16 research outputs found
Direct costs of mass vaccination campaign.
<p>Fixed administrative costs, MSF institutional costs, and costs linked to operational research are excluded.</p
Weekly number of reported cholera cases in Guinea, and Boffa and Forecariah districts, Guinea, 2012.
<p>The vaccination campaign in Boffa took place on epidemiological weeks 13 and 16 and in Forecariah on weeks 22 and 24. <i>Source: Ministry of Health, Guinea</i>.</p
First Outbreak Response Using an Oral Cholera Vaccine in Africa: Vaccine Coverage, Acceptability and Surveillance of Adverse Events, Guinea, 2012
<div><p>Background</p><p>Despite World Health Organization (WHO) prequalification of two safe and effective oral cholera vaccines (OCV), concerns about the acceptability, potential diversion of resources, cost and feasibility of implementing timely campaigns has discouraged their use. In 2012, the Ministry of Health of Guinea, with the support of Médecins Sans Frontières organized the first mass vaccination campaign using a two-dose OCV (Shanchol) as an additional control measure to respond to the on-going nationwide epidemic. Overall, 316,250 vaccines were delivered. Here, we present the results of vaccination coverage, acceptability and surveillance of adverse events.</p><p>Methodology/Principal Findings</p><p>We performed a cross-sectional cluster survey and implemented adverse event surveillance. The study population included individuals older than 12 months, eligible for vaccination, and residing in the areas targeted for vaccination (Forécariah and Boffa, Guinea). Data sources were household interviews with verification by vaccination card and notifications of adverse events from surveillance at vaccination posts and health centres. In total 5,248 people were included in the survey, 3,993 in Boffa and 1,255 in Forécariah. Overall, 89.4% [95%CI:86.4–91.8%] and 87.7% [95%CI:84.2–90.6%] were vaccinated during the first round and 79.8% [95%CI:75.6–83.4%] and 82.9% [95%CI:76.6–87.7%] during the second round in Boffa and Forécariah respectively. The two dose vaccine coverage (including card and oral reporting) was 75.8% [95%CI: 71.2–75.9%] in Boffa and 75.9% [95%CI: 69.8–80.9%] in Forécariah respectively. Vaccination coverage was higher in children. The main reason for non-vaccination was absence. No severe adverse events were notified.</p><p>Conclusions/Significance</p><p>The well-accepted mass vaccination campaign reached high coverage in a remote area with a mobile population. Although OCV should not be foreseen as the long-term solution for global cholera control, they should be integrated as an additional tool into the response.</p></div
Reason for non-vaccination among individuals not vaccinated, Boffa and Forécariah prefectures, April–June 2012.
<p>Reason for non-vaccination among individuals not vaccinated, Boffa and Forécariah prefectures, April–June 2012.</p
Target areas by the non-selective mass vaccination campaigns, Guinea, 2012.
<p>Target areas by the non-selective mass vaccination campaigns, Guinea, 2012.</p
Vaccine coverage by age group of the cholera mass vaccination campaign in Boffa (panel A) and Forécariah (panel B) prefectures, first round, second round and two doses (fully vaccinated), April–June 2012.
<p>Vaccine coverage by age group of the cholera mass vaccination campaign in Boffa (panel A) and Forécariah (panel B) prefectures, first round, second round and two doses (fully vaccinated), April–June 2012.</p
Study flow chart: Number of households visited, number of households included, number of individuals in the targeted age group (older than 12 months of age) residing in the households included in the survey and final number of individuals included in the study.
<p>Study flow chart: Number of households visited, number of households included, number of individuals in the targeted age group (older than 12 months of age) residing in the households included in the survey and final number of individuals included in the study.</p
Timeline of the cholera vaccination campaigns and implementation of the field surveys in Guinea in 2012.
<p>Months are abbreviated as follows: F = February, A = April, M = May, J = June.</p