Correlation between multiple modulation instability side lobes in dispersion oscillating fiber

We investigate numerically and experimentally the spectral correlation between multiple modulation instability (MI) side lobes in a dispersion oscillating fiber. By leveraging the dispersive Fourier transformation, we acquire instantaneous spectra and investigate the energy correlation between individual MI sidebands through scattergrams. We found that conjugate MI side lobes are strongly correlated while other combinations experience a very low degree of correlation, revealing that parametric processes related to each side lobe pair act quasi-independently.published_or_final_versio

O papel social e economica da mulher imigrante na região de Venda Nova do Imigrante (ES) - 1891 A 1927

Dissertação apresentada no Pragrma de Pós- Graduação de Históri

Bioavailability in soils

The consumption of locally-produced vegetables by humans may be an important exposure pathway for soil contaminants in many urban settings and for agricultural land use. Hence, prediction of metal and metalloid uptake by vegetables from contaminated soils is an important part of the Human Health Risk Assessment procedure. The behaviour of metals (cadmium, chromium, cobalt, copper, mercury, molybdenum, nickel, lead and zinc) and metalloids (arsenic, boron and selenium) in contaminated soils depends to a large extent on the intrinsic charge, valence and speciation of the contaminant ion, and soil properties such as pH, redox status and contents of clay and/or organic matter. However, chemistry and behaviour of the contaminant in soil alone cannot predict soil-to-plant transfer. Root uptake, root selectivity, ion interactions, rhizosphere processes, leaf uptake from the atmosphere, and plant partitioning are important processes that ultimately govern the accumulation ofmetals and metalloids in edible vegetable tissues. Mechanistic models to accurately describe all these processes have not yet been developed, let alone validated under field conditions. Hence, to estimate risks by vegetable consumption, empirical models have been used to correlate concentrations of metals and metalloids in contaminated soils, soil physico-chemical characteristics, and concentrations of elements in vegetable tissues. These models should only be used within the bounds of their calibration, and often need to be re-calibrated or validated using local soil and environmental conditions on a regional or site-specific basis.Mike J. McLaughlin, Erik Smolders, Fien Degryse, and Rene Rietr

Erythroid-Specific Expression of β-globin from Sleeping Beauty-Transduced Human Hematopoietic Progenitor Cells

Gene therapy for sickle cell disease will require efficient delivery of a tightly regulated and stably expressed gene product to provide an effective therapy. In this study we utilized the non-viral Sleeping Beauty (SB) transposon system using the SB100X hyperactive transposase to transduce human cord blood CD34+ cells with DsRed and a hybrid IHK–β-globin transgene. IHK transduced cells were successfully differentiated into multiple lineages which all showed transgene integration. The mature erythroid cells had an increased β-globin to γ-globin ratio from 0.66±0.08 to 1.05±0.12 (p = 0.05), indicating expression of β-globin from the integrated SB transgene. IHK–β-globin mRNA was found in non-erythroid cell types, similar to native β-globin mRNA that was also expressed at low levels. Additional studies in the hematopoietic K562 cell line confirmed the ability of cHS4 insulator elements to protect DsRed and IHK–β-globin transgenes from silencing in long-term culture studies. Insulated transgenes had statistically significant improvement in the maintenance of long term expression, while preserving transgene regulation. These results support the use of Sleeping Beauty vectors in carrying an insulated IHK–β-globin transgene for gene therapy of sickle cell disease

Experimental measurement of correlation in energy between multiple side lobes of modulation instability in dispersion oscillating fiber

Session - Nonlinear Pulse Propagation in Fiber II: no. NTh4AWe experimentally investigate the spectral correlation between multiple modulation instability side lobes in dispersion oscillating fiber. We found that parametric processes related to each side lobe pairs act quasi-independently. © 2014 OSAlink_to_OA_fulltextlink_to_OA_fulltex

Topographic Optical Fibers: New Perspectives in Guided Optics

Session: New Perspective of Fibers (ATh4C): paper no. ATh4C.3We investigate modulation instability in optical fibers which opto-geometrical parameters oscillate along the propagation axis. These “topographic” fibers provide an additional degree of freedom leading to multiple modulation instability side lobes. Experimental results are confirmed by analytical and numerical ones