Mean OD values at 1∶400 serum dilution in patients infected with EBOV during three outbreaks in Gabon, 7 days after symptom onset (Day 7, early humoral response) and 7 or 11 years later (2008, late humoral response), and also in anti-EBOV IgG+ asymptomatic individuals who had never had clinical signs of hemorrhagic fever or who lived in non epidemic areas*.

<p>ODs are color-coded to indicate their intensity (yellow to red). The different colored regions in the proteins indicate the immunodominant domains identified here. *Blank cells indicate that the mean OD was lower than the cut-off. OD: Optical Density. The absorbance cut-off used to identify reactive epitopes is described in the Methodology section.</p

Crystal structure of the trimeric prefusion EBOV GP viewed from the top (above) and side (below) [21].

<p>The three monomers in the complex are colored different shades of grey. Immunodominant regions identified in GP are indicated in color for survivors and asymptomatic patients. The color code matches that of the epitopes identified in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0096360#pone-0096360-g003" target="_blank">Figure 3</a>. Molecular surface of the GP trimer viewed from the side (left) and top (right), as viewed down the three-fold axis. Protein Data Bank file number: 3CSY.</p

Map of Gabonese villages where the 1996 and 2001 outbreaks occurred.

<p>Map of Gabonese villages where the 1996 and 2001 outbreaks occurred.</p

Ollomo_PLoSPathog_2009_PHYML

Maximum likelihood tree inferred from the 4-gene concatenation using PHYML

Ollomo_PLoSPathog_2009

Nucleotide alignment concatenation of 4 mitochondrial genes for 17 Plasmodium species and one outgroup

Total number of <i>Aedes albopictus</i> and <i>Aedes aegypti</i> trapped by location both inside [4]–[9] and outside [1]–[3] the French military camp, Libreville, Gabon, July 2007.

a<p>one pool (21 mosquitoes) infected by CHIKV (July 14^th 2007).</p>b<p>one pool (12 mosquitoes) infected by CHIKV (July 20^th 2007).</p

Additional file 2: of Prevalence of and risk factors for malaria, filariasis, and intestinal parasites as single infections or co-infections in different settlements of Gabon, Central Africa

a) Number of blood samples per site and positive results according to diagnostic methods; b) Number of stool samples per site and positive results according to diagnostic methods. (DOCX 102 kb

Location of mosquito trapping sites both inside [4]–[9] and outside [1]–[3] the military camp of French armed forces in Libreville, Gabon.

<p>Location of mosquito trapping sites both inside <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004691#pone.0004691-Schuffenecker1" target="_blank">[4]</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004691#pone.0004691-Kuniholm1" target="_blank">[9]</a> and outside <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004691#pone.0004691-Ross1" target="_blank">[1]</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004691#pone.0004691-Chretien1" target="_blank">[3]</a> the military camp of French armed forces in Libreville, Gabon.</p

Rainfall in Libreville, Gabon from September 2006 to September 2007 (grey bars) and monthly numbers of suspected Chikungunya cases in Gabon, March 2006–September 2007 (black curve).

<p>Rainfall in Libreville, Gabon from September 2006 to September 2007 (grey bars) and monthly numbers of suspected Chikungunya cases in Gabon, March 2006–September 2007 (black curve).</p

Geographic distribution of Zika and chikungunya and/or dengue viruses infections in Gabon in 2007.

<p>The left-hand panel indicates Gabonese CHIKV and/or DENV cases in green circles and ZIKV cases in purple circles. The right-hand panel shows the location of Libreville suburbs where ZIKV-positive human sera (H) and mosquito pools (M) were detected.</p