Symptomatic porphyria

A study has been made of 7 alcoholic and 2 non-alcoholic patients with symptomatic porphyria. Siderosis (mild or absent in most cases), focal fatty change and lipofuscin pigmentation were noted on light microscopy while ultrastructural study revealed that focal cellular lysis was unexpectedly common. Unidentified cytoplasmic inclusions (possibly porphyrins) were present in 3 cases. It was concluded that increased synthesis and storage of porphyrins in the liver could lead to some cytoplasmic damage, but that alcoholic excess probably accounts for the majority of the hepatocellular abnormalities.S. Afr. Med. J., 48, 1803 (1974)

The incorporation of glycine-2-14C into urinary uric acid in normal and porphyric human subjects

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The metabolism of glycine in experimental porphyria

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Books

Medical audit Audit in Action. Ed. by Richard Smith. Pp. xiv + 245. Illustrated. £10,95. London: British Medical Journal. 1992. Available from Libriger Book Distributors, Bloemfontein.Rheumatology Bailliere's Clinical Rheumatology: Giant Cell Arteritis and Polymyalgia RheuIDatica. Guest eds B. L. Hazleman and B.-A. Bengtsson. Pp. xi + 507. illustrated. £27,50. London: Bailliere Tindall. 1991.AIDS, drugs and sexual risk AIDS, Drugs and Sexual Risk. By N. McKeganey and M. Bamard. Johannesburg: Random Century. 1992.Radiation When is a Dose Not a Dose? By Victor P. Bond. Pp. 39. Illustrated. Bethesda: National Council on Radiation Protection and Measurements. 1992.Autoimmune disease Clinical and Molecular Aspects of Autoimmune Diseases. Vol. 8. Ed. by J. M. Cruse and R. E. Lewis. Pp. x + 258. Illustrated. SFr. 248. Basel: Karger. 1992.Biochemical toxicology Principles of Biochemical Toxicology. 2nd ed. By J. A. Timbrel!. Illustrated. Pp. 415. RI53,73. London: Taylor & Frands. 1991.Advances in pineal research Advances in Pineal Research. Vol. 6. Ed. by Andrew Foldes and R. J. Reiter. pp. viii + 286. illustrated. £32,50. London: John Libbey. 1991.Health care for the future The Future of Health Care. Pp. 83. Illustrated. London: British Medical Journal. 1992.STDs and AIDS School Health Education to Prevent AIDS and Sexually Transmitted Disease. Pp. 79. SFr. 18. Geneva: World Health Organisation. 1992