94 research outputs found

    Linear and nonlinear waves in surface and wedge index potentials

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    We study optical beams that are supported at the surface of a medium with a linear index potential and by a piecewise linear wedge type potential. In the linear limit the modes are described by Airy functions. In the nonlinear regime we find families of solutions that bifurcate from the linear modes and study their stability for both self-focusing and self-defocusing Kerr nonlinearity. The total power of such nonlinear waves is finite without the need for apodization

    Cutaneous Manifestations in Patients with SARS- CoV-2 Infections

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    While SARS-CoV-2 is known to cause pneumonia and acute respiratory distress syndrome (ARDS), many extrapulmonary manifesta- tions of COVID-19 have also been observed. Cutaneous manifestations including erythematous rash, urticaria, and chickenpox-like vesicles have been described in patients with SARS-CoV-2. Six patients, two men and four women, in the age group of 50 to 60 years old, hospitalized with SARS-CoV-2 infection confirmed with real-time polymerase chain reac- tion (real-time PCR) presented cutaneous manifestations. The rash was confluent, spotty, centrifugal, and non-itchy on the head and torso. It was not hemorrhagic, and no crust or blisters were observed. The results of laboratory tests were normal, and the rash disappeared on its own. Sev- eral cases of cutaneous manifestations have been reported in patients with SARS-CoV-2 infection. Further studies are needed in order to assess the skin lesions and determine their association with COVID-19

    SARSCOV-2 PSYCHOSOMATIC EFFECTS AND FEAR OF STIGMA ON THE DISCHARGE DAY OF INFECTED INDIVIDUALS: SAPFO STUDY

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    Background: Although research has been mainly focused on effective treatment for SARS-COV-2 infection, psychosocial aspects of the infection it is vital to be taken into consideration. The aim of the present study is to evaluate the psychosomatic effects and the fear of stigma which patients may face after the end of treatment and discharge from hospital. Subjects and methods:This was a non-intervention perspective study conducted in the Department of Infectious Diseases of University General Hospital of Alexandroupolis (Greece). Patients on the discharge day completed questionnaires in which 5 topics were evaluated: pain/discomfort, anxiety/distress, fear/worries, stigma and tolerance of treatment. The questionnaires were derived from similar Quality of Life Tools. The total score of each patient was normalized as percentage. Results: Females and younger than 40 years old had more worries and fears on discharge day. Significant factors were days of hospitalization, days of fever and need of oxygen therapy. Patients who hospitalized more than 10 days, particularly in isolation negative pressure rooms, with persistent fever more than 7 days and need of oxygen therapy had more anxiety, worries for their clinical condition and fear of stigma. The majority of patients (80%) were expecting to face moderate to severe problems with family members, friends and colleagues underlying the dimensions of stigma. Conclusions: It is crucial to evaluate the psychosocial aspects of this infection and limit the stigma which patients may face returning to their daily routine. Further studies are needed with larger patient series and with the usage of psychometric instruments

    High-energy polarized electron beams from the ionization of isolated spin polarized hydrogen atoms

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    We propose a laser-based method for the preparation of high-energy, highly-polarized electrons, from the ionization of isolated spin-polarized hydrogen (SPH) atoms. The SPH atoms are prepared from the photodissociation of HBr, using two consecutive shaped UV pulses of ps duration. By appropriately timing and focusing the pulses, we can spatially separate the highly polarized SPH from other unwanted photoproducts, which then act as the target for the ion-acceleration lasers. The density of SPH can surpass \approx1018^{18} cm3^{-3}, allowing the production of GeV electrons with polarization larger than 90%

    Conflict Resilience

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    Although large-scale wars and interstate conflicts have almost disappeared, intrastate conflicts remain widespread and result in a high number of victims. During the last ten years, the number of fatalities was substantially higher than in the previous decade. Though these conflicts take place outside the borders of the EU, they can generate important direct and indirect effects. Moreover, they are connected to climate change, can lead to various disasters, geopolitical effects, or material supply disruptions. The concept of resilience has recently gained ground as a framework for addressing contemporary global threats. It has also become the key principle in the EU’s external action. One of its key building blocks is the modelling and monitoring of conflict risk to allow early action. Conflict resilience refers to the capacity of a state to resist a drift towards violence contrary to the structural conditions prevailing (pre-conflict resilience). It also includes the response of a state in the presence of a conflict (post-conflict resilience). Evaluating the pre-conflict resilience of states can provide insights into conflict aversion or enable a warning for the eruption of violence. On the other hand, the study of postconflict resilience may unveil the adaptive and transformative mechanisms that can be followed by other war-torn countries. Climate change and conflicts are closely related. For example, climate change exacerbates current conflict drivers like food insecurity, competition for water and land resources, poverty and internal displacement of people. Adaptation and mitigation policies may lead to new regulations or infrastructures (like new hydropower reservoirs) which can generate tensions and eventually conflicts. Finally, conflict-torn countries are unable to invest in adaptation strategies, which makes them even more vulnerable to climate change effects.JRC.E.1-Disaster Risk Managemen

    In the Footsteps of Scribonius Largus, a Pioneer of Clinical Pharmacy in Ancient Rome

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    Clinical pharmacy involves pharmacists in direct patient care concerning optimizing medicines and promoting health awareness and disease prevention. The whereabouts of the field can be traced to Scribonius Largus, a renowned physician and pharmacist in ancient Rome. Although Largus served as an imperial physician, he has also been an exemplary pharmacist authoring a comprehensive pharmacognosy textbook and dedicated a big part of his life to improving pharmacotherapy and advancing ethics in the field. Revisiting his contributions provides valuable lessons for contemporary clinical pharmacists

    Fenestrated Physician-Modified Endografts for Preservation of Main and Accessory Renal Arteries in Juxtarenal Aortic Aneurysms.

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    BACKGROUND There is a paucity of reporting outcomes of complex aortic aneurysm treatment such as juxtarenal abdominal aortic aneurysms, where additional techniques to preserve renal artery perfusion are required. METHODS Retrospective analysis of consecutive patients who underwent emergent and elective aortic repair with fenestrated PMEGs between March 2019 and January 2023. Endpoints were technical success, reinterventions, secondary reinterventions and target vessel patency. RESULTS Forty-seven target vessels in 37 patients (23 male, median age 75 years) were targeted, of which 44 were renal arteries (RAs) with a mean diameter of 5.4 ± 1.0 mm. Thirteen were accessory RAs and six had a diameter ≤ 4 mm. Technical success rate was 87% overall; 97% for main and 62% for accessory RAs respectively. Target vessel patency and freedom from secondary reintervention was 100% and 97% at 30 days and 96% and 91% at one year, respectively. There was no 30-day mortality. CONCLUSION Fenestrated physician-modified endografts are safe and effective for the treatment of patients with juxtarenal abdominal aortic aneurysms when incorporating main renal arteries. Limited technical success may be expected when targeting accessory renal arteries, especially when small in diameter. Long-term follow-up is needed to confirm durability of PMEGs for renal artery preservation
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