Morphofunctional correlations in the experimental study of myocardiopathies under the stress of forced restraint. Note 2: The influence of adrenal imbalance

Tests were performed with 70 rats to determine the effects of restraint on the functions and structure of the myocardium under varying conditions of adrenal imbalance. Results showed that in rats with adrenal imbalance, fasting and restraint produced the same biochemical alterations as in the controls. The morphologic alteractions, as well as their electric expression, were more varied and evident in the animals with adrenal imbalance. Persistence of the microscopic and electrocardiographic alterations after 72 hours restraint in the animals subjected to unilateral adrenalectomy suggests chronic evolution of the myocardial lesions. This proves the necessity of intact adrenals for a good adaptability to stress

Measurements and TCAD simulation of novel ATLAS planar pixel detector structures for the HL-LHC upgrade

The LHC accelerator complex will be upgraded between 2020-2022, to the High-Luminosity-LHC, to considerably increase statistics for the various physics analyses. To operate under these challenging new conditions, and maintain excellent performance in track reconstruction and vertex location, the ATLAS pixel detector must be substantially upgraded and a full replacement is expected. Processing techniques for novel pixel designs are optimised through characterisation of test structures in a clean room and also through simulations with Technology Computer Aided Design (TCAD). A method to study non-perpendicular tracks through a pixel device is discussed. Comparison of TCAD simulations with Secondary Ion Mass Spectrometry (SIMS) measurements to investigate the doping profile of structures and validate the simulation process is also presented.Comment: 9 pages, 7 figures, PIXEL201

A review of maternal and fetal outcome of induction of labour with Foley’s catheter and extra amniotic saline infusion in women with previous caesarean delivery

Background: Incidence of induction of labour has increased in the recent past due to increased screening facilities like ante partum fetal surveillance. Vaginal birth after caesarean section (VBAC) is one of the strategies developed to control the rising rate of caesarean sections. Intracervical Foley’s catheter reduces the risk of uterus hyper tonicity and rupture in women with one caesarean section as it’s placement induces the cervical repining without inducing any uterine contractions.Methods: A prospective study of 35 women with one previous LCSs, term gestation and singleton pregnancy, were selected for trial of labour (TOL) considering inclusion and exclusion criteria.Results: Out of 35 cases studied 21 cases (60%) went for successful induction with Foleys and the remaining 40% underwent caesarean section. The mean time interval for Foley’s expulsion was 6.74 in the success group and 10.04 in the failed group (p value <0.05). In 4 cases there were meconium stained liquor, and they underwent emergency LSCS. One case (2.8%) had scar rupture which also underwent caesarean section.Conclusions: This study shows that the Foley catheter is an effective method of cervical ripening with additional benefit of low cost, reversibility, easy availability and lack of need for special storage. This method confers significant improvement in Bishop Score and vaginal delivery was achieved in majority of patients

Simulation of guard ring influence on the performance of ATLAS pixel detectors for inner layer replacement

Electric field magnitude and depletion in the bulk of silicon pixel detectors, which influence its breakdown behaviour, was studied using finite-element method to solve the drift-diffusion equation coupled to Poisson's equation in a simplified two dimensional model of the ATLAS pixel sensor. Based on this model, the number of guard rings and dead edges width were modified to investigate their influence on the detector's depletion at the edge and on its internal electrical field distribution. Final ly, the 3 level model was implemented into the simulation to study the behaviour of such detector under different level of irradiation

An Efficient Rank Based Approach for Closest String and Closest Substring

This paper aims to present a new genetic approach that uses rank distance for solving two known NP-hard problems, and to compare rank distance with other distance measures for strings. The two NP-hard problems we are trying to solve are closest string and closest substring. For each problem we build a genetic algorithm and we describe the genetic operations involved. Both genetic algorithms use a fitness function based on rank distance. We compare our algorithms with other genetic algorithms that use different distance measures, such as Hamming distance or Levenshtein distance, on real DNA sequences. Our experiments show that the genetic algorithms based on rank distance have the best results