638 research outputs found
Fixing the leak: Unemployment incidence before and after the 2006 reform of unemployment benefits in Germany
"From 2002 - 2004, the German government passed several laws that curtailed the generosity of the unemployment compensation system. One of the most ambitious changes was a considerable reduction in unemployment benefit entitlement lengths for older unemployed, which was effective during 2006 and 2007. We apply a difference-in-differences approach to show that the highly disputed reform induced a considerable decline in unemployment incidence among older workers. It thus sealed an important leak in the unemployment insurance system. Furthermore, we find a strong anticipation effect; unemployment entries of elderly workers peaked during the months preceding the reform." (Author's abstract, IAB-Doku) ((en))ältere Arbeitnehmer, arbeitsmarktpolitische Maßnahme, Arbeitslosengeld, Leistungsbezug - Dauer, Wirkungsforschung
Fixing the leak: unemployment incidence before and after the 2006 reform of unemployment benefits in Germany
From 2002-2004, the German government passed several laws that curtailed the generosity of the unemployment compensation system. One of the most ambitious changes was a considerable reduction in unemployment benefit entitlement lengths for older unemployed, which was effective during 2006 and 2007. We apply a difference-in-differences approach to show that the highly disputed reform induced a considerable decline in unemployment incidence among older workers. It thus sealed an important leak in the unemployment insurance system. Furthermore, we find a strong anticipation effect; unemployment entries of elderly workers peaked during the months preceding the reform. --unemployment incidence,policy evaluation,administrative data
The sorting of female careers after first birth : a competing risks analysis of maternity leave duration
A number of contributions have found evidence for motherhood being a critical life
event for women's employment careers. This study presents a detailed model for the du-
ration of maternity leave in which young mothers can make a transition into a number of
states related to employment and unemployment among others. The model incorporates
a large number of factors including the legal framework, individual and firm character-
istics. We provide a comprehensive picture of the sorting mechanisms that lead to the
differentiation of women's employment careers after birth. Our empirical evidence is de-
rived from large linked administrative individual labour market data from Germany for a
period of three decades. We obtain unprecedented insights how women's skills, the quality
of the previous job match, firm level characteristics, labour market conditions and leave
legislation are related to the length of maternity duration
Fixing the leak: unemployment incidence before and after the 2006 reform of unemployment benefits in Germany
"Das Gesetz zu Reformen am Arbeitsmarkt schränkte ab Februar 2006 die Bezugshöchstdauern des Arbeitslosengeldes für Ältere stark ein; je nach Altersgruppe um bis zu 14 Monate. Wir untersuchen dieses natürliche Experiment und zeigen: Bei den betroffenen Altersgruppen stiegen die Übergangsraten aus Beschäftigung in Arbeitslosigkeit in den drei Monaten vor der Reform deutlich an: Bei einem durchschnittlichen Arbeitnehmer der Altersgruppe 57 bis 64 war die monatliche Übergangswahrscheinlichkeit sogar um etwa 120 Prozent höher, als ohne Reform zu erwarten gewesen wäre. Im Nachreform-Zeitraum bis Ende 2007 sanken die monatlichen Eintrittsraten Älterer in Arbeitslosigkeit deutlich ab; sie lagen bei den 57-64 Jährigen um gut 20 Prozent niedriger als ohne Reform. Ein Teil der geringeren Eintritte im Nachreform-Zeitraum dürfte darauf zurückzuführen sein, dass Übergänge in die Monate vor der Reform vorgezogen wurden. Da der Gesetzgeber die Bezugshöchstdauern bereits Anfang 2008 teils wieder verlängerte, lässt sich der exakte langfristige Reformeffekt leider nicht identifizieren." (Autorenreferat)"From 2002-2004, the German government passed several laws that curtailed the generosity of the unemployment compensation system. One of the most ambitious changes was a considerable reduction in unemployment benefit entitlement lengths for older unemployed, which was effective during 2006 and 2007. We apply a difference-in-differences approach to show that the highly disputed reform induced a considerable decline in unemployment incidence among older workers. It thus sealed an important leak in the unemployment insurance system. Furthermore, we find a strong anticipation effect; unemployment entries of elderly workers peaked during the months preceding the reform." (author's abstract
Fixing the leak : unemployment incidence before and after the 2006 reform of unemployment benefits in Germany
