2 research outputs found
Kaplan Meier survival analyses of patients with high (solid) and low (dashed) cell infiltration in the tumor
<p><b>Copyright information:</b></p><p>Taken from "Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survival"</p><p>http://www.translational-medicine.com/content/5/1/62</p><p>Journal of Translational Medicine 2007;5():62-62.</p><p>Published online 29 Nov 2007</p><p>PMCID:PMC2212626.</p><p></p> A) Patients with high S100 infiltration have a significantly better survival (p = 0.03). B) Patients with high total CD163 tend to have a better survival (p = 0.07). C) Patients with high stromal CD163 infiltration have a significantly better survival (p = 0.01)
Induction of gene expression by stimulation of LPS-activated MPs with IFN-γ and IL-4
<p><b>Copyright information:</b></p><p>Taken from "Polarized monocyte response to cytokine stimulation"</p><p>Genome Biology 2005;6(2):R15-R15.</p><p>Published online 21 Jan 2005</p><p>PMCID:PMC551535.</p><p>Copyright © 2005 Nagorsen et al.; licensee BioMed Central Ltd.</p> MPs obtained from PBMC from five normal donors were stimulated for 4 h with one cytokine representative of the alternative (IL-4) and one of the classical group (IFN-γ) and gene transcription measured by TaqMan real-time PCR. The relative quantification of 10 genes was calculated by normalizing the ratio of the mean copy number for each gene with the mean copy number of the reference AFAP gene in MPs from five donors. Statistically significant differences (-value < 0.05) between the two cytokine treatments as assessed by Student's -test are represented by an asterisk