Use of ATP bioluminescence for assessing the cleanliness of hospital surfaces: A review of the published literature (1990-2012)

Hospital cleanliness tends to be considered by patients and the public as an important indicator of the general quality of healthcare. Tests for detecting the presence of adenosine triphosphate (ATP) as a proxy of microbial contamination are increasing in popularity, and several studies have been conducted on this topic in the last few decades. The aim of the present study was to review the published literature on this topic and summarize and discuss the available results. The review focused on relevant English-language articles that were identified through searches of two databases [PubMed and Scopus (1990-2012)] by using the keywords "ATP", "bioluminescence", "hospital", and "surfaces". Twelve articles were included and analyzed. ATP measurements showed a wide variation, with values ranging from 0 to >500,000 relative light units (RLU)/s before cleaning and from 3 to 500,000. RLU/s after cleaning. ATP benchmarks used by authors ranged from 100 to 500. RLU/s. The percentage of surfaces exceeding the chosen cut-off limit showed a failure rate varying from 21.2% to 93.1% before cleaning and from 5.3% to 96.5% after cleaning. Although the use of ATP bioluminescence can be considered a quick and objective method for assessing hospital cleanliness, it appears to be still poorly standardized at both the national and international level. © 2013 King Saud Bin Abdulaziz University for Health Sciences

Integrating the geodesic equations in the Schwarzschild and Kerr space-times using Beltrami's "geometrical" method

We revisit a little known theorem due to Beltrami, through which the integration of the geodesic equations of a curved manifold is accomplished by a method which, even if inspired by the Hamilton-Jacobi method, is purely geometric. The application of this theorem to the Schwarzschild and Kerr metrics leads straightforwardly to the general solution of their geodesic equations. This way of dealing with the problem is, in our opinion, very much in keeping with the geometric spirit of general relativity. In fact, thanks to this theorem we can integrate the geodesic equations by a geometrical method and then verify that the classical conservation laws follow from these equations.Comment: 12 pages; corrected typos, journal-ref adde

ACCURACY AND PRECISION OF THE KINETIC ANALYSIS OF COUNTER MOVEMENT JUMP PERFORMANCE

The purpose of this study was to quantify the accuracy and precision of measuring counter movement jump (CMJ) performance kinetically (i.e. measuring impulse using a force plate). A 14-camera 3D motion analysis system and a force plate were used simultaneously to obtain vertical trajectories of centre of mass (CM) for comparison. Fifty-eight CMJs were analyzed from eleven physically active males. Jump height differences were trivial, and small bias was obtained thereby showing good accuracy as well as small typical errors for performance. Our study indicates that force plates can be used confidently for CMJ analysis

Monoamine receptor interaction profiles of 4-thio-substituted phenethylamines (2C-T drugs)

4-Thio-substituted phenethylamines (2C-T drugs) are potent psychedelics with poorly defined pharmacological properties. Because of their psychedelic effects, 2C-T drugs are sometimes sold as new psychoactive substances (NPSs). The aim of the present study was to characterize the monoamine receptor and transporter interaction profiles of a series of 2C-T drugs.; We determined the binding affinities of 2C-T drugs at monoamine receptors and transporters in human cells that were transfected with the respective receptors or transporters. We also investigated the functional activation of serotonergic 5-hydroxytryptamine 2A (5-HT2A) and 5-HT2B receptors, activation of human trace amine-associated receptor 1 (TAAR1), and inhibition of monoamine uptake transporters.; 2C-T drugs had high affinity for 5-HT2A and 5-HT2C receptors (1-54 nM and 40-350 nM, respectively). With activation potencies of 1-53 nM and 44-370 nM, the drugs were potent 5-HT2A receptor and 5-HT2B receptor, respectively, partial agonists. An exception to this were the benzylthiophenethylamines, which did not potently activate the 5-HT2B receptor (EC50 > 3000 nM). Furthermore, the compounds bound to serotonergic 5-HT1A and adrenergic receptors. The compounds had high affinity for the rat TAAR1 (5-68 nM) and interacted with the mouse but not human TAAR1. The 2C-T drugs did not potently interact with monoamine transporters (Ki > 4000 nM).; The receptor binding profile of 2C-T drugs predicts psychedelic effects that are mediated by potent 5-HT2 receptor interactions

Assessing the impact of occupant behaviour on the electricity consumption for lighting and small power in office buildings

Lighting and small power will typically account for more than half of the total electricity consumption in an office building. Significant variations in electricity used by different tenants suggest that occupants can have a significant impact on the electricity demand for these end-uses. Yet current modelling techniques fail to represent the interaction between occupant and the building environment in a realistic manner. Understanding the impact of such behaviours is crucial to improve the methodology behind current energy modelling techniques, aiming to minimise the significant gap between predicted and in-use performance of buildings. A better understanding of the impact of occupant behaviour on electricity consumption can also inform appropriate energy saving strategies focused on behavioural change. This paper reports on a study aiming to assess the intent of occupants to switch off lighting and appliances when not in use in office buildings. Based on the Theory of Planned Behaviour, the assessment takes the form of a questionnaire and investigates three predictors to behaviour individually: 1) behavioural attitude; 2) subjective norms; 3) perceived behavioural control. The paper details the development of the assessment procedure and discusses preliminary findings from the study. The questionnaire results are compared against electricity consumption data for individual zones within a multi-tenanted office building. Initial results demonstrate a statistically significant correlation between perceived behavioural control and energy consumption for lighting and small powe

CENTRE OF PRESSURE DURING COUNTERMOVEMENT JUMP: IS IT RELATED TO EXPERTISE OR PERFORMANCE?

The purpose of this study was to investigate how specific variables related to the centre of pressure (CoP) trajectory during a countermovement jump (CMJ) carry information related to expertise and performance. The variables investigated were: lengths and average velocities during eccentric (Ecc) and concentric (Con) phases, medio-lateral (ML) and antero-posterior (AP) ranges of movement, and ML bias. In terms of expertise, the curves were tracked and compared over four jump sessions conducted by both experienced and inexperienced jumpers to investigate adaptive changes towards a more efficient way of jumping. Links between performance and those characteristics were also investigated. Our study indicated that no useful information related to either expertise or performance can be extracted from the CoP trajectory during a CMJ

Knowledge, risk perception and behaviours in swimming pool users of Palermo city, Sicily

To assess knowledge, risk perception and behaviours of a sample of swimming pool users in Palermo. A total of 498 subjects were interviewed by self-administered anonymous questionnaire including socio-demographic questions, knowledge/risk perception and behaviours. Overall, 289 subjects (58%) had a mean of 1.9\ub11.2 healthy behaviours. Age older than 30 years (OR=0.46; 95% CI=0.26\u20130.81), female sex (OR=0.52; 95% CI=0.35\u20130.76) and a high knowledge score (OR=0.15; 95% CI=0.03\u20130.69) were significantly associated with having healthy behaviours in both univariate and multivariate analysis. Unhealthy behaviours can be frequently found in swimming pool bathers and, particularly, in some target groups. Public health prevention strategies should be implemented to improve public awareness and information on a safe use of recreational water environments