Ethnic and Gender Differences in Psychosocial Factors in Native Hawaiian, other Pacific Islanders, and Asian American Adults with Type 2 Diabetes

This study examined the differences between 207 Asians and Native Hawaiian, other Pacific Islanders (NHOPI) with type 2 diabetes among various psychosocial measures. Responses to five multivariable regression models including the Diabetes Quality of Life Questionnaire (DQOL) and Short Form -36® Health Survey (SF-36) were analyzed. Differences were determined by linear contrasts in the multivariate linear regression models after adjusted for multiple demographic and socioeconomic variables. Compared to Asians, NHOPIs perceived a lower impact of diabetes on their quality of life; highlighting differences in perceptions of self-efficacy and self-care activities. Females did better on their diet while males perceived better social support. Approaches to diabetes treatment decisions should include ethnic and cultural differences that may impact treatment outcomes

On the Management of Scientific Research Work in Colleges and Universities of Western Areas

According to the existing condition analysis of academic research management in colleges and universities of the western areas, pointing out there being some existing problems at present, and putting forward to the countermeasures solving these problems. Thinking, as for the colleges and universities of the western areas, on the management of academic research work, are supposed to grasp the complication of it, highlight the local unique features, strengthen the ability of serving local economic, and take an important part in the local economic development

INTERVENTION EFFECT OF THEME BUILDING BLOCK GAMES ON THE MENTAL HEALTH AND BEHAVIOR OF CHILDREN WITH ATTENTION DEFICIT HYPERACTIVITY DISORDER

Background: Children with attention deficit hyperactivity disorder (ADHD) are mainly characterized by learning difficulties, emotional impulsion, excessive activity, and distracted attention, which have a certain impact on their social ability, physical and mental health, and their living ability. This study aims to explore the effects of theme building block games on the psychological behaviors of children with ADHD, and to provide some reference for promoting the mental health development of children with ADHD. Subjects and methods: A total of 180 children with ADHD in Healthcare Center for Children from January 2020 to June 2021 were selected via convenient sampling. They were randomly divided into control (n=90) and observation (n=90) groups. Children in the control and observation groups received routine and theme building block games, respectively, once a week and a total of 8 weeks of building block game interventions. Improvement of symptoms, Eysenck Personality Questionnaire (EPQ), Achenback Child Behavior Scale List (CBLC), Child Sensory Integration Development Scale, and Piers-Harris Child Self-concept Scale (PHCSS) of two groups were compared before and after intervention. Results: After intervention, children in the two groups showed lower T scores in P and N, and higher T scores in E and L of EPQ; T scores of children in the observation group improved more significantly. Children (boys) in the two groups showed lower scores in discipline violation, hostility, compulsion, immaturity, poor communication, schizophrenia-like, and physical complaints in CBCL. Moreover, those in the observation group obtained significantly lower scores in CBCL than those in the control group. Children (girls) in the two groups showed lower scores in cruelty, aggressiveness, immaturity, depression withdrawal, schizophrenia- like, somatic complaints, and anxiety compulsion in CBCL. Meanwhile, those in the observation group obtained significantly lower scores in CBCL than those in the control group. After intervention, scores of children in the two groups in symptom improvement, sensory integration ability, and PHCSS were significantly improved. Lastly, those in the observation group obtained higher scores in these aspects compared with those in the control group. Conclusions: The theme building block game can effectively improve symptoms of children with ADHD and also help promote their sensory integration ability, self-concept, and personality development, as well as improve their psychological and behavioral status. Accordingly, this rehabilitation intervention method is worthy of promotion, which can be recognized and accepted easily

Repression of hla by rot Is Dependent on sae in Staphylococcus aureus

The regulatory locus sae is a two-component system in Staphylococcus aureus that regulates many important virulence factors, including alpha-toxin (encoded by hla) at the transcriptional level. The SarA homologs Rot and SarT were previously shown to be repressors of hla in selected S. aureus backgrounds. To delineate the interaction of rot and sae and the contribution of sarT to hla expression, an assortment of rot and sae isogenic single mutants, a rot sae double mutant, and a rot sae sarT markerless triple mutant were constructed from wild-type strain COL. Using Northern blot analysis and transcriptional reporter gene green fluorescent protein, fusion, and phenotypic assays, we found that the repression of hla by rot is dependent on sae. A rot sae sarT triple mutant was not able to rescue the hla defect of the rot sae double mutant. Among the three sae promoters, the distal sae P3 promoter is the strongest in vitro. Interestingly, the sae P3 promoter activities correlate with hla expression in rot, rot sae, and rot sae sarT mutants of COL. Transcriptional study has also shown that rot repressed sae, especially at the sae P3 promoter. Collectively, our data implicated the importance of sae in the rot-mediated repression of hla in S. aureus

2-[(E)-2-(Nitro­methyl­idene)imidazolidin-1-yl]ethanol

In the title compound, C6H11N3O3, the imidazolidine NH group is involved in a three-center N—H⋯O hydrogen bond, with intra­molecular and inter­molecular branches, to the nitro group O atoms. The centrosymmetric dimers that are formed are further connected by O—H⋯O hydrogen bonds between the hy­droxy and nitro groups into a two-dimensional polymeric structure extending parallel to (101)

1-[(6-Chloro-3-pyrid­yl)meth­yl]-5-eth­oxy-8-nitro-1,2,3,5,6,7-hexa­hydro­imidazo[1,2-a]pyridine

In the title compound, C15H19ClN4O3, an active agrochemical possessing insecticidal activity, the dihedral angle between the mean planes passing through the pyridine ring and the five-membered ring is 87.3 (2)°. The fused pyridine ring adopts a twisted sofa conformation. The mol­ecular structure features close intra­molecular C—H⋯N and C—H⋯O hydrogen bonding