<i>In vitro</i> and <i>in vivo</i> developmental rates of prepubertal and adult oocytes cultured pre- and during IVM with or without cAMP modulators.

<p><i>In vitro</i> and <i>in vivo</i> developmental rates of prepubertal and adult oocytes cultured pre- and during IVM with or without cAMP modulators.</p

Total number of OPU sessions, total number of follicles, total number of oocytes per donor and suitable for IVM obtained via ovum pick up in adult and prepubertal donors.

<p>Total number of OPU sessions, total number of follicles, total number of oocytes per donor and suitable for IVM obtained via ovum pick up in adult and prepubertal donors.</p

Gene expression profiles in expanded blastocysts produced from adult and prepubertal oocytes treated with or without cAMP modulators prior to and during IVM.

<p>Data are shown as the mean ± SEM (n = 12). Data were analyzed using two-way ANOVA followed by a Tukey's range test. The asterisk represents statistical significance among treatments for the same transcript; <i>P</i> < 0.05. <i>In vivo</i> produced expanded blastocysts were used for comparison. The mRNA relative abundance of the EGR1 gene was lower in all <i>in vitro</i> derived blastocysts compared to <i>in vivo</i> produced counterparts. No differences among treatments were found for <i>DNMT3b</i>, <i>BCL2L1</i>, <i>PRDX1</i>, <i>SLC2A8</i>.</p