Social Stigma and Sexual Minorities’ Romantic Relationship Functioning: A Meta-Analytic Review

PublishedArticleThis is the author accepted manuscript. The final version is available from SAGE Publications via the DOI in this record.To bolster knowledge of determinants of relationship functioning among sexual minorities, the current meta-analysis aimed to quantitatively review evidence for the association between social stigma and relationship functioning as well as examine potential moderators. Thirty-five studies were identified, including 130 effect sizes (39 independent; N = 10,745). Across studies, evidence was found for a small but significant inverse association between social stigma and relationship functioning. Furthermore, this association was moderated by stigma type (with more deleterious associations for internalized relative to perceived stigma) and dimension of relationship functioning (with more deleterious associations for affective relative to cognitive and negative relative to positive). Evidence for demographic moderators (region, sex, race, age) was generally mixed although important limitations related to unique characteristics of study samples are discussed. We conclude by highlighting the importance of social stigma for relationship functioning and point toward directions for future research and policy action.The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: David Matthew Doyle is now a postdoctoral fellow in the Department of Epidemiology at Columbia University, supported by training grant, T32MH13043, from the National Institute of Mental Health

Love on the margins: The effects of social stigma and relationship length on romantic relationship quality

PublishedArticleThis is the author accepted manuscript. The final version is available from SAGE Publications via the DOI in this record.National data on romantic relationships reveal a prominent gap between members of devalued and dominant groups in the United States, with devalued group members experiencing less positive relationship outcomes. However, little research examines how social stigma affects relationship quality for members of devalued groups and moderating factors have generally not been explored in the literature. In the current studies, we experimentally examined the effects of social stigma on relationship quality among women (Study 1) and African Americans (Study 2) as well as whether these effects differed based upon relationship length (Studies 1 and 2). Results showed that individuals involved in shorter relationships reported lesser relationship quality after social stigma was made salient, while those involved in longer relationships reported somewhat greater relationship quality after social stigma was made salient. Implications for future research on social stigma and relationship quality as well as moderating factors are discussed.The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Louisiana Board of Regents Grant (RA-547265) awarded to Lisa Molix

Stigma salience increases loneliness among ethnic minorities

This is the final version. Available on open access from Wiley via the DOI in this recordData availability statement: The datasets generated during the current study are available from the corresponding author upon reasonable request.Research shows that ethnic minorities are at increased risk of loneliness compared to the general population of the United Kingdom. We hypothesized that stigma salience increases loneliness among ethnic minorities, conducting two experimental studies with ethnic minorities (Study 1: N = 134, Study 2: N = 267) in which participants were randomly assigned to a stigma salience (recalling a personal experience of discrimination based upon ethnicity) or control condition (recalling a past meal in Study 1 and the experience of reading a book in Study 2). Across these two studies, we demonstrated that stigma salience consistently increased selfreported loneliness relative to the control conditions. Study 1 additionally showed evidence for an indirect effect of stigma salience on loneliness through feelings of anxiety. Study 2 replicated the effect of self-relevant (but not non-self-relevant) stigma salience on loneliness and provided suggestive evidence for a more specific indirect effect through identity-related social anxiety.European Unio

Reconciling associations between minority stress and sexual minority romantic relationship functioning

This is the final version. Available on open access from Frontiers Media via the DOI in this record. Cao et al. (2017) conducted a meta-analysis of the association between sexual minority stress and relationship well-being. Having published a similar meta-analysis (Doyle and Molix, 2015b), we were struck by a number of important similarities as well as critical differences in these two reviews, as other authors working on minority stress and sexual minority romantic relationship functioning have also been recently (e.g., Ballester et al., 2021; Vale and Bisconti, 2021). Here we aim to reconcile discrepant findings with regard to conceptual and methodological differences between the two reviews. Additionally, we aim to contribute to a broader discussion of understanding overlapping meta-analytic reviews (Siontis et al., 2013; Helfer et al., 2015). In order to integrate findings from these two reviews, for illustrative purposes we began by conducting a second-order meta-analysis using the psychmeta package in R (Dahlke and Wiernik, 2018). For reasons discussed in detail later, we conducted a “bare bones” second-order meta-analysis using uncorrected first-order meta-analysis estimates weighted by the number of primary studies included (Schmidt and Oh, 2013), shown in Table 1. Overall, the combined estimate of the effect of minority stress on sexual minority relationship functioning across these two meta-analyses was small but statistically significant, r = −0.144, 95% CI (−0.157, −0.132), echoing the importance of understanding minority stress processes for research on sexual minority romantic relationships. We continue to refer to the results of our “bare bones” second-order meta-analysis as we discuss similarities and differences in the two reports

Toward a more relational model of sexual minority identity concealment

This is the final version. Available from Springer via the DOI in this record.

