78 research outputs found

    Numerical Research About the Internal Flow of Steam-jet Vacuum Pump: Evaluation of Turbulence Models and Determination of the Shock-mixing Layer

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    AbstractSteam-jet vacuum pump is widely used in a range of applications. This paper evaluated the performance of four well-known turbulence models for predicting and understanding the internal flow of a steam-jet vacuum pump first. With the help of a commercial computational fluid dynamics (CFD) code ANSYS-Fluent 6.3, the simulation results obtained from the concerned turbulence models were compared with experimental values, the k-omega-SST model was chosen as a tool model for carrying out numerical simulations. Then, based on the simulation results obtained from specific operating conditions, a method for locating the shock-mixing layer was put forward. The shape of the shock-mixing layer shows that the secondary steam does not mix with the primary steam immediately after being induced into the mixing chamber of the pump; actually, they maintain their independence till the shocking position instead. After the shock happens, the shock-mixing layer disappear, the two fluid in the pump begin to mix with each other and discharge to the next stage with almost the same state. Based on the shape of the shock-mixing layer and the supersonic region of the secondary steam, a detailed analysis for the flow duct of the secondary steam was carried out. It is found that the throat of the secondary steam flow duct plays a crucial role in maintaining a stable operating state and the length of the throat reflects the back pressure endurance for the pump

    The Basic Theory of CFD Governing Equations and the Numerical Solution Methods for Reactive Flows

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    The universal principles of fluid motion are the conservation of mass, momentum and energy. This chapter will introduce the CFD governing equations and describe how the continuity equation, component equation, Navier-Stokes equation and energy equation were derived from the principles above. With the expanding application of CFD simulation technology, some processes such as fluid-involved reactions, adsorption and permeation, which break the conservation of mass, momentum and energy for fluid phase, should be coupled to CFD model. In view of this, this chapter provided the theories about source terms for the mass equation, momentum equation and thermal energy equation. The technology for solving these governing equations remained a challenge for a long period due to the complexity. Thanks to the development of numerical methods, such as the finite difference method and the finite volume method, these equations can be solved and provide reasonable numerical results of flows, heat transfer and reactions. This chapter also demonstrates the basics of these two major numerical techniques

    Numerical modelling of micron particle inhalation in a realistic nasal airway with pediatric adenoid hypertrophy: A virtual comparison between pre- and postoperative models

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    Adenoid hypertrophy (AH) is an obstructive condition due to enlarged adenoids, causing mouth breathing, nasal blockage, snoring and/or restless sleep. While reliable diagnostic techniques, such as lateral soft tissue x-ray imaging or flexible nasopharyngoscopy, have been widely adopted in general practice, the actual impact of airway obstruction on nasal airflow and inhalation exposure to drug aerosols remains largely unknown. In this study, the effects of adenoid hypertrophy on airflow and micron particle inhalation exposure characteristics were analysed by virtually comparing pre- and postoperative models based on a realistic 3-year-old nasal airway with AH. More specifically, detailed comparison focused on anatomical shape variations, overall airflow and olfactory ventilation, associated particle deposition in overall and local regions were conducted. Our results indicate that the enlarged adenoid tissue can significantly alter the airflow fields. By virtually removing the enlarged tissue and restoring the airway, peak velocity and wall shear stress were restored, and olfactory ventilation was considerably improved (with a 16∼63% improvement in terms of local ventilation speed). Furthermore, particle deposition results revealed that nasal airway with AH exhibits higher particle filtration tendency with densely packed deposition hot spots being observed along the floor region and enlarged adenoid tissue area. While for the postoperative model, the deposition curve was shifted to the right. The local deposition efficiency results demonstrated that more particles with larger inertia can be delivered to the targeted affected area following Adenoidectomy (Adenoid Removal). Research findings are expected to provide scientific evidence for adenoidectomy planning and aerosol therapy following Adenoidectomy, which can substantially improve present clinical treatment outcomes.</p

    Numerical analysis of airflow and particle deposition in multi-fidelity designs of nasal replicas following nasal administration

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    Background and Objective: An improved understanding of flow behaviour and particle deposition in the human nasal airway is useful for optimising drug delivery and assessing the implications of pollutants and toxin inhalation. The geometry of the human nasal cavity is inherently complex and presents challenges and manufacturing constraints in creating a geometrically realistic replica. Understanding how anatomical structures of the nasal airway affect flow will shed light on the mechanics underpinning flow regulation in the nasal pharynx and provide a means to interpret flow and particle deposition data conducted in a nasal replica or model that has reduced complexity in terms of their geometries. This study aims to elucidate the effects of sinus and reduced turbinate length on nasal flow and particle deposition efficiencies. Methods: A complete nasal airway with maxillary sinus was first reconstructed using magnetic resonance imaging (MRI) scans obtained from a healthy human volunteer. The basic model was then modified to produce a model without the sinus, and another with reduced turbinate length. Computational fluid dynamics (CFD) was used to simulate flow in the nasal cavity using transient flow profiles with peak flow rates of 15 L/min, 35 L/min and 55 L/min. Particle deposition was investigated using discrete phase modelling (DPM). Results: Results from this study show that simplifying the nasal cavity by removing the maxillary sinus and curved sections of the meatus only has a minor effect on airflow. By mapping the spatial distribution of monodisperse particles (10 μm) in the three models using a grid map that consists of 30 grids, this work highlights the specific nasal airway locations where deposition efficiencies are highest, as observed within a single grid. It also shows that lower peak flow rates result in higher deposition differences in terms of location and deposition quantity, among the models. The highest difference in particle deposition among the three nasal models is ∼10%, and this is observed at the beginning of the middle meatus and the end of the pharynx, but is only limited to the 15 L/min peak flow rate case. Further work demonstrating how the outcome may be affected by a wider range of particle sizes, less specific to the pharmaceutical industries, is warranted. Conclusion: A physical replica manufactured without sections of the middle meatus could still be adequate in producing useful data on the deposition efficiencies associated with an intranasal drug formulation and its delivery device
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