On the origin of the helium-rich population in the peculiar globular cluster Omega Centauri

In this contribution we discuss the origin of the extreme helium-rich stars which inhabit the blue main sequence (bMS) of the Galactic globular cluster Omega Centauri. In a scenario where the cluster is the surviving remnant of a dwarf galaxy ingested by the Milky Way many Gyr ago, the peculiar chemical composition of the bMS stars can be naturally explained by considering the effects of strong differential galactic winds, which develop owing to multiple supernova explosions in a shallow potential well.Comment: 2 pages, 1 figure, to appear in the Proceedings of IAU Symposium No. 268, Light Elements in the Universe (C. Charbonnel, M. Tosi, F. Primas, C. Chiappini, eds., Cambridge Univ. Press

Novel challenges to psychiatry from a changing world

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Use of potassium polyaspartate for the tartaric stabilization of Sicilian white wines

Cold stabilization is a common method used to avoid tartaric acid crystals from forming in bottled wine, but this technique shows some inconveniences on the sensory characteristics and energy cost. In the present research, the tartaric stabilization in Sicilian white wines, with a recently permissible molecule in oenology, was studied: the potassium polyaspartate (PAK). The PAK has a negative charge at wine pH and allows to sequester the K+ cations; consequently it inhibits the formation and the growth of potassium bitartrate crystals. PAK is a relatively small polymer; perfectly microfiltrated and does not allow the filling phenomena in filtration membranes. The adding of PAK allowed to reduce almost all the tartaric precipitations on very unstable wines, regardless of the chemical-physical characteristics of the treated white wines. The stability of PAK, after thermal stress of the wine added to this polymer, was confirmed evaluating different analytical parameters such as pH, total acidity and buffer power, while variations in the conductivity of wines seemed to indicate a residual tartaric instability. In conclusion, the use of PAK makes possible to improve the sensory characteristics of wines, considering lower losses of tartaric acid and potassium, which are important for acid perception and acid persistence (buffer power), as well as reducing production costs and low environmental impact

Remembering Eliahu de Luna Montalto (1567-1616)

Born in Portugal and the son of Marranos (Christianized Jews from Spain), Eliahu de Luna Montalto lived during a particularly harsh period for the Jewish people. Throughout Europe, the situation for Jews was unfavorable; laws had been passed forbidding them to live in England for the past 300 years, and for the past 200 years in France. Additionally, in France, while Jews were permitted to study at some universities, the practice of medicine was forbidden to them. It is within this context that Eliahu de Luna Montalto, who had returned to his original faith (Judaism), was recruited to the French court. This paper pays tribute to Montalto’s life and medical practice—so exemplary that the Queen of France would ask Montalto to serve at the court and receive Papal permission for Montalto openly to observe his faith as a Jew, this despite the objections of the King of France

Response to the Letter to the Editor "Psychiatry's undeclared identity crisis in a changing world" by Richard Skaff

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Testicular cancer and sperm DNA damage: short- and long-term effects of antineoplastic treatment

The aim of this study was to investigate sperm DNA damage induced by chemo- and radiotherapy in patients with testicular cancer to provide data on the extent and persistence of nuclear damage that might affect individual reproductive potential. We evaluated pre- and post-antineoplastic treatment sperm DNA integrity, expressed as DNA Fragmentation Index (DFI), in a large caseload of testicular cancer patients by sperm chromatin structure assay. The mean total DFI for all patients at T0 was 18.0 ± 12.5%. Sperm chromatin profile was markedly impaired at T3 (27.7 ± 17.4%) and T6 (23.2 ± 15.3%), improving considerably at T12 and T24 (14.0 ± 8.9% and 14.4 ± 10.3%). After chemotherapy, we found a marked increase in DFI at T3 and T6 and a significant reduction at T12 and T24 in comparison with the baseline. In contrast, DFI increased at T3 and T6 after radiotherapy but the subsequent reduction was far less marked, reaching baseline values at T12 and T24. Finally, post-treatment DNA damage was not age or histotype dependent, but was more marked in the advanced stage of cancer. In this study, we showed that the chromatin profile may be affected in the months immediately following the end of the treatment, improving after 12-24 months. Our results thus indicate that post-treatment DNA damage is influenced both by the type and intensity of the therapy and by the pathological and clinical stage of the disease. © 2014 American Society of Andrology and European Academy of Andrology

Exposure to polychlorinated biphenyls and hexachlorobenzene, semen quality and testicular cancer risk

PURPOSE: We carried out a case-control study to investigate the possible role of occupational and environmental exposure to endocrine disruptors in the onset of testicular cancer (TC). METHODS: We evaluated 125 TC patients and 103 controls. Seminal fluid examination and organochlorine analysis were performed in all subjects. Cases and controls were also interviewed using a structured questionnaire to collect demographic information, residence, andrological medical history and dietary information. RESULTS: We found that a higher level of reproductive tract birth defects was associated with a higher risk of TC. With regard to diet, cases reported a higher consumption of milk and dairy products than controls. Overall, there was a statistically significant increase in TC risk in cases with detectable values of total polychlorinated organic compounds against controls (14.4 vs. 1.0 %; p < 0.001). TC patients with detectable levels of organochlorines had lower mean semen parameters than those with undetectable levels, although this difference was not statistically significant. CONCLUSION: The International Agency for Research on Cancer recently included dioxin-like polychlorinated biphenyls (PCBs) in Group 1 of known human carcinogens. Our study confirmed and identified various risk factors for testicular cancer: cryptorchidism, consumption of milk and dairy products, parents' occupation and serum concentration of hexachlorobenzene and PCBs and, for the first time, we showed the correlation between semen quality and the serum concentration of these pollutants

UAV APPLICATION IN POST - SEISMIC ENVIRONMENT

Abstract. On April 6, 2009, an earthquake of 6.3 magnitude struck central Italy with its epicentre near L'Aquila, at 42.3502° N, 13.3762° E. The earthquake damaged 3000 to 11 000 buildings in the medieval city of L'Aquila. Several buildings totally collapsed, 308 people were killed. The post emergency phase till now is just at its beginning step. Conventional surveying techniques using high precision total stations, GNSS receivers and laser scanners for investigations on damaged buildings are always becoming more automated, accurate and operative and even much more fast. Even if these techniques represent instruments of extreme operability there are still many evident limits on their use, especially regarding the survey of both the roofs and the facades of tall buildings or dangerous places, typical on post earthquake situations. So using micro UAVs for surveying in such particular cases, many of these problems can be easily bypassed. In fact, the present work aims on experimenting using multi-rotor micro UAVs, that will allow high quality image capturing on roofs and facades of structures in the old city center of L'Aquila. To obtain actual stereoscopic acquisitions of buildings some conditions on the geometry of acquisition have to be observed, for this reason, taking as a guideline classic flight photogrammetric, a flight planning software was developed. Accurate planning for UAVs acquisitions is very important also considering the reduced autonomy of such vehicles. This can be a strategic point if we want to use UAVs for early damage assessment and also for post event reconstruction planning

Rilievi laser scanner con tecniche di registrazione in situ: il sistema Topcon GLS2000 per il rilievo di siti archeologici

Il lavoro svolto presenta i risultati ottenuti durante una campagna di rilievi laser scanner in ambito archeologico effettuata utilizzando il sistema GLS2000 della Topcon. Le attività di rilievo sono state condotte per la documentazione e ricostruzione tridimensionale della Domus romana all’interno del Parco archeologico di Lilibeo a Marsala. Lo scopo del lavoro è stato quello di utilizzare e verificare le tecniche di registrazione in situ impiegando, in particolare, il metodo della poligonale