Reverse Signaling of Tumor Necrosis Factor Superfamily Proteins in Macrophages and Microglia: Superfamily Portrait in the Neuroimmune Interface

The tumor necrosis factor (TNF) superfamily (TNFSF) is a protein superfamily of type II transmembrane proteins commonly containing the TNF homology domain. The superfamily contains more than 20 protein members, which can be released from the cell membrane by proteolytic cleavage. Members of the TNFSF function as cytokines and regulate diverse biological processes, including immune responses, proliferation, differentiation, apoptosis, and embryogenesis, by binding to TNFSF receptors. Many TNFSF proteins are also known to be responsible for the regulation of innate immunity and inflammation. Both receptor-mediated forward signaling and ligand-mediated reverse signaling play important roles in these processes. In this review, we discuss the functional expression and roles of various reverse signaling molecules and pathways of TNFSF members in macrophages and microglia in the central nervous system (CNS). A thorough understanding of the roles of TNFSF ligands and receptors in the activation of macrophages and microglia may improve the treatment of inflammatory diseases in the brain and periphery. In particular, TNFSF reverse signaling in microglia can be exploited to gain further insights into the functions of the neuroimmune interface in physiological and pathological processes in the CNS

Optimization of Laser Fired Contact Process for the Formation of an Al-BSF Layer

The back-surface field (BSF) layer obtained through the laser fired contact (LFC) process is the key to increasing the efficiency of solar cells. In this paper, we studied the optimization of LFC process parameters—focusing on laser frequency, influence, and speed—to achieve good ohmic contacts, and to reduce the heat-affected zone (HAZ). As frequency increases, interactions between the laser and particles increase, with the particles becoming overly heated. This generates the thermal effect, in which heat is transferred to particles not directly affected by the laser—resulting in the HAZ becoming wider and deeper. Under different laser power conditions, depths of approximately 18 and 8.3 μm were observed at laser speeds of 10 and 100 mm/s, respectively. This analysis of performance variables allowed us to identify those best suited to forming an Al-BSF layer approximately 1.2 μm thick, which resulted in the best LFC procedure while minimizing the HAZ area. HAZ size was minimized at a frequency of 400 kHz, using 5 W laser power, and a laser speed of 100 mm/s, while the best cell characteristics were obtained using a laser pitch of 500 μm and a single laser process

A Novel Method to Achieve Selective Emitter Using Surface Morphology for PERC Silicon Solar Cells

Recently, selective emitter (SE) technology has attracted renewed attention in the Si solar cell industry to achieve an improved conversion efficiency of passivated-emitter rear-contact (PERC) cells. In this study, we presented a novel technique for the SE formation by controlling the surface morphology of Si wafers. SEs were formed simultaneously, that is, in a single step for the doping process on different surface morphologies, nano/micro-surfaces, which were formed during the texturing processes; in the same doping process, the nano- and micro-structured areas showed different sheet resistances. In addition, the difference in sheet resistance between the heavily doped and shallow emitters could be controlled from almost 0 to 60 Ω/sq by changing the doping process conditions, pre-deposition and driving time, and temperature. Regarding cell fabrication, wafers simultaneously doped in the same tube were used. The sheet resistance of the homogeneously doped-on standard micro-pyramid surface was approximately 82 Ω/sq, and those of the selectively formed nano/micro-surfaces doped on were on 62 and 82 Ω/sq, respectively. As a result, regarding doped-on selectively formed nano/micro-surfaces, SE cells showed a JSC increase (0.44 mA/cm2) and a fill factor (FF) increase (0.6%) with respect to the homogeneously doped cells on the micro-pyramid surface, resulting in about 0.27% enhanced conversion efficiency

Cell-to-Module Simulation Analysis for Optimizing the Efficiency and Power of the Photovoltaic Module

A 60-cell photovoltaic (PV) module was analyzed by optimizing the interconnection parameters of the solar cells to enhance the efficiency and increase the power of the PV module setup. The cell-to-module (CTM) losses and gains varied substantially during the various simulation iterations. Optimization was performed to inspect and augment the gain and loss parameters for the 60-cell PV module. The power and efficiency of the module were improved by refining several parameters, such as number of busbars, size of the contact pads, interconnected ribbon width, thickness of the core, and distance between the solar cells and strings, to obtain the maximum efficiency of 21.09%; the CTM efficiency achieved was 94.19% for the proposed strategy related to the common interconnection setup of the ribbon-based system. The CTM efficiency was improved by optimizing the geometrical, optical, and electrical parameters precisely, the power enhancement was up to 325.3 W, and a CTM power of 99.1% was achieved from a standard PV module with rectangular ribbon interconnections

Cell-to-Module Simulation Analysis for Optimizing the Efficiency and Power of the Photovoltaic Module

