1,678 research outputs found

    Breathers and kinks in a simulated crystal experiment

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    We develop a simple 1D model for the scattering of an incoming particle hitting the surface of mica crystal, the transmission of energy through the crystal by a localized mode, and the ejection of atom(s) at the incident or distant face. This is the first attempt to model the experiment described in Russell and Eilbeck in 2007 (EPL, v. 78, 10004). Although very basic, the model shows many interesting features, for example a complicated energy dependent transition between breather modes and a kink mode, and multiple ejections at both incoming and distant surfaces. In addition, the effect of a heavier surface layer is modelled, which can lead to internal reflections of breathers or kinks at the crystal surface.Comment: 15 pages, 12 figures, based on a talk given at the conference "Localized Excitations in Nonlinear Complex Systems (LENCOS)", Sevilla (Spain) July 14-17, 200

    Measurements of a fast nuclear spin dynamics in a single InAs quantum dot with positively charged exciton

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    By using highly time-resolved spectroscopy with an alternative {\sigma}+/{\sigma} - laser pulse modulation technique, we are able to measure the fast buildup and decay times of the dynamical nuclear spin polarization (DNSP) at 5 K for a single InAs quantum dot (QD) with positively charged exciton. It is shown that the nuclear dipole-dipole interaction can efficiently depolarize DNSP with a typical time constant of 500 {\mu}s in the absence of external magnetic field. By using an external field of 8 mT to suppress the nuclear dipolar interaction, the decay time turns to be mainly induced by interaction with unpaired electron and extends to about 5 ms. In addition, it is found that the time constant of hole-induced depolarization of nuclear spin is about 112 ms.Comment: 5 pages, 3 figure

    Data-Driven Web APIs Recommendation for Building Web Applications

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    The ever-increasing popularity of web APIs allows app developers to leverage a set of existing APIs to achieve their sophisticated objectives. The heavily fragmented distribution of web APIs makes it challenging for an app developer to find appropriate and compatible web APIs. Currently, app developers usually have to manually discover candidate web APIs, verify their compatibility and select appropriate and compatible ones. This process is cumbersome and requires detailed knowledge of web APIs which is often too demanding. It has become a major obstacle to further and broader applications of web APIs. To address this issue, we first propose a web API correlation graph built on extensive data about the compatibility between web APIs. Then, we propose WAR (Web APIs Recommendation), the first data-driven approach for web APIs recommendation that integrates API discovery, verification and selection operations based on keywords search over the web API correlation graph. WAR assists app developers without detailed knowledge of web APIs in searching for appropriate and compatible APIs by typing a few keywords that represent the tasks required to achieve app developers’ objectives. We conducted large-scale experiments on 18,478 real-world APIs and 6,146 real-world apps to demonstrate the usefulness and efficiency of WAR

    A YOLOV8-based approach for steel plate surface defect detection

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    Hot-rolled steel strips are a commonly used product in both production and daily life. However, the manufacturing process inevitably leads to the occurrence of surface defects. To solve this problem, Our method uses YOLOV8 and squeeze-and-excitation (SE) attention mechanism to detect surface defects in hot-rolled steel strips. Our method balances accuracy and real-time performance, while detecting four common surface defects. The method has an average accuracy of 90,9 % and a maximum accuracy of 98,5 % for detecting a single category of surface defects. Experimental results confirm good performance of our proposed method in classifying and localizing surface defects in hot-rolled steel strips, and has the potential for broad application and promotion

    A YOLOV8-based approach for steel plate surface defect detection

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    Hot-rolled steel strips are a commonly used product in both production and daily life. However, the manufacturing process inevitably leads to the occurrence of surface defects. To solve this problem, Our method uses YOLOV8 and squeeze-and-excitation (SE) attention mechanism to detect surface defects in hot-rolled steel strips. Our method balances accuracy and real-time performance, while detecting four common surface defects. The method has an average accuracy of 90,9 % and a maximum accuracy of 98,5 % for detecting a single category of surface defects. Experimental results confirm good performance of our proposed method in classifying and localizing surface defects in hot-rolled steel strips, and has the potential for broad application and promotion

    Magnetic phase transitions and entropy change in layered NdMn1.7Cr0.3Si2

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    A giant magnetocaloric effect has been observed around the Curie temperature, TC ∼ 42 K, in NdMn1.7Cr0.3Si2 with no discernible thermal and magnetic hysteresis losses. Below 400 K, three magnetic phase transitions take place around 380 K, 320 K and 42 K. Detailed high resolution synchrotron and neutron powder diffraction (10-400 K) confirmed the magnetic transitions and phases as follows: TN intra ∼ 380 K denotes the transition from paramagnetism to intralayer antiferromagnetism (AFl), TN inter ∼ 320 K represents the transition from the AFl structure to the canted antiferromagnetic spin structure (AFmc), while TC ∼ 42 K denotes the first order magnetic transition from AFmc to canted ferromagnetism (Fmc + F(Nd)) due to ordering of the Mn and Nd sub-lattices. The maximum values of the magnetic entropy change and the adiabatic temperature change, around TC for a field change of 5 T are evaluated to be −ΔSM max ∼ 15.9 J kg−1 K−1 and ΔTad max ∼ 5 K, respectively. The first order magnetic transition associated with the low levels of hysteresis losses (therma

    Senescent stromal cells promote cancer resistance through SIRT1 loss-potentiated overproduction of small extracellular vesicles

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    Cellular senescence is a potent tumor-suppressive program that prevents neoplastic events. Paradoxically, senescent cells develop an inflammatory secretome, termed the senescence-associated secretory phenotype (SASP), which is implicated in age-related pathologies including cancer. Here we report that senescent cells actively synthesize and release small extracellular vesicles (sEVs) with a distinctive size distribution. Mechanistically, SIRT1 loss supported accelerated sEV production despite enhanced proteome-wide ubiquitination, a process correlated with ATP6V1A downregulation and defective lysosomal acidification. Once released, senescent stromal sEVs significantly altered the expression profile of recipient cancer cells and enhanced their aggressiveness, specifically drug resistance mediated by expression of ATP binding cassette subfamily B member 4 (ABCB4). Targeting SIRT1 with agonist SRT2104 prevented development of cancer resistance by restraining sEV production by senescent stromal cells. In clinical oncology, sEVs in peripheral blood of posttreatment cancer patients were readily detectable by routine biotechniques, presenting an exploitable biomarker to monitor therapeutic efficacy and predict long-term outcome. Together, this study identifies a distinct mechanism supporting pathological activities of senescent cells and provides a potent avenue to circumvent advanced human malignancies by co-targeting cancer cells and their surrounding microenvironment, which contributes to drug resistance via secretion of sEVs from senescent stromal cells
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