Demographic and clinical characteristics of patients with venous thromboembolism (VTE) and control subjects.

<p>Demographic and clinical characteristics of patients with venous thromboembolism (VTE) and control subjects.</p

<i>LPA</i> KIV-2 repeats in VTE patients.

<p><i>LPA</i> KIV-2 repeats in VTE patients.</p

Genotype distribution and minor allele frequency of the 4 <i>LPA</i> single nucleotide polymorphisms (SNPs) investigated.

<p>Genotype distribution and minor allele frequency of the 4 <i>LPA</i> single nucleotide polymorphisms (SNPs) investigated.</p

Association between KIV-2 repeat quartiles (Q1: ≤7 repeats; Q2: 8–12 repeats; Q3: 13–22 repeats; Q4: ≥23 repeats) and venous thromboembolism.

<p>Multivariate logistic regression analysis: adjusted for age, sex, hypertension, smoking habit, dyslipidemia, diabetes, BMI, hyperhomocysteinemia and oral contraceptives/HRT; Q4: reference group.</p

Receiver operating characteristic curve for association with venous thromboembolism in the whole population.

<p>Variables included in the models: Genetic = KIV-2 repeats; Clinical = age, sex, hypertension, smoking habit, dyslipidemia, diabetes, BMI, hyperhomocysteinemia, and oral contraceptives/HRT; Combined = Genetic + Clinical variables.</p

Characteristics of the 4 selected <i>LPA</i> gene single nucleotide polymorphisms (SNPs).

<p>Characteristics of the 4 selected <i>LPA</i> gene single nucleotide polymorphisms (SNPs).</p

Correlation between ΔΔCt and absolute number of DNA copies of LPA exon 4.

<p>The C27 sample, previously predicted to have 27 DNA copies of this region, has been used as reference.</p