4 research outputs found
Demographics of subjects with successfully obtained HIV-1 <i>pol</i> sequences.
<p>Demographics of subjects with successfully obtained HIV-1 <i>pol</i> sequences.</p
Success probability of future regimen by the EuResist prediction engine.
<p>Prediction is based on drug resistance mutation profile and data on previous drug exposure, age, gender and CD4 at failure. Results are presented in ordered of increasing difference between a scenario where all approved NRTIs, NNRTIs and PIs are available versus currently available drugs in Tanzania. A) subjects failing first line therapy; B) subjects failing second line therapy (viral load included in prediction model).</p
Genotypic sensitivity scores for all reverse transcriptase and protease inhibitors.
<p>Percentage (%) of patient strains classified as susceptible, intermediate or resistant as per the Rega V.9.1.0 algorithm; first line failure (n = 43) and second line virological failure cases (n = 26) presented with separate paired bars (first line left bar, second line right bar).</p
Antiretroviral drug resistance mutations in Tanzanian subjects at first line clinico-immunological ART failure.
<p>A) stratified by treatment duration (n = 38); B) stratified by CD4 cells at failure (n = 36).</p