From 2002–2004, the German government passed several laws that curtailed the generosity of the unemployment compensation system. One of the most ambitious changes was a considerable reduction in unemployment benefit entitlement lengths for older unemployed, which was effective during 2006 and 2007. We apply a difference-in-differences approach to show that the highly disputed reform induced a considerable decline in unemployment incidence among older workers. It thus sealed an important leak in the unemployment insurance system. Furthermore, we find a strong anticipation effect; unemployment entries of elderly workers peaked during the months preceding the reform
Generalised partially linear regression with misclassified data and an application to labour market transitions
We consider the semiparametric generalised linear regression model which has mainstream
empirical models such as the (partially) linear mean regression, logistic and multinomial regression
as special cases. As an extension to related literature we allow a misclassified covariate to
be interacted with a nonparametric function of a continuous covariate. This model is tailormade
to address known data quality issues of administrative labour market data. Using a
sample of 20m observations from Germany we estimate the determinants of labour market
transitions and illustrate the role of considerable misclassification in the educational status on
estimated transition probabilities and marginal effects
Differentiation of Cultured Human Epidermal Keratinocytes at High Cell Densities is Mediated by Endogenous Activation of the Protein Kinase C Signaling Pathway
Normal human epidermal keratinocytes (NHEK) grown in serum-free medium on a plastic substrate spontaneously differentiate at high cell densities in vitro. Because protein kinase C (PKC) regulates murine keratinocyte differentiation triggered by a variety of stimuli, we examined the role of this signaling pathway in density-dependent activation of NHEK differentiation. Relative to subconfluent cultures, confluent NHEK expressed markedly higher levels of multiple differentiation markers assayed by immunoblotting, including keratin 1, loricrin, filaggrin, involucrin, TGK, and SPR-1. Expression of several of these markers continued to increase for several days after cells reached confluency. The total level of several PKC isoforms was not substantially altered in NHEK harvested at different cell densities, based on immunoblotting; however, subcellular fractionation revealed that PKCα underwent a redistribution to the particulate fraction in confluent and postconfluent NHEK cultures, suggesting that this isozyme was activated under these conditions and may be involved in triggering the terminal differentiation program. Supporting this concept, inhibition of PKC function using bryostatin 1 or GF 109203X blocked the induction of keratinocyte differentiation markers at high cell densities. These data suggest that endogenous activation of PKC is responsible for cell density-mediated stimulation of NHEK differentiation, establishing a critical role for this pathway in regulating human as well as murine keratinocyte differentiation
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Dual and opposing roles of primary cilia in medulloblastoma development.
Recent work has shown that primary cilia are essential for Hedgehog (Hh) signaling during mammalian development. It is also known that aberrant Hh signaling can lead to cancer, but the role of primary cilia in oncogenesis is not known. Cerebellar granule neuron precursors (GNPs) can give rise to medulloblastomas, the most common malignant brain tumor in children. The primary cilium and Hh signaling are required for GNP proliferation. We asked whether primary cilia in GNPs have a role in medulloblastoma growth in mice. Genetic ablation of primary cilia blocked medulloblastoma formation when this tumor was driven by a constitutively active Smoothened protein (Smo), an upstream activator of Hh signaling. In contrast, removal of cilia was required for medulloblastoma growth by a constitutively active glioma-associated oncogene family zinc finger-2 (GLI2), a downstream transcription factor. Thus, primary cilia are either required for or inhibit medulloblastoma formation, depending on the initiating oncogenic event. Remarkably, the presence or absence of cilia was associated with specific variants of human medulloblastomas; primary cilia were found in medulloblastomas with activation in HH or WNT signaling but not in most medulloblastomas in other distinct molecular subgroups. Primary cilia could serve as a diagnostic tool and provide new insights into the mechanism of tumorigenesis
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