Genes encoding multiple forms of phospholipase A(2) are expressed in immature forms of human leukemic blasts.

International audiencenon

Practical Access to Aromatic Thiocyanates by CuCN-Mediated Direct Aerobic Oxidative Cyanation of Thiophenols and Diaryl Disulfides

International audienceThe practical and mild aerobic oxidative CuCN-mediated cyanation of thiophenols and diaryl disulfides was investigated. The reaction was performed in air at room temperature and reached aromatic thiocyanates in moderate to good yields starting from a broad range of diversely functionalized substrates

ESTUDOS CÉLTICOS EM RESENHA: ANTIGAS IDENTIDADES, NOVOS PARADIGMAS

Os Estudos Célticos são, por sua natureza própria, multidisciplinares e transnacionais. Proporcionam, portanto, um grande leque de abordagens, desde a antiguidade até a modernidade, sabendo-se que a marca distintiva em relação às outras disciplinas das humanidades é o fato de que os Estudos Célticos estão intrinsecamente ligados à Arqueologia e à Linguística histórica...

Intramolecular inverse electron-demand [4+2] cycloadditions of ynamidyl-tethered pyrimidines: Comparative studies in trifluorotoluene and sulfolane

International audienceThree representative 6,7-dihydro-5H-cyclopenta[b]pyridin-4-amines were synthesized using an intramolecular inverse electron demand heteroeDielseAlder/retroeDielseAlder sequence between pyrimidines (acting as azadienes) and ynamides (acting as dienophiles). Two solvents of this reaction, sulfolane and trifluorotoluene, were compared at 210 C and the former consistently led to higher yields. In addition, these studies confirmed the importance of the steric bulk of the C5-position of the pyrimidinyl cycloaddition precursor