The Administrative-Territorial Boundaries Available for a Multiscalar Analysis of EU Port Cities

Using various administrative-territorial boundaries, inhabitants, and businesses as nodes, port cities in the European Union (EU) could be analysed on multiple scales using a network method that takes into account the most important criteria (transport, population, and economy) for measuring the urban and port functions. The possible beneficiaries of such a methodology are policymakers who can aid municipalities in resolving problems in port cities. Thus, this study aimed to pinpoint existing port city policy domains that can be impacted by such a methodology and make corresponding recommendations. The policy domains identified in most port cities (port, port-city, and transportation policies) were matched with the three criteria established by the methodology. Study findings indicate that the proposed network methodological approach can impact upon the internal and external configuration urban and spatial policies. Also, it can impact their related policy instruments because they should be selected in light of the port city’s current state.Folosind diversele limite administrativteritoriale, locuitorii, și firmele ca noduri, orașele portuare din UE ar putea fi analizate multiscalar printr-o metodologie ce utilizează rețeaua ca instrument de analiză și cele mai importante criterii (transportul, populația, și economia) pentru măsurarea funcțiilor urbane și portuare. Beneficiarii unei astfel de metodologii ar putea fi elaboratorii de politici care pot ajuta municipalitățile să rezolve problemele cu care se confruntă orașele portuare. Astfel că, acest studiu a avut ca scop identificarea politicilor orașelor portuare ce pot fi afectate de o astfel de abordare metodologică și formularea unor recomandări corespunzătoare. Politicile identificate în majoritatea orașelor portuare (politicile portuare, orașului-port, și de transport) au fost consultate și corelate cu cele trei criterii stabilite de metodologie. Concluziile acestui studiu indică faptul că abordarea metodologică propusă poate să aibă un impact asupra configurației interne și externe a politicilor urbane și spațiale. În plus, poate să aibă un impact asupra instrumentelor aferente politicilor, deoarece acestea ar trebui stabilite pe baza stării actuale a orașului portuar analizat

MS

thesisThe propagation of WEE virus variants L.P. #7 and S.P. #6 infected chick embryo cells maintained as monolayer and in suspension was studied at 25° and 37°C. The results may be summarized as follows: 1. The lag-period of the growth cycle for L.P. #6 and S.P. #7 was found to be 10 hours when the infected cells were maintained as a monolayer or in suspension and incubated at 25°C. The lag period for S.P. #6 infected cells in suspension and as a monolayer incubated at 37° was found to be 2 hours while that for L.P. #7 was 1 ½ hours. 2. The maximum number of PFU in both variants present in the extracellular fluid was reached after 72 hours of incubation of infected monolayers at 25°C. With S.P, #6 infected cells in suspension the maximum titer of S.P. #6 PFU was attained after 48 hours of incubation at 25°C while with L.P. #7 infected cells the maximum PFU was reached after only 36 hours of incubation at 25°C. S.P. #6 infected cell in suspension, however, released a larger number of PFU than did L.P. #7 infected cells. The reverse was true with cells maintained as a monolayer. 3. The maximum number of PFU released into the extracellular fluid by S.P. #6 and L.P. #7 infected cells in suspension or maintained as a monolayer occurred after 10 hours of incubation at 37°C. The highest titer was produced by cell infected with the large plaque variant. 4. On the basis of infective center assay and counts of replicate non-infected monolayers the number of PFU released per infected cell was determined. An experiment was designed to study the cytopathic changes that develop in WEE virus infected chick embryo cells incubated at 25°C and 37°C. the results of this experiment may be summarized as follows: 1. Cytopathogenicity was first observed in L.P. #7 infected cells after 8 hours of incubation at 37°C. S.P. #6 infected cell did not show definite signs of cytopathic changes until after 10 hours of incubation at 37°C. 2. Infected cells incubated at 25°C developed observable cytopathogenicity after 24 hours of incubation. 3. Comparisons were made with the development of cytopathogenicity and the propagation of the two variants at the two experimental temperatures

Ecotourism planning in a wetland of international importance and sustainable territorial development

Wetlands are complex ecosystems, which provide excellent conditions as habitats for numerous species. It has been known that continuous unsustainable urbanization negatively affects natural resources, especially wetlands. The study has underlined the need for proper planning in a wetland of international importance, as a key element in the development of a sustainable urban-rural scenario. This paper is a mixture of both inductive and deductive steps, which underline a case study based on the abductive method. The investigation consisted in analysing the ecotourism planning methods of several case studies and drawing a parallel between them and the study area, Old Danube-Măcin Arm, where this activity is not implemented. The key results show that ecotourism plays a crucial role in the sustainable development of an urban-rural area with the following properties: compact microregion and the adaptability of it to the challenges of the territory. Successful zoning and visitor management methods are used to mitigate the existing conflict between conservation of sensitive areas and the danger of exposing said areas to public use. Ecotourism, encouraged and managed by the community, becomes a way of consolidating the economic growth of the study area

The Effect of Shear Stress on the Von Willebrand Factor and its Implications in Infective Endocarditis Caused by Staphylococcus

Endocarditis is caused by destruction of heart valve tissue. Infective endocarditis (IE) results from damage caused by microorganisms. IE is a serious disease with a mortality rate of 40%. Even though first described in 1885, IE incidence and mortality rate remains unchanged. In fact, the incidence of IE caused by staphylococci infections has increased over the few past decades. Part of the increase is associated with advancement in healthcare technology like hemodialysis, prosthetic valves, and intracardiac devices and their ability to introduce potential infective sites. Treatment of this disease also has been impacted over the years. Resistance to antibiotics by treatment of staphylococcal strains has been growing. Increasing our understanding of the epidemiology of the bacteria that cause IE is vital. This paper will link our knowledge about the binding tendencies abilities of two IE causing staphylococcal strains, S. aureus and S. lugdunensis, and to what is known about immune cells using that same binding factor under shear stress. This correlation will be used to establish a hypothesis stating that the cleavage of the VWF under shear stress creates an opportunistic environment for S. aureus and S. lugdunensis target high shear force locations, as seen in IE, as another mechanism to evade elimination by the immune system and increase proliferation. No such link currently has been made

The meaning of research as inquiry for discovery and educational improvement

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