50 research outputs found

    Evaluation of antibody response to Plasmodium falciparum in children according to exposure of Anopheles gambiae s.l or Anopheles funestus vectors

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    <p>Abstract</p> <p>Background</p> <p>In sub-Saharan areas, malaria transmission was mainly ensured by <it>Anopheles. gambiae </it>s.l. and <it>Anopheles. funestus </it>vectors. The immune response status to <it>Plasmodium falciparum </it>was evaluated in children living in two villages where malaria transmission was ensured by dissimilar species of <it>Anopheles </it>vectors (<it>An. funestus vs An. gambiae </it>s.l.).</p> <p>Methods</p> <p>A multi-disciplinary study was performed in villages located in Northern Senegal. Two villages were selected: Mboula village where transmission is strictly ensured by <it>An. gambiae </it>s.l. and Gankette Balla village which is exposed to several <it>Anopheles </it>species but where <it>An. funestus </it>is the only infected vector found. In each village, a cohort of 150 children aged from one to nine years was followed during one year and IgG response directed to schizont extract was determined by ELISA.</p> <p>Results</p> <p>Similar results of specific IgG responses according to age and <it>P. falciparum </it>infection were observed in both villages. Specific IgG response increased progressively from one-year to 5-year old children and then stayed high in children from five to nine years old. The children with <it>P. falciparum </it>infection had higher specific antibody responses compared to negative infection children, suggesting a strong relationship between production of specific antibodies and malaria transmission, rather than protective immunity. In contrast, higher variation of antibody levels according to malaria transmission periods were found in Mboula compared to Gankette Balla. In Mboula, the peak of malaria transmission was followed by a considerable increase in antibody levels, whereas low and constant anti-malaria IgG response was observed throughout the year in Gankette Balla.</p> <p>Conclusion</p> <p>This study shows that the development of anti-malaria antibody response was profoundly different according to areas where malaria exposure is dependent with different <it>Anopheles </it>species. These results are discussed according to i) the use of immunological tool for the evaluation of malaria transmission and ii) the influence of <it>Anopheles </it>vectors species on the regulation of antibody responses to <it>P. falciparum</it>.</p

    Lambeau labial total dans les cheiloplasties pour séquelles de noma

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    A generalized finite difference method for the 2-D nonlinear shallow water equations

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    International audienceIn this paper, we propose a generalized finite difference method for two-dimensional non-linear shallow equations. The space discretization uses the staggered grid C of Arakawa. Beside the implicit-explicit factor theta, the time discretization involves a balance ratio alpha of the spatial nodes. The stability analysis takes account the size of the parameters. We discuss the stabilizing properties of the scheme and present some numerical experiments

    A generalized finite difference method for the 2-D nonlinear shallow water equations

    No full text
    International audienceIn this paper, we propose a generalized finite difference method for two-dimensional non-linear shallow equations. The space discretization uses the staggered grid C of Arakawa. Beside the implicit-explicit factor theta, the time discretization involves a balance ratio alpha of the spatial nodes. The stability analysis takes account the size of the parameters. We discuss the stabilizing properties of the scheme and present some numerical experiments

    Sensibilité aux antibiotiques des germes isolés dans les cellulites d'origine dentaire au Sénégal (résultats d'une enquête sur 49 cas).

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    Irregular results sometimes found during antibiotic treatment of perimaxillar cellulitis, conducted the authors to study bacteriology of these infections from dental origin. This study confirmed the aero and anerobic polymicrobism of these cellulitis. Antibiograms realised in 49 cases showed occurrence of streptococcal and anaerobic germs resistance to antibiotics usually prescribed. A nearly constant success of other antibiotics allowed the authors to define a first intention antibiotherapy for the treatment of these infections.English AbstractJournal Articleinfo:eu-repo/semantics/publishe

    Thrombophlébite ptérygo-caverneuse et ankylose temporo-mandibulaire au décours d'une infection dentaire.

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    The authors report the complications of a case of cellulitis from dental origin. A cavernous sinus thrombophlebitis and a temporo-mandibular ankylosis succeed, pointing on the importance of a precocious treatment of dental phlegmons, in order to prevent occurrence of local or regional complications.Case ReportsEnglish AbstractJournal Articleinfo:eu-repo/semantics/publishe

    Arrêt des anticoagulants avant un acte de chirurgie buccale : mythes et réalités

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    Il s’agit d’une étude transversale et descriptive portant sur une période de 9 mois (janvier à septembre 2005). Elle a eu pour cadre le service d’Odontologie d’un centre hospitalier public de la région de Dakar (Sénégal). Elle a concerné 32 patients référés au service d’Odontologie par le Service de Cardiologie. Ils présentaient une pathologie cardio-vasculaire ayant nécessité la prescription d’un anti-vitamine K et ils devaient subir un acte de chirurgie buccale. L’objectif du travail était de déterminer la valeur de l’INR (International Normalized Ratio) permettant de réaliser un acte de chirurgie buccale sans risque hémorragique. Nous avons exploité les paramètres suivants : identification du malade, état bucco-dentaire, type de soins bucco-dentaires, type de cardiopathies, posologie des AVK, valeur de l’INR, moyens d’hémostase. 81,25 % (26 sur 32) des patients étaient des femmes, soit un sexe ratio M/F de 0,23. La moyenne d’âge était de 53 ans, avec des extrêmes de 21 ans et 84 ans. 56,25 % des patients ont subi une seule extraction, 25 % des extractions multiples et 18,75 % ont bénéficié d’un détartrage-curetage. La valeur moyenne de l’INR est de 2,38 avec une variance de 0,07 et un écart type de 0,27. Grâce aux moyens d’hémostase instaurés, aucune complication hémorragique postopératoire n’est survenue. Il semble bien que le risque d’accident thromboembolique à l’arrêt du traitement est beaucoup plus préjudiciable que le risque hémorragique pour le patient. Med Buccale Chir Buccale 2008 ; 14 : 103-109

    Granulome pyogénique palatin chez une femme enceinte

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    Le granulome pyogénique ou botriomycome est une tumeur bénigne vasculaire fréquente sur la muqueuse buccale. Sa localisation palatine est rare. Les variations hormonales liées à la grossesse constituent un facteur favorisant leur développement. Le diagnostic reste anatomopathologique. Nous rapportons un cas de granulome pyogénique chez une femme de 23 ans, enceinte de neuf mois. Elle présentait une tumeur bourgeonnante palatine, pédiculée, s’accompagnant de saignements spontanés. Elle a été excisée au bistouri électrique et aucune récidive n’a été observée après un an
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