Survival plots.

<p>a. and b.: Disease-free survival and disease specific survival according to FGFR4 Gly388Arg polymorphism; c. and d.: Disease-free survival and disease specific survival according to FGFR4 expression; e. and f.: Disease-free survival and disease specific survival according to FGFR4 profile.</p

Multivariate analysis of the relationship between clinical and pathological tumor features with gene polymorphism and FGFR4 expression.

a, b<p>Values adjusted by multivariate logistic regression.</p><p>For Gly388Arg and FGFR4 expression correlation with lymphatic embolization and lymph node status, tumor size and differentiation status were considered in the multivariate analysis. For disease relapse and disease specific death, tumor size, lymph node status and radiotherapy treatment were considered.</p

Immunohistochemical analysis of tumors.

<p>(a) strong FGFR4 expression; (b) weak FGFR4 expression. Magnification was 400×.</p

Epidemiological, clinical and pathological tumor features and their association with Gly388Arg polymorphism and FGFR4 expression.

a<p>Not available (not considered in the statistical calculations).</p