13 research outputs found

    Association of Accelerometry-Measured Physical Activity and Cardiovascular Events in Mobility-Limited Older Adults: The LIFE (Lifestyle Interventions and Independence for Elders) Study.

    Get PDF
    BACKGROUND:Data are sparse regarding the value of physical activity (PA) surveillance among older adults-particularly among those with mobility limitations. The objective of this study was to examine longitudinal associations between objectively measured daily PA and the incidence of cardiovascular events among older adults in the LIFE (Lifestyle Interventions and Independence for Elders) study. METHODS AND RESULTS:Cardiovascular events were adjudicated based on medical records review, and cardiovascular risk factors were controlled for in the analysis. Home-based activity data were collected by hip-worn accelerometers at baseline and at 6, 12, and 24 months postrandomization to either a physical activity or health education intervention. LIFE study participants (n=1590; age 78.9±5.2 [SD] years; 67.2% women) at baseline had an 11% lower incidence of experiencing a subsequent cardiovascular event per 500 steps taken per day based on activity data (hazard ratio, 0.89; 95% confidence interval, 0.84-0.96; P=0.001). At baseline, every 30 minutes spent performing activities ≥500 counts per minute (hazard ratio, 0.75; confidence interval, 0.65-0.89 [P=0.001]) were also associated with a lower incidence of cardiovascular events. Throughout follow-up (6, 12, and 24 months), both the number of steps per day (per 500 steps; hazard ratio, 0.90, confidence interval, 0.85-0.96 [P=0.001]) and duration of activity ≥500 counts per minute (per 30 minutes; hazard ratio, 0.76; confidence interval, 0.63-0.90 [P=0.002]) were significantly associated with lower cardiovascular event rates. CONCLUSIONS:Objective measurements of physical activity via accelerometry were associated with cardiovascular events among older adults with limited mobility (summary score >10 on the Short Physical Performance Battery) both using baseline and longitudinal data. CLINICAL TRIAL REGISTRATION:URL: http://www.clinicaltrials.gov. Unique identifier: NCT01072500

    Cavioids, chinchilloids, and erethizontoids (Hystricognathi, Rodentia, Mammalia) of the early Miocene Pampa Castillo fauna, Chile (American Museum novitates, no. 3984)

    No full text
    46 pages : illustrations (some color) ; 26 cm.Caviomorph rodents became important components of South American faunas after their Eocene arrival from Africa. Here we describe the cavioid, chinchilloid, and erethizontoid caviomorphs of the early Miocene Pampa Castillo fauna of southern Chile. This fauna’s age and location make it key for resolving outstanding biostratigraphic questions concerning early Miocene Patagonian fossiliferous strata. Each of the four major caviomorph clades (“superfamilies”) is represented in the Pampa Castillo fauna, three whose members are detailed here: cavioids (3 genera; 3 species), chinchilloids (3 genera; 6 species), and erethizontoids (2 genera; 2 species). Abundantly represented taxa, e.g., Neoreomys australis, Perimys erutus, and Prolagostomus pusillus, corroborate previous work assigning the Pampa Castillo fauna to the Santacrucian South American Land Mammal “Age” (SALMA; inclusive of the “Pinturan”). Several taxa, including Eosteiromys, Perimys intermedius, and Perimys sp. nov.?, are also found in the lower and middle Pinturas Formation (lmPF) but not “core” Santacrucian faunas (from the Santa Cruz Formation [SCF] along the Río Santa Cruz and Atlantic coast), suggesting a distinctive resemblance between lmPF and Pampa Castillo rodents. Some authors consider the fauna from the lmPF to form the basis of a “Pinturan” SALMA or subage, considered to slightly predate core Santacrucian faunas, but which has yet to be formally recognized. The taxonomic composition of rodent fauna from Pampa Castillo, as well as relative abundance data, indicated a paleoenvironment intermediate between the closed forests of the lmPF and the mosaic of open and closed habitats of the core Santacrucian faunas from the SCF

    Proceedings from the 9th annual conference on the science of dissemination and implementation

    No full text
    corecore