Sexual orientation, disclosure, and cardiovascular stress reactivity

This is the author accepted manuscript. The final version is available from Taylor & Francis (Routledge) via the DOI in this record.Stigma may strain the heart health of lesbian, gay, and bisexual (LGB) individuals. To date, however, LGB-related differences in cardiovascular diagnosis, risk factors, and basal biomarkers are inconsistently reported. Using a laboratory-based stress paradigm, the current study assessed whether cardiovascular stress reactivity differs as a function of sexual orientation and disclosure status (‘coming out’) in a sample of healthy young LGB and heterosexual adults. Eighty-seven participants aged 18 to 45 (M = 24.61 ± 0.61 SE) identifying as LGB and heterosexual (47%) were exposed to the Trier Social Stress Test, a well-validated laboratory stressor involving public speaking and mental arithmetic. Throughout a two-hour session, ambulatory recordings for heart rate and blood pressure were collected. Self-report questionnaires were also administered to assess psychosocial and demographic variables. Gay/bisexual men showed higher heart rate and lesbian/bisexual women showed marginally higher mean arterial blood pressure in response to a stressor, compared to sex- and age-matched heterosexuals. No significant differences emerged when comparing LGB individuals who had completely disclosed and those that had not completely disclosed their sexual orientation to family and friends. Compared to heterosexuals, heart rate is higher among gay/bisexual men and blood pressure is marginally higher among lesbian/bisexual women, when exposed to a laboratory-based stressor. These preliminary findings contribute to a small literature on sexual orientation differences in stress reactive biomarkers that requires further exploration.Canadian Institutes of Health ResearchInstitute of Aging of the Canadian Institutes of Health Researc

Social relationship experiences of transgender people and their relational partners: A meta-synthesis

This is the final version. Available on open access from Elsevier via the DOI in this recordRationale: Social relationships are important in bolstering health and well-being for everyone in the general population. For transgender people, strong supportive social relationships may be paramount to their overall health and well-being due to their marginalised status in society. Objective: This review aimed to investigate what is currently known about social relationship experiences of transgender people and their relational partners (e.g., family members, romantic partners). Method: Thirty-nine qualitative papers were extracted from Web of Science, Scopus, Cochrane, and PubMed that related to social relationships of transgender people. These papers were analysed via a qualitative meta-synthesis. Results: Forty-nine second order themes were identified, initially organised into relational partner clusters (e.g., family, friends, work colleagues) for specific phenomena, then these were synthesized into five overarching conceptual themes: (1) Development of relationships through transition and beyond, (2) Coping strategies of transgender people and their relational partners, (3) Reciprocal support in social relationships, (4) Stigma enacted and ameliorated interpersonally, and (5) Influence of stigma on social health and well-being. Discussion and conclusions: These overarching themes show the potential characteristics that assist in the health-buffering role of social relationships for transgender people and their relational partners. Of particular note, stigma was reported as a common negative experience by transgender people and their relational partners, and open communicative social relationships had positive effects on self-conceptualisations of identity, which were inferred to protect against the damaging effects of stigma. We discuss the various implications and applications of this meta-synthesis to future research and clinical settings as well as how it can inform healthcare policy to support transgender people.Devon Partnership NHS Trus

Identity-Related Factors Protect Well-Being against Stigma for Transgender and Gender Non-Conforming People

