402 research outputs found
Primer Design to Sequence Analysis - a Pipeline for a Molecular Genetic Diagnostic Laboratory
Some Properties of the Computable Cross Norm Criterion for Separability
The computable cross norm (CCN) criterion is a new powerful analytical and
computable separability criterion for bipartite quantum states, that is also
known to systematically detect bound entanglement. In certain aspects this
criterion complements the well-known Peres positive partial transpose (PPT)
criterion. In the present paper we study important analytical properties of the
CCN criterion. We show that in contrast to the PPT criterion it is not
sufficient in dimension 2 x 2. In higher dimensions we prove theorems
connecting the fidelity of a quantum state with the CCN criterion. We also
analyze the behaviour of the CCN criterion under local operations and identify
the operations that leave it invariant. It turns out that the CCN criterion is
in general not invariant under local operations.Comment: 7 pages; accepted by Physical Review A; error in Appendix B correcte
Expansion and Diversification of Medical Education in Australia, 1951-2000
Australia's present diverse and dynamic medical education environment has been shaped by - university funding increases by governments in the 1960s and 1970s to promote Australia as the clever country - the Karmel report's recommendations of increases in student numbers, new medical schools and a community focus for medical education - the successful innovations in entrance requirements and curricula of the most recent medical schools - Newcastle and Flinders - the formation of the Australian Medical Council, with a mandate to replace the British General Medical Council's accreditation of and restrictions on Australian medical school courses - the Doherty report, which identified the close relationship between medical education, funding and workforce issues - the change to graduate entry and a four-year course for several Australian medical schools and - changing patterns of healthcare delivery, the imperative for increasing access to healthcare in rural areas and the communication revolution made possible by information technolog
Infrared Spectroscopy of a Massive Obscured Star Cluster in the Antennae Galaxies (NGC 4038/4039) with NIRSPEC
We present infrared spectroscopy of the Antennae Galaxies (NGC 4038/4039)
with NIRSPEC at the W. M. Keck Observatory. We imaged the star clusters in the
vicinity of the southern nucleus (NGC 4039) in 0.39" seeing in K-band using
NIRSPEC's slit-viewing camera. The brightest star cluster revealed in the
near-IR (M_K(0) = -17.9) is insignificant optically, but coincident with the
highest surface brightness peak in the mid-IR (12-18 micron) ISO image
presented by Mirabel et al. (1998). We obtained high signal-to-noise 2.03 -
2.45 micron spectra of the nucleus and the obscured star cluster at R ~ 1900.
The cluster is very young (4 Myr old), massive (16e6 M_sun), and compact
(density ~ 115 M_sun pc^(-3) within a 32 pc half-light radius), assuming a
Salpeter IMF (0.1 - 100 M_sun). Its hot stars have a radiation field
characterized by T_eff ~ 39,000 K, and they ionize a compact H II region with
n_e ~ 1e4 cm^(-3). The stars are deeply embedded in gas and dust (A_V ~ 9-10
mag), and their strong FUV field powers a clumpy photodissociation region with
densities n_H >= 1e5 cm^(-3) on scales of up to 200 pc, radiating L[H_2 1-0
S(1)] = 9600 L_sun.Comment: 4 pages, 5 embedded figures. To appear in proceedings of 33d ESLAB
Symposium: Star Formation from the Small to the Large Scale, held in
Noordwijk, The Netherlands, Nov. 1999. Also available at
http://astro.berkeley.edu/~agilber
Postmortem DNA: QC Considerations for Sequence and Dosage Analysis of Genes Implicated in Long QT Syndrome
Design and operation of automated ice-tethered profilers for real-time seawater observations in the polar oceans
An automated, easily-deployed Ice-Tethered Profiler (ITP) has been developed for deployment on perennial sea ice in polar oceans to
measure changes in upper ocean temperature and salinity in all seasons. The ITP system consists of three components: a surface
instrument that sits atop an ice floe, a weighted, plastic-jacketed wire-rope tether of arbitrary length (up to 800 m) suspended from the
surface instrument, and an instrumented underwater unit that profiles up and down the wire tether. The profiling underwater unit is
similar in shape and dimension to an ARGO float except that the float's variable-buoyancy system is replaced with a traction drive unit.
