Adjusted HR for mortality in type 2 diabetic compared with non-diabetic subjects.

<p>HR: Hazard Ratio; CI: Confidence Interval; (1) Reference: Non-diabetic subjects; (2) Reference: Toulouse; (3) Reference: 35–44 years.</p>£<p>HR for type 2 diabetics with metformin alone or with sulfonylureas (alone or in combination) = 1.85 [1.07–3.20] (p = 0.027);</p><p>* As compared with <6 years duration of diabetes (among diabetics). Duration of diabetes is composed of 3 categories (<6 years, ≥6 years and non-diabetic subjects);</p><p>** Diabetes with renal, ophthalmic, neurological, peripheral arterial disease or atherosclerotic cardiovascular disease.</p

Main baseline characteristics of participants.

<p>Of type 2 diabetic subjects, 12 were receiving other hypoglycaemic treatments. SD: Standard Deviation; IQR: Inter-Quartile Range;</p>£<p>Diabetes was assessed for subjects with fasting blood glucose ≥7.7 mmol/l (140 mg/dl) or under hypoglycaemic drug treatment;</p>££<p>Diabetic subjects treated with metformin alone;</p>£££<p>Diabetics with sulfonylureas or insulin alone or in combination;</p><p>* Diabetes with renal, ophthalmic, neurological, peripheral arterial disease or atherosclerotic cardiovascular disease;</p><p>** Among diabetics.</p

Ambient air pollution daily mean value correlation coefficients, Strasbourg (France) Metropolitan Area, 2000–2007.

<p>Ambient air pollution daily mean value correlation coefficients, Strasbourg (France) Metropolitan Area, 2000–2007.</p

Exposure to air pollution and the onset of a myocardial infarction (MI) in the Strasbourg (France) Metropolitan Area, 2000–2007, base model^a.

a<p>Associations observed for different lag times; excess odds ratios (eOR) are expressed as per cent (95% confidence interval) increase for <i>i</i>) a 1 µg/m³ increase in benzene concentrations; <i>ii</i>) a 10 µg/m³ in NO₂, O₃ and PM₁₀ concentrations and <i>iii</i>) a 100 µg/m3 increase in CO concentrations. Adjusted for the previous day maximum atmospheric pressure, same day minimum temperature and influenza epidemics.</p

Exposure to air pollution and the onset of a myocardial infarction in the Strasbourg (France) Metropolitan Area, 2000–2007, by subgroups^a.

a<p>Associations observed for different lag times; excess odds ratios (eOR) are expressed as per cent (95% confidence interval) increase for <i>i</i>) a 1 µg/m³ increase in benzene concentrations; <i>ii</i>) a 10 µg/m³ in NO₂, O₃ and PM₁₀ concentrations and <i>iii</i>) a 100 µg/m³ increase in CO concentrations. Adjusted for the previous day maximum atmospheric pressure, same day minimum temperature and influenza epidemics.</p><p>*p<0.05.</p><p>**p<0.001.</p

Myocardial infarction events (ICD-9: 410) collected by the Bas-Rhin Coronary Heart Disease Register, Strasbourg Metropolitan Area, France, 2000–2007.

<p>Myocardial infarction events (ICD-9: 410) collected by the Bas-Rhin Coronary Heart Disease Register, Strasbourg Metropolitan Area, France, 2000–2007.</p

Air pollutants daily concentrations (µg/m³) and meteorological parameters in the Strasbourg (France) Metropolitan Area, 2000–2007.

<p>Air pollutants daily concentrations (µg/m³) and meteorological parameters in the Strasbourg (France) Metropolitan Area, 2000–2007.</p

Frequency of MetS according to gender and age group.

<p>MetS indicates the metabolic syndrome; IDF, the International Diabetes Federation (MetS IDF) criteria and the National Cholesterol Education Program–Adult Treatment Panel III (MetS ATP) criteria. Numbers above each bar indicate total number of persons with MetS/total number of persons in the given age group; All <i>P</i><0.0001 for each of the 4 MetS/gender combination across age groups. Within each age group, <i>P</i><0.0001 between genders, except for MetS ATP in ages 40–49 years (<i>P</i> = 0.57).</p

Frequency of each MetS component according to gender and age group.

<p>MetS indicates the metabolic syndrome; IDF, the International Diabetes Federation; and ATPIII, Adult Treatment Panel III. The men/women ratio is 38639/30455 for all components except for waist circumference (men/women  = 23817/152899) since not all cohorts registered waist circumference. <i>P</i><0.0001 for each MetS component across age groups in men and women separately. Gender differences within each age group, with <i>P</i><0.0001^a, <i>P</i><0.01^b, <i>P</i><0.05^c, NS indicates non-significance, <i>P</i>>0.05, and the dashed line indicates the same level of significance across the age groups.</p

Age- and gender-specific incidence rates per 1000 person years for CVD with or without the presence of MetS.

<p>MetS IDF indicates the metabolic syndrome defined according to the International Diabetes Federation criteria; MetS ATP, the metabolic syndrome defined according to the National Cholesterol Eduation Program-Adult Treatment Panel III; and CVD, cardiovascular disease: (A) fatal and nonfatal CHD, (B) fatal and nonfatal stroke, and (C) cardiovascular death. Numbers above each bar indicate events/persons. Comparison of incidence rates between men and women with MetS within each age group using Pearson Chi²-test, <i>P</i><0.05^a, <i>P</i><0.0001^b, and NS indicates non-significance, <i>P</i>>0.05.</p