A 60-cell photovoltaic (PV) module was analyzed by optimizing the interconnection parameters of the solar cells to enhance the efficiency and increase the power of the PV module setup. The cell-to-module (CTM) losses and gains varied substantially during the various simulation iterations. Optimization was performed to inspect and augment the gain and loss parameters for the 60-cell PV module. The power and efficiency of the module were improved by refining several parameters, such as number of busbars, size of the contact pads, interconnected ribbon width, thickness of the core, and distance between the solar cells and strings, to obtain the maximum efficiency of 21.09%; the CTM efficiency achieved was 94.19% for the proposed strategy related to the common interconnection setup of the ribbon-based system. The CTM efficiency was improved by optimizing the geometrical, optical, and electrical parameters precisely, the power enhancement was up to 325.3 W, and a CTM power of 99.1% was achieved from a standard PV module with rectangular ribbon interconnections

Controlling Residual Lithium in High-Nickel (>90%) Lithium Layered Oxides for Cathodes in Lithium-Ion Batteries

The rampant generation of lithium hydroxide and carbonate impurities, commonly known as residual lithium, is a practical obstacle to the mass-scale synthesis and handling of high-nickel (>90 %) layered oxides and their use as high-energy-density cathodes for lithium-ion batteries. Herein, we suggest a simple in situ method to control the residual lithium chemistry of a high-nickel lithium layered oxide, Li(Ni0.91Co0.06Mn0.03)O-2(NCM9163), with minimal side effects. Based on thermodynamic considerations of the preferred reactions, we systematically designed a synthesis process that preemptively converts residual Li2O (the origin of LiOH and Li2CO3) into a more stable compound by injecting reactive SO(2)gas. The preformed lithium sulfate thin film significantly suppresses the generation of LiOH and Li(2)CO(3)during both synthesis and storage, thereby mitigating slurry gelation and gas evolution and improving the cycle stability.

Structurally robust lithium-rich layered oxides for high-energy and long-lasting cathodes

Abstract O2-type lithium-rich layered oxides, known for mitigating irreversible transition metal migration and voltage decay, provide suitable framework for exploring the inherent properties of oxygen redox. Here, we present a series of O2-type lithium-rich layered oxides exhibiting minimal structural disordering and stable voltage retention even with high anionic redox participation based on the nominal composition. Notably, we observe a distinct asymmetric lattice breathing phenomenon within the layered framework driven by excessive oxygen redox, which includes substantial particle-level mechanical stress and the microcracks formation during cycling. This chemo-mechanical degradation can be effectively mitigated by balancing the anionic and cationic redox capabilities, securing both high discharge voltage (~ 3.43 V vs. Li/Li+) and capacity (~ 200 mAh g−1) over extended cycles. The observed correlation between the oxygen redox capability and the structural evolution of the layered framework suggests the distinct intrinsic capacity fading mechanism that differs from the previously proposed voltage fading mode

Controlling Residual Lithium in High‐Nickel (>90 %) Lithium Layered Oxides for Cathodes in Lithium‐Ion Batteries

The rampant generation of lithium hydroxide and carbonate impurities, commonly known as residual lithium, is a practical obstacle to the mass-scale synthesis and handling of high-nickel (>90 %) layered oxides and their use as high-energy-density cathodes for lithium-ion batteries. Herein, we suggest a simple in situ method to control the residual lithium chemistry of a high-nickel lithium layered oxide, Li(Ni0.91Co0.06Mn0.03)O-2(NCM9163), with minimal side effects. Based on thermodynamic considerations of the preferred reactions, we systematically designed a synthesis process that preemptively converts residual Li2O (the origin of LiOH and Li2CO3) into a more stable compound by injecting reactive SO(2)gas. The preformed lithium sulfate thin film significantly suppresses the generation of LiOH and Li(2)CO(3)during both synthesis and storage, thereby mitigating slurry gelation and gas evolution and improving the cycle stability.

High-Energy and Long-Lasting Organic Electrode for a Rechargeable Aqueous Battery

© 2022 American Chemical Society.Redox-active organic materials (ROMs) hold great promise as potential electrode materials for eco-friendly, cost-effective, and sustainable batteries; however, the poor cycle stability arising from the chronic dissolution issue of the ROMs in generic battery systems has impeded their practical employment. Herein, we present that a rational selection of electrolytes considering the solubility tendency can unlock the hidden full redox capability of the DMPZ electrode (i.e., 5,10-dihydro-5,10-dimethylphenazine) with unprecedentedly high reversibility. It is demonstrated that a multiredox activity of DMPZ/DMPZ+/DMPZ2+, which has been previously regarded to degrade with repeated cycles, in the newly designed electrolyte can be utilized with surprisingly robust cycle stability over 1000 cycles at 1C. This work signifies that tailoring the electrode-electrolyte compatibility can possibly unleash the hidden potential of many common ROMs, catalyzing the rediscovery of organic electrodes with long-lasting and high energy density.11Nsciescopu