Obstructive sleep apnea syndrome in the pediatric age: the role of the dentist

Sleep disordered breathing in children designates a wide spectrum of respiratory disorders characterized by partial or complete obstruction of the upper airways. It ranges from primary snoring, its mildest clinical manifestation, to obstructive sleep apnea syndrome (OSAS): complete obstruction of the upper airways with cessation of airflow. The aim of this paper is to highlight the roles of the pediatric dentist and the orthodontist in the therapeutic approach to pediatric OSAS as a "sentinel" who can detect early signs of the disease for immediate referral to the otolaryngologist and as an active participant in therapy

Energy and economic analysis of a residential Solar Organic Rankine plant

To answer the actual energy, water, economic, social and environmental challenges, renewable, distributed power plants need to be developed. Among renewables, solar tri-generative power plants can be a solution where there is big low temperature heating/cooling demand and small electricity demand, like many residential and industrial utilities. In this case, solar thermal plants can produce thermal energy with low cost and high efficiency. The higher temperature heat not needed by the user can be exploited via Organic Rankine Cycle to produce electrical energy and desalinized water via reverse osmosis. The present paper analyses, via TRNSYS simulation, a system composed of 50 m2 of CPC solar thermal collectors, 3 m3 of thermal storage, a synthetic heat transfer fluid, 3 kWe ORC, 8 kWth absorber, 200 l/h direct reverse osmosis desalination device. The system is able to produce power, heating/cooling and fresh water needs for a residential house. Although system’s components are well known technologies, the integration to a efficient and economic working system is still a challenge. Global energy and economic analyses have been performed. Low temperature heating/cooling terminals allow to increase not only the use of thermal energy but also the ORCand absorber efficiency. ORC-Absorber configuration and relative fluids and temperatures are central. Government support and/or cost reduction of 30% are necessary to have positive NPV and acceptable PBT and IR

Phase structure of a generalized Nambu Jona-Lasinio model with Wilson fermions in the mean field or large NN-expansion

We analyze the vacuum structure of a generalized lattice Nambu--Jona-Lasinio model with two flavors of Wilson fermions, such that its continuum action is the most general four-fermion action with 'trivial' color interactions, and having a $SU(2)_V x SU(2)_A$ symmetry in the chiral limit. The phase structure of this model in the space of the two four-fermion couplings shows, in addition to the standard Aoki phases, new phases with $!= 0$, in close analogy to similar results recently suggested by some of us for lattice QCD with two degenerate Wilson fermions. This result shows how the phase structure of an effective model for low energy QCD cannot be entirely understood from Wilson Chiral Perturbation Theory, based on the standard QCD chiral effective Lagrangian approach.Comment: 24 pages, 3 figures, sent to Nuclear Physics

Towards Drift Correction in Chemical Sensors Using an Evolutionary Strategy

Gas chemical sensors are strongly affected by the so-called drift, i.e., changes in sensors' response caused by poisoning and aging that may significantly spoil the measures gathered. The paper presents a mechanism able to correct drift, that is: delivering a correct unbiased fingerprint to the end user. The proposed system exploits a state-of-the-art evolutionary strategy to iteratively tweak the coefficients of a linear transformation. The system operates continuously. The optimal correction strategy is learnt without a-priori models or other hypothesis on the behavior of physical-chemical sensors. Experimental results demonstrate the efficacy of the approach on a real problem

Direct-acting antivirals and visceral leishmaniasis: A case report

Background: Visceral leishmaniasis is a vector-borne parasitic disease caused by protozoa belonging to the genus Leishmania. The clinical presentation of visceral leishmaniasis strictly depends on the host immunocompetency, whereas depressive conditions of the immune system impair the capability to resolve the infection and allow reactivation from sites of latency of the parasite. Case presentation: We describe a case of visceral leishmaniasis (VL) that occurred in a patient with chronic hepatitis C treated with direct-acting antiviral drugs (DAA). The hypothesized mechanism is the alteration of protective inflammation mechanisms secondary to DAA therapy. Downregulation of type II and III IFNs, their receptors, which accompany HCV clearance achieved during treatment with sofosbuvir and ribavirin might have a negative impact on a risk for reactivation of a previous Leishmania infection. We know indeed that IFN-\u3b3 is important to enhance killing mechanisms in macrophages, which are the primary target cells of Leishmania. Conclusion: Since VL is endemic in Sicily as well as in other countries of the Mediterranean basin, physicians should be aware of the possible unmasking of cryptic Leishmania infection by DAAs

Experimental tests to recover the photovoltaic power by battery system

The uncertainty and variability of the Renewable Energy Sources (RES) power plants within the power grid is an open issue. The present study focuses on the use of batteries to overcome the limitations associated with the photovoltaic inverter operation, trying to maximize the global energy produced. A set of switches, was placed between a few photovoltaic modules and a commercial inverter, capable to change configuration of the plant dynamically. Such system stores the power that the inverter is not able to let into the grid inside batteries. At the base of this optimization, there is the achievement of two main configurations in which the batteries and the photovoltaic modules are electrically connected in an appropriate manner as a function of inverter efficiency and thus solar radiation. A control board and the relative program, to change the configuration, was designed and implemented, based on the value of the measured radiation, current, batteries voltage, and calculated inverter efficiency. Finally from the cost and impact analysis we can say that, today the technology of lithium batteries, for this application, is still too expensive in comparison with lead-acid batteries

NonClassicality Criteria in Multiport Interferometry

Interference lies at the heart of the behavior of classical and quantum light. It is thus crucial to understand the boundaries between which interference patterns can be explained by a classical electromagnetic description of light and which, on the other hand, can only be understood with a proper quantum mechanical approach. While the case of two-mode interference has received a lot of attention, the multimode case has not yet been fully explored. Here we study a general scenario of intensity interferometry: we derive a bound on the average correlations between pairs of output intensities for the classical wavelike model of light, and we show how it can be violated in a quantum framework. As a consequence, this violation acts as a nonclassicality witness, able to detect the presence of sources with sub-Poissonian photon-number statistics. We also develop a criterion that can certify the impossibility of dividing a given interferometer into two independent subblocks.Comment: 5 + 3 pages, published versio

Efficient and stable perovskite large area cells by low-cost fluorene-xantene-based hole transporting layer

Among the new generation photovoltaics, perovskite solar cell (PSC) technology reached top efficiencies in a few years. Currently, the main objective to further develop PSCs is related to the fabrication of stable devices with cost-effective materials and reliable fabrication processes to achieve a possible industrialization pathway. In the n-i-p device configuration, the hole transporting material (HTM) used most is the highly doped organic spiro-fluorene-based material (Spiro-OMeTAD). In addition to the high cost related to its complex synthesis, this material has different issues such as poor photo, thermal and moisture stability. Here, we test on small and large area PSCs a commercially available HTM (X55, Dyenamo) with a new core made by low-cost fluorene-xantene units. The one-pot synthesis of this compound reduces 30 times its cost with respect to Spiro-OMeTAD. The optoelectronic performances and properties are characterized through JV measurement, IPCE (incident photon to current efficiency), steady-state photoluminescence and ISOS stability test. SEM (scanning electron microscope) images reveal a uniform and pinhole free coverage of the X55 HTM surface, which reduces the charge recombination losses and improves the device performance relative to Spiro-OMeTAD from 16% to 17%. The ISOS-D-1 stability test on large area cells without any encapsulation reports an efficiency drop of about 15% after 1000 h compared to 30% for the reference case