613 research outputs found

    Defeating the Kalka--Teicher--Tsaban linear algebra attack on the Algebraic Eraser

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    The Algebraic Eraser (AE) is a public key protocol for sharing information over an insecure channel using commutative and noncommutative groups; a concrete realization is given by Colored Burau Key Agreement Protocol (CBKAP). In this paper, we describe how to choose data in CBKAP to thwart an attack by Kalka--Teicher--Tsaban

    Defeating the Ben-Zvi, Blackburn, and Tsaban Attack on the Algebraic Eraser

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    The Algebraic Eraser Diffie-Hellman (AEDH) protocol was introduced in 2005 and published in 2006 by Anshel-Anshel-Goldfeld-Lemieux as a protocol suitable for use on platforms with constrained computational resources, such as FPGAs, ASICs, and wireless sensors. It is a group-theoretic cryptographic protocol that allows two users to construct a shared secret via a Diffie-Hellman-type scheme over an insecure channel. Building on the refuted 2012 permutation-based attack of Kalka-Teichner-Tsaban, in 2015 Ben-Zvi-Blackburn-Tsaban (BBT) presented a heuristic attack that attempts to recover the AEDH shared secret. In their paper BBT reference the AEDH protocol as presented to ISO for certification (ISO 29167-20) by SecureRF. The ISO draft contains two profiles using the Algebraic Eraser. One profile is unaffected by this attack; the second profile is subject to their attack provided the attack runs in real time. This is not the case in most practical deployments. The BBT attack is simply a targeted attack that does not attempt to break the method, system parameters, or recover any private keys. Rather, its limited focus is to recover the shared secret in a single transaction. In addition, the BBT attack is based on several conjectures that are assumed to hold when parameters are chosen according to standard distributions, which can be mitigated, if not avoided. This paper shows how to choose special distributions so that these conjectures do not hold making the BBT attack ineffective for braid groups with sufficiently many strands. Further, the BBT attack assumes that certain data is available to an attacker, but there are realistic deployment scenarios where this is not the case, making the attack fail completely. In summary, the BBT attack is flawed (with respect to the SecureRF ISO draft) and, at a minimum, over-reaches as to its applicability

    Amiodarone for the treatment and prevention of ventricular fibrillation and ventricular tachycardia

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    Amiodarone has emerged as the leading antiarrhythmic therapy for termination and prevention of ventricular arrhythmia in different clinical settings because of its proven efficacy and safety. In patients with shock refractory out-of-hospital cardiac arrest and hemodynamically destabilizing ventricular arrhythmia, amiodarone is the most effective drug available to assist in resuscitation. Although the superiority of the transvenous implantable cardioverter defibrillator (ICD) over amiodarone has been well established in the preventive treatment of patients at high risk of life-threatening ventricular arrhythmias, amiodarone (if used with a beta-blocker) is the most effective antiarrhythmic drug to prevent ICD shocks and treat electrical storm. Both the pharmacokinetics and the electrophysiologic profile of amiodarone are complex, and its optimal and safe use requires careful patient surveillance with respect to potential adverse effects

    Renal Function in Suckling and Fasting Pups of the Northern Elephant Seal

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    Elephant seals fast for prolonged periods without access to water. This is made possible, in part, by reductions in urine production. However, the mechanisms involved in reducing urine production are not understood. In this study, glomerular filtration rate (GFR) was measured in five northern elephant seal pups (Mirounga angustirostris) via the inulin clearance technique. Measurements were made during day 9 and day 18–22 of nursing and the second and eighth week of the postweaning fast. Plasma aldosterone and cortisol concentrations, quantified by radioimmunoassay, were measured in eight other weanlings during the second and eighth week of the fast. Mean GFR was 79.3±29.3 ml/min during the early suckling period and 78.2±17.1, 89.8±52.7, and 80.4±12.2 ml/min during the late suckling, early fasting and late fasting periods, respectively. Differences between nursing and fasting were insignificant, possibly because reduced protein oxidation during suckling and rapid recruitment of protein for tissue synthesis obviated the need for postprandial hyperfiltration. Alternatively, maintenance of GFR during fasting may facilitate urea concentration by compensating for reductions in the fractional excretion of urea. It is further hypothesized that aldosterone is primarily responsible for mediating renal water reabsorption in this system

