1 research outputs found
Lewis Acid-Catalyzed Annulations of Geminally Disubstituted Cyclopropanes with Aldehydes or 1,3,5-Triazinanes
Under the catalysis of simple Lewis acid catalysts, 2-(1-aroylcyclopropyl)malonates
demonstrated unique reactivities in annulation reactions with aryl/alkyl
aldehydes, paraformaldehyde, and 1,3,5-triazinanes. Three types of
structurally diverse cyclic products that are otherwise not easy to
obtain were generated in moderate to good yields and excellent diastereoselectivities.
Possible reaction pathways leading to these products were proposed
on the basis of the results of control experiments