Deployment of ITPs may be conducted either from ice caps or icebreakers, utilizing a self contained tripod/winch system that requires no
power. Careful selection of an appropriate multiyear ice floe is needed to prolong the lifetime of the system (up to 3 years depending on
the profiling schedule). Shortly after deployment, each ITP begins profiling the water column at its programmed sampling interval. After
each acquired temperature and salinity profile, the underwater unit (PROCON) transfers the data and engineering files using an inductive
modem to the surface controller (SURFCON). SURFCON also accumulates battery voltages, buoy temperature, and locations from GPS at
specified intervals in status files, and queues that information for transmission at the start of each new day. At frequent intervals, an
Iridium satellite transceiver in the surface package calls and transmits queued status and CTD data files onto a WHOI logger computer,
which are subsequently processed and displayed in near-real time at http://www.whoi.edu/itp. In 2004 and 2005, three ITP prototypes
were deployed in the Arctic Ocean. Each system was programmed with accelerated sampling schedules of multiple one-way traverses per
day between 10 and 750-760 m depth in order to quickly evaluate endurance and component fatigue. Two of the ITPs are continuing to
function after more than 10 months and 1200 profiles. Larger motor currents are observed at times of fast ice floe motion when larger
wire angles develop and drag forces on the profiler are increased. The CTD profile data so far obtained document interesting spatial
variations in the major water masses of the Beaufort Gyre, show the double-diffusive thermohaline staircase that lies above the warm,
salty Atlantic layer, and many mesoscale eddys. Deployed together with CRREL Ice Mass Balance (IMB) buoys, these ITP systems also
operate as part of an Ice Based Observatory (IBO). Data returned from an array of IBOs within an Arctic Observing Network will provide
valuable real time observations, support studies of ocean processes, and facilitate numerical model initialization and validation.Funding was provided by the National Science Foundation under Contract Nos. OCE-0324233 and ARC-0519899
Sexual counseling for individuals with cardiovascular disease and their partners: A consensus document from the american heart association and the esc council on cardiovascular nursing and allied professions (CCNAP)
Faithful Squashed Entanglement
Squashed entanglement is a measure for the entanglement of bipartite quantum
states. In this paper we present a lower bound for squashed entanglement in
terms of a distance to the set of separable states. This implies that squashed
entanglement is faithful, that is, strictly positive if and only if the state
is entangled. We derive the bound on squashed entanglement from a bound on
quantum conditional mutual information, which is used to define squashed
entanglement and corresponds to the amount by which strong subadditivity of von
Neumann entropy fails to be saturated. Our result therefore sheds light on the
structure of states that almost satisfy strong subadditivity with equality. The
proof is based on two recent results from quantum information theory: the
operational interpretation of the quantum mutual information as the optimal
rate for state redistribution and the interpretation of the regularised
relative entropy of entanglement as an error exponent in hypothesis testing.
The distance to the set of separable states is measured by the one-way LOCC
norm, an operationally-motivated norm giving the optimal probability of
distinguishing two bipartite quantum states, each shared by two parties, using
any protocol formed by local quantum operations and one-directional classical
communication between the parties. A similar result for the Frobenius or
Euclidean norm follows immediately. The result has two applications in
complexity theory. The first is a quasipolynomial-time algorithm solving the
weak membership problem for the set of separable states in one-way LOCC or
Euclidean norm. The second concerns quantum Merlin-Arthur games. Here we show
that multiple provers are not more powerful than a single prover when the
verifier is restricted to one-way LOCC operations thereby providing a new
characterisation of the complexity class QMA.Comment: 24 pages, 1 figure, 1 table. Due to an error in the published
version, claims have been weakened from the LOCC norm to the one-way LOCC
nor
Advancing translational research with the Semantic Web
<p>Abstract</p> <p>Background</p> <p>A fundamental goal of the U.S. National Institute of Health (NIH) "Roadmap" is to strengthen <it>Translational Research</it>, defined as the movement of discoveries in basic research to application at the clinical level. A significant barrier to translational research is the lack of uniformly structured data across related biomedical domains. The Semantic Web is an extension of the current Web that enables navigation and meaningful use of digital resources by automatic processes. It is based on common formats that support aggregation and integration of data drawn from diverse sources. A variety of technologies have been built on this foundation that, together, support identifying, representing, and reasoning across a wide range of biomedical data. The Semantic Web Health Care and Life Sciences Interest Group (HCLSIG), set up within the framework of the World Wide Web Consortium, was launched to explore the application of these technologies in a variety of areas. Subgroups focus on making biomedical data available in RDF, working with biomedical ontologies, prototyping clinical decision support systems, working on drug safety and efficacy communication, and supporting disease researchers navigating and annotating the large amount of potentially relevant literature.</p> <p>Results</p> <p>We present a scenario that shows the value of the information environment the Semantic Web can support for aiding neuroscience researchers. We then report on several projects by members of the HCLSIG, in the process illustrating the range of Semantic Web technologies that have applications in areas of biomedicine.</p> <p>Conclusion</p> <p>Semantic Web technologies present both promise and challenges. Current tools and standards are already adequate to implement components of the bench-to-bedside vision. On the other hand, these technologies are young. Gaps in standards and implementations still exist and adoption is limited by typical problems with early technology, such as the need for a critical mass of practitioners and installed base, and growing pains as the technology is scaled up. Still, the potential of interoperable knowledge sources for biomedicine, at the scale of the World Wide Web, merits continued work.</p
- …