Classification of samples submitted to MALDI-TOF MS and real-time PCR results.

<p>Classification of samples submitted to MALDI-TOF MS and real-time PCR results.</p

Result of the blind tests against the MALDI-TOF MS reference database according the compartment and infectious status of mosquitoes.

<p>Result of the blind tests against the MALDI-TOF MS reference database according the compartment and infectious status of mosquitoes.</p

Comparison of MALDI-TOF MS spectra from heads of <i>Aedes aegypti</i> infected or not by filariae.

<p>Spectra of control uninfected <i>Ae</i>. <i>aegypti</i> (A, B); infected with <i>B</i>. <i>malayi</i> (C, D) or <i>B</i>. <i>pahangi</i> (E, F). Some distinct protein masses generated with ClinProTools are represented (I, J and K). a.u., arbitrary units; m/z, mass-to-charge ratio.</p

Comparison of MALDI-TOF MS spectra from thorax-head of <i>Aedes aegypti</i> infected or not by filariae.

<p>Spectra of control uninfected <i>Ae</i>. <i>aegypti</i> (A, B); infected with <i>D</i>. <i>immitis</i> (C, D) or <i>B</i>. <i>malayi</i> (E, F) or <i>B</i>. <i>pahangi</i> (G, H). Somme distinct protein masses generated with ClinProTools are represented (I, J, K, and L). a.u., arbitrary units; m/z, mass-to-charge ratio.</p

Comparison of MALDI-TOF MS spectra from legs of <i>Aedes aegypti</i> infected or not by filariae.

<p>Spectra of control <i>Ae</i>. <i>aegypti</i> not exposed to filariae (A, B) or infected with <i>D</i>. <i>immitis</i> (C, D) or <i>B</i>. <i>malayi</i> (E, F) or <i>B</i>. <i>pahangi</i> (G, H). The filariae infectious status for each specimen was controlled by qPCR. Some distinct protein masses detected with ClinProTools software are represented (I, J, K, and L). a.u., arbitrary units; m/z, mass-to-charge ratio.</p

Peak masses distinguishing uninfected and filariae-infected <i>Aedes aegypti</i> mosquitoes according the compartment, based on the Genetic Algorithm model analysis of ClinProTools.

<p>Peak masses distinguishing uninfected and filariae-infected <i>Aedes aegypti</i> mosquitoes according the compartment, based on the Genetic Algorithm model analysis of ClinProTools.</p

Monthly collections of sand flies by light traps in 2015.

<p>Monthly collections of sand flies by light traps in 2015.</p

Primers and probes used for real time PCR and conventional PCR in this study.

<p>Primers and probes used for real time PCR and conventional PCR in this study.</p