Supplementary Material for: Treatment and Outcomes of Working Aged Adults with Stroke: Results from a National Prospective Registry

<b><i>Background:</i></b> Given the potential differences in etiology and impact, the treatment and outcome of younger patients (aged 18–64 years) require examination separately to older adults (aged ≥65 years) who experience acute stroke. <b><i>Methods:</i></b><i></i> Data from the Australian Stroke Clinical Registry (2010–2015) including demographic and clinical characteristics, provision of evidence-based therapies and health-related quality of life (HRQoL) post-stroke was used. Descriptive statistics and multilevel regression models were used for group comparisons. <b><i>Results:</i></b> Compared to older patients (age ≥65 years) among 26,220 registrants, 6,526 (25%) younger patients (age 18–64 years) were more often male (63 vs. 51%; <i>p</i> < 0.001), born in Australia (70 vs. 63%; <i>p</i> < 0.001), more often discharged home from acute care (56 vs. 38%; <i>p</i> < 0.001), and less likely to receive antihypertensive medication (61 vs. 73%; <i>p</i> < 0.001). Younger patients had a 74% greater odds of having lower HRQoL compared to an equivalent aged-matched general population (adjusted OR 1.74, 95% CI 1.56–1.93, <i>p</i> < 0.001). <b><i>Conclusions:</i></b><i></i> Younger stroke patients exhibited distinct differences from their older counterparts with respect to demographic and clinical characteristics, prescription of antihypertensive medications and residual health status