MOX and IVM pharmacokinetic parameters of scabies-infected pig plasma and skin.

<p>MOX and IVM pharmacokinetic parameters of scabies-infected pig plasma and skin.</p

Skin MOX and IVM concentrations (mean ± SD, ng/g) after oral intake in scabies-infected pigs.

<p>Concentrations measured on D2, 7, 9, 14, 22, 36, and 47 post-treatment are depicted. Predicted parts of the curves are indicated as a dashed line. W, week; D, day.</p

Pruritus scores (mean ±SD) over time from scabies-infection induction throughout the post-treatment period for MOX- and IVM-treated groups and control pigs.

<p>W, week; D, day.</p

ELISA-assessed serological responses (expressed as mean %OD ± SD) after <i>S</i>. <i>scabiei</i> infection throughout the post-treatment period of the MOX- and IVM-treated groups and control pigs.

<p>W, week; D, day.</p

Diagram of the study design showing the 3 experimental phases: housing and acclimation phase, experimental phases 1 and 2.

<p>DXM, dexamethasone; D, day.</p

Primary outcome of MOX, IVM or no treatment of experimental scabies in pigs.

<p>Primary outcome of MOX, IVM or no treatment of experimental scabies in pigs.</p