Characteristics and measured exposure of the schools (latest measurement used).

<p>SD: standard deviation.</p><p>GM: geometric mean.</p><p>GSD: geometric standard deviation.</p

Univariate and multivariate analyses of bedroom samples.

<p>GMR: Geometric Mean Ratio.</p><p>95%CI: 95% Confidence Interval.</p><p>In <b>bold</b> are significant univariate associations that are considered in multivariate testing.</p><p><i>Italic</i>: univariate analysis with p<0.20 and considered in multivariate testing.</p><p>NS: variables were included in multivariate testing and found to be not significant.</p><p>Empty: the variable was not included in the specific multivariate model.</p

Study design.

<p>Measurements in schools were performed on 4 different occasions: winter 2009, spring 2009, fall 2009 and winter 2010. Exposure was measured in a total of 215 locations in 19 school buildings. Home measurements were performed all in winter 2010.</p

Univariate and multivariate analyses of classroom measurements.

<p>GMR: Geometric Mean Ratio.</p><p>95%CI: 95% Confidence Interval.</p><p>In <b>bold</b> are significant univariate associations that are considered in multivariate testing.</p><p><i>Italic</i>: univariate analysis with p<0.20 and considered in multivariate testing.</p><p>NS: variables were included in multivariate testing and found to be not significant.</p><p>Empty: the variable was not included in the specific multivariate model.</p

Univariate ORs for a pig farm to be ESBL-<i>E</i>. <i>coli</i>-positive.

<p>Univariate ORs for a pig farm to be ESBL-<i>E</i>. <i>coli</i>-positive.</p

Farm characteristics.

<p>Farm characteristics.</p

Proportions of antimicrobials used over the total DDDA/Y per farm type during the 4 periods (≈6 months) before each sampling moment.

<p>DDDA/Y, defined daily dosages animal per year.</p

Distribution of ESBL genes in isolates from pooled pig samples.

<p>Distribution of ESBL genes in isolates from pooled pig samples.</p

Prevalence of ESBL-<i>E</i>. <i>coli</i>-positive pooled samples from pigs per farm type.

<p>Error bars indicate 95% CIs.</p

Prevalence of ESBL-<i>E</i>. <i>coli</i> in pooled pig samples within different age groups.

<p>Prevalence of ESBL-<i>E</i>. <i>coli</i> in pooled pig samples within different age groups.</p