3,128 research outputs found
Infected epidermal cyst of the clitoris in an infant
Clitoral enlargement in the pediatric population is a rare condition, usually related to problems of sexual differentiation, but malignant and benign clitoral lesions have also been described. We report the case of a newborn infant, investigated at birth for an intersex disorder because of clitoromegaly. Hormonal screening was normal and ultrasound (US) did not show a pelvic or abdominal mass. Three weeks later, the lesion was larger, tense and erythematous. An abscess was suspected. A drainage was then performed, and the bacteriological culture revealed the presence of Staphylococci aurei. A magnetic resonance imaging (MRI) performed to exclude a tumor of the soft tissue was normal. A diagnosis of infected epidermal cyst was confirmed by the pathology. Two months later, the external genital aspect was normal and the child asymptomatic
CLASS Survey Description: Coronal Line Needles in the SDSS Haystack
Coronal lines are a powerful, yet poorly understood, tool to identify and
characterize Active Galactic Nuclei (AGNs). There have been few large scale
surveys of coronal lines in the general galaxy population in the literature so
far. Using a novel pre-selection technique with a flux-to-RMS ratio ,
followed by Markov-Chain Monte Carlo (MCMC) fitting, we searched for the full
suite of 20 coronal lines in the optical spectra of almost 1 million galaxies
from the Sloan Digital Sky Survey (SDSS) Data Release 8. We present a catalog
of the emission line parameters for the resulting 258 galaxies with detections.
The Coronal Line Activity Spectroscopic Survey (CLASS) includes line
properties, host galaxy properties, and selection criteria for all galaxies in
which at least one line is detected. This comprehensive study reveals that a
significant fraction of coronal line activity is missed in past surveys based
on a more limited set of coronal lines; 60% of our sample do not display
the more widely surveyed [Fe X] 6374. In addition, we discover a
strong correlation between coronal line and WISE W2 luminosities, suggesting
that the mid-infrared flux can be used to predict coronal line fluxes. For each
line we also provide a confidence level that the line is present, generated by
a novel neural network, trained on fully simulated data. We find that after
training the network to detect individual lines using 100,000 simulated
spectra, we achieve an overall true positive rate of 75.49% and a false
positive rate of only 3.96%.Comment: 27 pages, 16 figures, 4 table
An introduction to crowdsourcing for language and multimedia technology research
Language and multimedia technology research often relies on
large manually constructed datasets for training or evaluation of algorithms and systems. Constructing these datasets is often expensive with significant challenges in terms of recruitment of personnel to carry out the work. Crowdsourcing methods using scalable pools of workers available on-demand offers a flexible means of rapid low-cost construction of many of these datasets to support existing research requirements and potentially promote new research initiatives that would otherwise not be possible
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Novel Secretion Apparatus Maintains Spore Integrity and Developmental Gene Expression in Bacillus subtilis
Sporulation in Bacillus subtilis involves two cells that follow separate but coordinately regulated developmental programs. Late in sporulation, the developing spore (the forespore) resides within a mother cell. The regulation of the forespore transcription factor σG that acts at this stage has remained enigmatic. σG activity requires eight mother-cell proteins encoded in the spoIIIA operon and the forespore protein SpoIIQ. Several of the SpoIIIA proteins share similarity with components of specialized secretion systems. One of them resembles a secretion ATPase and we demonstrate that the ATPase motifs are required for σG activity. We further show that the SpoIIIA proteins and SpoIIQ reside in a multimeric complex that spans the two membranes surrounding the forespore. Finally, we have discovered that these proteins are all required to maintain forespore integrity. In their absence, the forespore develops large invaginations and collapses. Importantly, maintenance of forespore integrity does not require σG. These results support a model in which the SpoIIIA-SpoIIQ proteins form a novel secretion apparatus that allows the mother cell to nurture the forespore, thereby maintaining forespore physiology and σG activity during spore maturation
Whole-genome characterisation of G12P[6] rotavirus strains possessing two distinct genotype constellations co-circulating in Blantyre, Malawi, 2008
Early Career Perspectives For the NASA SMD Bridge Program
In line with the Astro2020 Decadal Report State of the Profession findings
and the NASA core value of Inclusion, the NASA Science Mission Directorate
(SMD) Bridge Program was created to provide financial and programmatic support
to efforts that work to increase the representation and inclusion of students
from under-represented minorities in the STEM fields. To ensure an effective
program, particularly for those who are often left out of these conversations,
the NASA SMD Bridge Program Workshop was developed as a way to gather feedback
from a diverse group of people about their unique needs and interests. The
Early Career Perspectives Working Group was tasked with examining the current
state of bridge programs, academia in general, and its effect on students and
early career professionals. The working group, comprised of 10 early career and
student members, analyzed the discussions and responses from workshop breakout
sessions and two surveys, as well as their own experiences, to develop specific
recommendations and metrics for implementing a successful and supportive bridge
program. In this white paper, we will discuss the key themes that arose through
our work, and highlight select recommendations for the NASA SMD Bridge Program
to best support students and early career professionals.Comment: White paper developed by the Early Career Perspectives Working Group
for the NASA SMD Bridge Program Workshop. 11 page
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