mRNA Secondary Structures Fold Sequentially But Exchange Rapidly In Vivo

Self-cleavage assays of RNA folding reveal that mRNA structures fold sequentially in vitro and in vivo, but exchange between adjacent structures is much faster in vivo than it is in vitro

NASA's OCA Mirroring System: An Application of Multiagent Systems in Mission Control

Orbital Communications Adaptor (OCA) Flight Controllers, in NASA's International Space Station Mission Control Center, use different computer systems to uplink, downlink, mirror, archive, and deliver files to and from the International Space Station (ISS) in real time. The OCA Mirroring System (OCAMS) is a multiagent software system (MAS) that is operational in NASA's Mission Control Center. This paper presents OCAMS and its workings in an operational setting where flight controllers rely on the system 24x7. We also discuss the return on investment, based on a simulation baseline, six months of 24x7 operations at NASA Johnson Space Center in Houston, Texas, and a projection of future capabilities. This paper ends with a discussion of the value of MAS and future planned functionality and capabilities