrium conditions were well described by Langmuir, Freundlich and Temkin isotherm models. The Langmuir isotherm model has provided a better fit with the experimental data in comparison to that of Freundlich and Temkin isotherm models. Thermodynamic data suggest that the bisorption process was spontaneous, feasible and endothermic. The values of thermodynamic parameters suggest that the biosorption process was spontaneous, feasible and endothermic. The kinetics of the biosorption for the reaction mechanism and types of biosorption process onto activated AEA and AAO biosorbent were also discussed

From Evidence to Practice: Denosumab in Osteoporosis and Joint Health

Osteoporosis and osteopenia are prevalent conditions in India, particularly among postmenopausal women and the elderly,leading to increased fracture risks and morbidity. Denosumab, a monoclonal antibody, demonstrates superior efficacyover other treatments in reducing fracture risk and enhancing bone mineral density (BMD). Clinical trials highlight itseffectiveness in preventing periprosthetic bone loss, improving implant stability, and mitigating femoral head collapse invarious conditions; combination therapies involving denosumab further amplify BMD gains and reduce fracture risk. Thearticle reviews the efficacy and safety of denosumab in managing osteoporosis, joint replacement therapy, and avascularnecrosis based on a review of clinical evidence and studies. Denosumab emerges as a cornerstone therapy for osteoporosismanagement, offering multifaceted benefits in fracture prevention, joint replacement therapy, and avascular necrosis