This is the final version. Available on open access from Springer via the DOI in this recordAvailability of data and material: The materials and anonymized data for this study are available upon request to the corresponding author.Code availability: The code for analyses conducted in this work are available upon request to the corresponding author.Relatively little is known about identity-related resilience factors associated with well-being among transgender and gender non-conforming (TGNC) people. Drawing upon theory on stigma-related stress and resilience and work examining group identification as a buffer against discrimination, the aim of the current study was to model perceived discrimination, transgender identification, and gender identity affirmation as predictors of well-being for TGNC people. We also tested whether the positive association between gender identity affirmation and well-being might be explained by the benefits affirmation has for individual self-concept clarity. Participants were 105 TGNC individuals (42% transgender male, 39% transgender female, 19% other gender non-conforming [e.g., non-binary]) recruited through online forums and support groups in the United Kingdom and North America who completed an online survey including self-report measures of key constructs. Results from structural equation models demonstrated that: (1) experiences of discrimination were associated with lower well-being overall, but having a stronger transgender identity moderated this association; (2) after adjustment for discrimination and transgender identification, experiences of gender identity affirmation were independently associated with greater well-being for TGNC people. Secondary analyses demonstrated that gender identity affirmation was linked to well-being through reinforcing a strong, internalized sense of clarity about individual self-concept. Results are discussed in terms of the implications for TGNC health and well-being, particularly with regards to the need for supportive, identity-affirming social environments.University of Exete

Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study.

Antimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial-susceptibility testing (AST). As the implementation costs and technical barriers fall, whole-genome sequencing (WGS) has emerged as a 'one-stop' test for epidemiological and predictive AST results. Few published comparisons exist for the myriad analytical pipelines used for predicting AMR. To address this, we performed an inter-laboratory study providing sets of participating researchers with identical short-read WGS data from clinical isolates, allowing us to assess the reproducibility of the bioinformatic prediction of AMR between participants, and identify problem cases and factors that lead to discordant results. We produced ten WGS datasets of varying quality from cultured carbapenem-resistant organisms obtained from clinical samples sequenced on either an Illumina NextSeq or HiSeq instrument. Nine participating teams ('participants') were provided these sequence data without any other contextual information. Each participant used their choice of pipeline to determine the species, the presence of resistance-associated genes, and to predict susceptibility or resistance to amikacin, gentamicin, ciprofloxacin and cefotaxime. We found participants predicted different numbers of AMR-associated genes and different gene variants from the same clinical samples. The quality of the sequence data, choice of bioinformatic pipeline and interpretation of the results all contributed to discordance between participants. Although much of the inaccurate gene variant annotation did not affect genotypic resistance predictions, we observed low specificity when compared to phenotypic AST results, but this improved in samples with higher read depths. Had the results been used to predict AST and guide treatment, a different antibiotic would have been recommended for each isolate by at least one participant. These challenges, at the final analytical stage of using WGS to predict AMR, suggest the need for refinements when using this technology in clinical settings. Comprehensive public resistance sequence databases, full recommendations on sequence data quality and standardization in the comparisons between genotype and resistance phenotypes will all play a fundamental role in the successful implementation of AST prediction using WGS in clinical microbiology laboratories

Prehistory of Transit Searches

Nowadays the more powerful method to detect extrasolar planets is the transit method. We review the planet transits which were anticipated, searched, and the first ones which were observed all through history. Indeed transits of planets in front of their star were first investigated and studied in the solar system. The first observations of sunspots were sometimes mistaken for transits of unknown planets. The first scientific observation and study of a transit in the solar system was the observation of Mercury transit by Pierre Gassendi in 1631. Because observations of Venus transits could give a way to determine the distance Sun-Earth, transits of Venus were overwhelmingly observed. Some objects which actually do not exist were searched by their hypothetical transits on the Sun, as some examples a Venus satellite and an infra-mercurial planet. We evoke the possibly first use of the hypothesis of an exoplanet transit to explain some periodic variations of the luminosity of a star, namely the star Algol, during the eighteen century. Then we review the predictions of detection of exoplanets by their transits, those predictions being sometimes ancient, and made by astronomers as well as popular science writers. However, these very interesting predictions were never published in peer-reviewed journals specialized in astronomical discoveries and results. A possible transit of the planet beta Pic b was observed in 1981. Shall we see another transit expected for the same planet during 2018? Today, some studies of transits which are connected to hypothetical extraterrestrial civilisations are published in astronomical refereed journals. Some studies which would be classified not long ago as science fiction are now considered as scientific ones.Comment: Submiited to Handbook of Exoplanets (Springer