    Angiotensin II and Aldosterone Increase with Fasting in Breeding Adult Male Northern Elephant Seals (Mirounga angustirostris)

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    The renin‐angiotensin‐aldosterone system (RAAS) appears to contribute significantly to osmoregulation of fasting northern elephant seal (Mirounga angustirostris) pups; however, RAAS has not been characterized in fasting adult seals. Therefore, this study examined the contribution of RAAS to water turnover rates in fasting adult male northern elephant seals. Blood samples were obtained twice during their breeding fast at an interval of 6.5 wk, and water efflux rate was estimated by isotopic dilution during the same period. Serum electrolytes (Na+, K+, Cl−) and osmolality were unaltered between the two sampling periods, indicating ionic and osmotic homeostasis during the fast. Despite the lack of an increase in vasopressin, serum angiotensin II and aldosterone were increased and were significantly and positively correlated. Changes in aldosterone concentration and water efflux rate were significantly and negatively correlated, suggesting that the greater the increase in aldosterone, the smaller the loss of water. Adult male seals maintain ionic and osmotic homeostasis similar to that of fasting weaned pups, and this homeostasis appears to be mediated, at least in part, by RAAS, which probably contributes to increased water retention as well. The hormonal mechanisms by which northern elephant seals maintain water and electrolyte balance during fasting conditions appear to be similar regardless of age

    The Institute of Archaeology & Siegfried H. Horn Museum Newsletter Volume 39.2

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    ASOR 2017 Annual Meeting, Paul J. Ray, Jr. Hess Lecture, Dorian Alexander Random Surveyhttps://digitalcommons.andrews.edu/iaham-news/1074/thumbnail.jp

    Randomized controlled comparison of antitachycardia pacing algorithms for termination of ventricular tachycardia

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    AbstractObjectives. This study compared the efficacy and safety of two antitachycardia pacing algorithms in the treatment of ventricular tachycardia.Background. There is agreement that antitachycardia pacing should be adapted to tachycardia rate and be delivered in a burst, but the ideal pacing pattern is not well understood. Effective antitachycardia pacing burst patterns include those with a between-burst decrement (SCAN) with or without an additional within-burst decrement (RAMP).Methods. Prospective randomized crossover comparison of two antitachycardia pacing algorithms (RAMP vs. SCAN) on identical induced sustained ventricular tachycardias was performed.Results. Sixty-five ventricular tachycardias (mean cycle length 364 ± 74 ms) from 37 invasive studies performed in 29 patients were studied; 86% of patients had coronary artery disease and 72% were receiving antiarrhythmic therapy at the time of study. Of the 65 tachycardias, 40 were identical pairs and 25 were unpaired (including 8 with a >30-ms difference in cycle length of induced ventricular tachycardia pairs). In the paired pacing trials, conversion to sinus rhythm occurred, respectively, in 85% of SCAN versus 90% of RAMP protocols (p = 0.63, power = 93%) and within 1.4 ± 0.7 versus 1.7 ± 1.1 attempts (p = 0.41). Discordance for pacing success was seen in taree paris. In unpaired trials, conversion to sinus rhythm occurred in 73% and 57%, respectively (p = 0.68, power = 88%). Tachycardia acceleration during pacing occurred in 7 (11%) of 65 attempts (5 SCAN, 2 RAMP). Acceleration in unpaired ventricular tachycardia trials was correlated with tachycardia cycle length. Failure to convert ventricular tachycardia was associated with a shorter tachycardia cycle length (p < 0.05).Conclusions. In the patients studied, adaptive antiachysardia pacing was safe and effective and, when successful, occurred within three attempts of an 8-beat adaptive barst algorithm. Changes in burst pattern did not affect pacing safety or efficacy. Antitachycardia pacing success was dependent on induced ventricular tachycardia cycle length

    The Institute of Archaeology & Siegfried H. Horn Museum Newsletter Volume 39.4

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    Stordalen Lecture, Dorian Alexander Regional ASOR, Paul J. Ray, Jr. Random Surveyhttps://digitalcommons.andrews.edu/iaham-news/1076/thumbnail.jp
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