Kaplan-Meier bleb survival plot of eyes in each treatment group.

<p>For each rabbit, bleb failure was declared after the bleb appeared flat in two consecutive masked clinical examinations. The first of the two dates was recorded as the endpoint.</p

Representative sections of the bleb conjunctiva taken on POD 12, H&E 250x; (A) Topical saratin; (B) Topical+2 injections of saratin; (C) Balanced saline solution; (D) Mitomycin-C.

<p>Representative sections of the bleb conjunctiva taken on POD 12, H&E 250x; (A) Topical saratin; (B) Topical+2 injections of saratin; (C) Balanced saline solution; (D) Mitomycin-C.</p

Representative sections of the implant site taken on POD 12, Masson’s Trichrome 20x; Left: Topical+2 injections of saratin; <i>asterisk</i>, mild collagen density and moderate fibroblast proliferation Middle: Balanced saline solution; Right: Mitomycin-C; <i>asterisk</i>, acellular fibrosis and necrosis.

<p>Representative sections of the implant site taken on POD 12, Masson’s Trichrome 20x; Left: Topical+2 injections of saratin; <i>asterisk</i>, mild collagen density and moderate fibroblast proliferation Middle: Balanced saline solution; Right: Mitomycin-C; <i>asterisk</i>, acellular fibrosis and necrosis.</p

Box-and-whisker plot of bleb survival for each treatment group.

<p>First and third quartiles are delineated by boxes. Whiskers represent maxima and minima.</p