Regenerative fuel cell combines high efficiency with low cost

Hydrogen/oxygen regenerative fuel cell stores electrical energy efficiently and inexpensively. The fuel cell has a high energy-to-weight ratio, and is adapted for a large number of cycles with deep discharge

Anhedonia predicts adverse cardiac events in people with acute coronary syndromes

Anhedonia predicts adverse cardiac events in people with acute coronary syndrome

Internet motives of users in the United States, United Kingdom, Australia, and Korea: a cross-cultural replication of the WMI

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The new open access journal on health psychology and behavioral medicine: why do we need it?

On behalf of the editorial board, it is our pleasure to introduce Health Psychology and Behavioral Medicine: an Open Access Journal (HPBM), which we hope will become a leading international journal in these areas. HPBM will be interdisciplinary and global in scope, offering studies in a wide range of forms including systematic and critical reviews, meta-analyses, ethnographic and qualitative studies, quantitative studies, program evaluation, policy studies, case studies, and research protocols. Individually and in combination, these publications will contribute to the development and integration of psychosocial, behavioral, and biomedical knowledge to promote and maintain health, to prevent, treat, and manage physical and psychological illness, and to identify etiological and diagnostic correlates of health and illness. Discrete but related topics including assessment, prevention, diagnosis, treatment, prognosis, and rehabilitation that contribute to health will be featured. The need for this new journal stems from both recent developments in the fields of health psychology and behavioral medicine, and the recent revolutionary movement of academic publishing into online dissemination

Optical IP switching a solution to dynamic lightpath establishment in disaggregated network architectures

The landscape of the telecommunications environment is constantly evolving; in terms of architecture and increasing data-rate. Ensuring that routing decisions are taken at the lowest possible layer offers the possibility of greatest data throughput. We propose using wavelengths in a DWDM scheme as dedicated channels that bypass the routing lookup in a router. The future trend of telecommunications industry is, however, toward larger numbers of interlinked competing operator networks. This in turn means there is a lack of a unified control plane to allow current networks to dynamically provision optical paths. This paper will report on the concept of optical IP switching. This concept seeks to address optical control plane issues in disaggregated networks while providing a means to dynamically provision optical paths to cater for large data flows

Longitudinal modelling of theory-based depressive vulnerabilities, depression trajectories and poor outcomes post-ACS

Background: Depression heterogeneity has hampered development of adequate prognostic models. Therefore, more homogeneous clinical entities (e.g. dimensions, subtypes) have been developed, but their differentiating potential is limited because neither captures all relevant variation across persons, symptoms and time. To address this, three-mode Principal Component Analysis (3MPCA) was previously applied to capture person-, symptom- and time-level variation in a single model (Monden et al., 2015). This study evaluated the added prognostic value of such an integrated model for longer-term depression outcomes. Methods: The Beck Depression Inventory (BDI) was administered quarterly for two years to major depressive disorder outpatients participating in a randomized controlled trial. A previously developed 3MPCA model decomposed the data into 2 symptom-components (‘somatic-affective’, ‘cognitive’), 2 time-components (‘recovering’, ‘persisting’) and 3 person-components (‘severe non-persisting depression’, ‘somatic depression’ and ‘cognitive depression’). The predictive value of the 3MPCA model for BDI scores at 3-year (n¼136) and 11-year follow-up (n¼145) was compared with traditional latent variable models and traditional prognostic factors (e.g. baseline BDI component scores, personality). Results: 3MPCA components predicted 41% and 36% of the BDI variance at 3- and 11-year follow-up, respectively. A latent class model, growth mixture model and other known prognostic variables predicted 4–32% and 3–24% of the BDI variance at 3- and 11-year follow-up, respectively. Limitations: Only primary care patients were included. There was no independent validation sample. Conclusion: Accounting for depression heterogeneity at the person-, symptom- and time-level improves longer-term predictions of depression severity, underlining the potential of this approach for developing better prognostic models

Transarterial Embolization of Angiomyolipoma - A Systematic Review.

INTRODUCTION: Transarterial embolization (TAE) is increasingly used in the management of renal angiomyolipoma (AML). The level of evidence establishing the safety and efficacy of TAE has not increased in parallel. MATERIALS AND METHODS: Using the MOOSE criteria, a systematic review of transarterial embolization of angiomyolipoma was performed to establish procedural safety and efficacy. MEDLINE PubMed search revealed 1739 publications, of which 31 studies met eligibility criteria. RESULTS: 524 cases of TAE of AML were included. Self-limiting post-embolization syndrome occurred following 35.9%. Further morbidity occurred in 6.9%. No procedural mortality was reported. At a mean follow-up period of 39 months, mean size reduction was 3.4 cm (-38.3% of AML diameter). Unplanned repeat embolization or surgery was required in 20.9% during this period. The most frequent indications for repeat procedures include angiomyolipoma revascularization (30.0%), unchanged or increasing size (22.6%), refractory or recurring symptoms (16.7%), and representation with acute retroperitoneal hemorrhage (14.3%). A combination of two or more embolic agents was used in 46.8%, ethanol monotherapy in 41.7%, coil monotherapy in 6.2%, and foam or microparticle monotherapy in 5.2%. CONCLUSIONS: Transarterial embolization of angiomyolipoma demonstrates low rates of mortality and serious complications. Retreatment rates and size reduction at a mean follow-up duration of 39 months are presented. Longitudinal data assessing long-term size reduction and retreatment rates are lacking, recommendations guiding the indications for transarterial embolization and clear follow-up require further longitudinal data

Differential Predictive Value of Depressive Versus Anxiety Symptoms in the Prediction of 8-Year Mortality After Acute Coronary Syndrome.

ObjectiveBoth depression and anxiety have been associated with poor prognosis in patients with acute coronary syndrome (ACS). However, certain symptoms and how they are measured may be more important than others. We investigated three different scales to determine their predictive validity.MethodsPatients with ACS (N = 598) completed either the Hospital Anxiety and Depression Scales (HADS-A, HADS-D; n = 316) or the Beck Depression Inventory-Fast Screen (n = 282). Their all-cause mortality status was assessed at 8 years.ResultsDuring follow-up, 20% (121/598) of participants died. Cox proportional hazards modeling showed that the HADS-D was predictive of mortality (hazard ratio [HR] = 1.11, 95% confidence interval [CI] = 1.04-1.19), and this association remained significant after adjustment for major clinical/demographic factors, whereas the HADS-A (HR = 0.96, 95% CI = 0.85-1.09) and the Beck Depression Inventory-Fast Screen (HR = 0.99, 95% CI = 0.91-1.08) were not. The following depression items from the HADS-D predicted mortality: \u22I still enjoy the things I used to enjoy\u22 (HR = 1.38, 95% CI = 1.05-1.82), \u22I can laugh and see the funny side of things\u22 (HR = 1.48, 95% CI = 1.11-1.96), \u22I feel as if I am slowed down\u22 (HR = 1.66, 95% CI = 1.24-2.22), and \u22I look forward with enjoyment to things\u22 (HR = 1.36, 95% CI = 1.08-1.72).ConclusionsDepressive symptoms related to lack of enjoyment or pleasure and physical or cognitive slowing, as measured by the HADS-D, predicted all-cause mortality at 8 years ACS patients, whereas other depressive and anxiety symptoms did not. Whether symptoms of distress predict prognosis in ACS seems to be dependent on the measures and items used