315 research outputs found
...with liberty and justice for all : toward tolerant public discourse
This paper will examine the titles of several conservative and progressive religions and political organizations to demonstrate how some rhetors are distorting the lexicon of civil religion to conflate sectarian beliefs with political ambitions. While there is nothing inherently sinister about promoting sectarian beliefs, intentionally failing to differentiate between religion and politics muddies the public discourse and can be a means to justify intolerance toward opposing viewpoints
Evaluating and comparing the safety and efficacy of rimegepant versus lasmiditan in aborting acute migraine headaches in the adult migraineur
Migraine headaches are one of the most common causes of primary headaches and one of the leading causes of disability worldwide. While the mechanism of migraines are not entirely understood, they can result in significant disability (DynaMed, 2023). Dihydroergotamine was introduced for migraine treatment in the 1920s and in the 1990s triptans were introduced and have been the mainstay of acute migraine treatment since their introduction (Solomon et al., 2008). In recent years, there have been several developments in the acute treatment and prophylaxis of migraine headaches. CGRP receptor antagonists and 5-HT1F receptor agonists have been researched, developed, and approved by the FDA for acute migraine treatment. The purpose of this literature review was to compare the efficacy and safety of rimegepant, a CGRP receptor antagonist and lasmiditan, a 5HT1F receptor antagonist in the treatment of acute migraine attacks. This comparison was accomplished by a thorough review of scientific articles available through various resources such as PubMed, Clinical Key and CINAHL Complete. The results from 12 clinic trials that were reviewed indicated that rimegepant and lasmiditan are both superior to placebo in aborting an acute migraine in addition to eliminating most bothersome associated symptoms. Rimegepant and lasmiditan were also proved to be safe in the tested populations although each pharmacological intervention does carry its own set of potential side effects. There have been no direct studies comparing both drugs or comparing the drugs to triptans, however several meta-analyses showed triptans to still be superior in aborting acute migraine headacheshttps://commons.und.edu/pas-grad-posters/1268/thumbnail.jp
Evaluating and Comparing the Safety and Efficacy of Rimegepant Versus Lasmiditan in Aborting Acute Migraine Headaches in the Adult Migraineur
Migraine headaches are one of the most common causes of primary headaches. Worldwide, migraines are one of the leading causes of disability and while the mechanism of migraines are not entirely understood, they result in significant disability for those who experience them. Dihydroergotamine was introduced for migraine treatment in the 1920s and in the 1990s triptans were introduced and have been the mainstay of acute migraine treatment since their introduction. In recent years, there have been several developments in the acute treatment and prophylaxis of migraine headaches. Some of the more widely studied and recently developed interventions include calcitonin gene related peptide (CGRP) receptor antagonists and 5-HT1F receptor agonists. These have been researched, developed, and approved by the FDA for acute migraine treatment. The purpose of this literature review was to compare the efficacy and safety of rimegepant, a CGRP receptor antagonist and lasmiditan, a 5HT1F receptor antagonist in the treatment of acute migraine attacks. This comparison was accomplished by a thorough review of scientific articles available through various resources such as PubMed, Clinical Key and CINAHL Complete. The results from various clinic trials indicated that rimegepant and lasmiditan are both superior to placebo in aborting an acute migraine in addition to eliminating most bothersome associated symptoms. Rimegepant and lasmiditan were also proved to be safe in the tested populations although each pharmacological intervention does carry its own set of potential side effects. There have been no direct studies comparing both drugs or comparing the drugs to triptans, however several meta analyses showed triptans to still be superior in aborting acute migraine headaches
The Benefit of Lean Techniques Interfaced with Modular Construction
The construction industry as a whole has not been keeping up with other industries in regards to its use and implementation of new technologies and techniques that can make the process better, faster, and more cost effective. On the whole there are two strategies that can be used to benefit the construction industry in numerous ways. The first thing that can be done is to implement Lean techniques. The other strategy that can be used is called modular construction. The tangible benefits of these two items can increase the quality of the product, reduce the cost of the final product, shorten the project duration, decrease waste, and increase productivity per man hour. One trade that has started to use these techniques is the glazing industry. I will focus on them specifically to a highlight the benefits that have already been realized. This will hopefully encourage and show other trades the benefits of this approach
Leadership Perceptions of STEAM Curriculum Implementation from Educational Leaders in an Elementary Setting
The purpose of this qualitative case study was to understand the perceptions of administrators toward the process of STEAM curriculum implementation using a curriculum change lens. The study centers on the qualitative data gathered through the views and experiences of principals who work toward addressing the needs of a future workforce through the STEAM method. Research questions included: (1) What are administrators\u27 perceptions of implementing the STEAM curriculum approach to instruction within an elementary school? (2) What are characteristics of administrators who have guided STEAM curriculum implementation? Data were collected through questionnaires, interviews with individual leaders, and artifacts. The gathering such information aided in providing a clearer illustration of the thoughts of administrators implementing STEAM curriculum
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