Threedimensional structure of myosin subfragment-1 from electron microscopy of sectioned crystals

Abstract. Image analysis of electron micrographs of thin-sectioned myosin subfragment-1 (Sl) crystals has been used to determine the structure of the myosin head at ti25-A resolution. Previous work established that the unit cell of type I crystals of myosin Sl contains eight molecules arranged with orthorhombic space group symmetry P2 12,2, and provided preliminary information on the size and shape of the myosin hea