61 research outputs found
Mass spectrometry characterization of the glycation sites of bovine insulin by tandem mass spectrometry
Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics
Cardiovascular disease is a common complication of diabetes and the leading cause of death among people with diabetes. Because of the huge premature morbidity and mortality associated with diabetes, prevention of vascular complications is a key issue. Although the exact mechanism by which vascular damage occurs in diabetes in not fully understood, numerous studies support the hypothesis of a causal relationship of non-enzymatic glycation with vascular complications. In this review, data which point to an important role of Amadori-modified glycated proteins and advanced glycation endproducts in vascular disease are surveyed. Because of the potential role of early- and advanced non-enzymatic glycation in vascular complications, we also described recent developments of pharmacological inhibitors that inhibit the formation of these glycated products or the biological consequences of glycation and thereby retard the development of vascular complications in diabetes
Overestimation of Glucose in Uranyl Acetate-Treated Samples: Modification of the Deproteinization Method
Mikrobestimmung von Glucose mit Glucosedehydrogenase bei bestimmungsunabhängiger Probenvorbereitung im Routinelaboratorium
Peer Reviewe
Mikrobestimmung von Glucose mit Glucosedehydrogenase bei bestimmungsunabhängiger Probenvorbereitung im Routinelaboratorium
Matrix-assisted laser desorption/ionization mass spectrometry, enzymatic digestion, and molecular modeling in the study of nonenzymatic glycation of IgG
Possible Significance of Advanced Glycation End Products in Serum in End-Stage Renal Disease and in Late Complications of Diabetes
- …