25 research outputs found
Convenient Synthesis of (3R, 4S)-4-Methyl-3-hexanol and (S)-4-Methyl-3-hexanone, the Pheromones of Ants
Synthesis of enantiopure pheromones I and II, both of them bearing chiral methyl branching and an α-oxygenated carbon centre, has been accomplished using compound 2 prepared from D-mannitol as the chiral precursor
Convenient Synthesis of (3R, 4S)-4-Methyl-3-hexanol and (S)-4-Methyl-3-hexanone, the Pheromones of Ants
Synthesis of enantiopure pheromones I and II, both of them bearing chiral methyl branching and an α-oxygenated carbon centre, has been accomplished using compound 2 prepared from D-mannitol as the chiral precursor
Catalytic Oxidation of 3‑Arylbenzofuran-2(3<i>H</i>)‑ones with PCC‑H<sub>5</sub>IO<sub>6</sub>: Syntheses of 3‑Aryl-3-hydroxy/3-amido-3-arylbenzofuran-2(3<i>H</i>)‑ones
A pyridinium chlorochromate (PCC)-mediated
facile oxidative dimerization of 3-arylbenzofuran-2-ones at ambient
temperature was developed which undergo oxidative cleavage to 3-aryl-3-hydroxy-benzofuran-2-ones
with PCC at elevated temperatures. Finally, direct oxidation of 3-arylbenzofuran-2-ones
to 3-aryl-3-hydroxy-benzofuran-2-ones was realized using a combination
of PCC (10 mol %) and 2.0 equiv of H<sub>5</sub>IO<sub>6</sub>. The
synthesized 3-aryl-3-hydroxy-benzofuranones were further converted
to corresponding 3-amido-3-aryl-benzofuranones in high yields by Ritter
reaction. Thus, the present protocol provides a nonconventional approach
to C-3 hydroxylation of 3-arylbenzofuranones via their dimer using
a catalytic amount of inexpensive chromiumÂ(VI) oxidant
Catalytic Oxidation of 3‑Arylbenzofuran-2(3<i>H</i>)‑ones with PCC‑H<sub>5</sub>IO<sub>6</sub>: Syntheses of 3‑Aryl-3-hydroxy/3-amido-3-arylbenzofuran-2(3<i>H</i>)‑ones
A pyridinium chlorochromate (PCC)-mediated
facile oxidative dimerization of 3-arylbenzofuran-2-ones at ambient
temperature was developed which undergo oxidative cleavage to 3-aryl-3-hydroxy-benzofuran-2-ones
with PCC at elevated temperatures. Finally, direct oxidation of 3-arylbenzofuran-2-ones
to 3-aryl-3-hydroxy-benzofuran-2-ones was realized using a combination
of PCC (10 mol %) and 2.0 equiv of H<sub>5</sub>IO<sub>6</sub>. The
synthesized 3-aryl-3-hydroxy-benzofuranones were further converted
to corresponding 3-amido-3-aryl-benzofuranones in high yields by Ritter
reaction. Thus, the present protocol provides a nonconventional approach
to C-3 hydroxylation of 3-arylbenzofuranones via their dimer using
a catalytic amount of inexpensive chromiumÂ(VI) oxidant
Catalytic Oxidation of 3‑Arylbenzofuran-2(3<i>H</i>)‑ones with PCC‑H<sub>5</sub>IO<sub>6</sub>: Syntheses of 3‑Aryl-3-hydroxy/3-amido-3-arylbenzofuran-2(3<i>H</i>)‑ones
A pyridinium chlorochromate (PCC)-mediated
facile oxidative dimerization of 3-arylbenzofuran-2-ones at ambient
temperature was developed which undergo oxidative cleavage to 3-aryl-3-hydroxy-benzofuran-2-ones
with PCC at elevated temperatures. Finally, direct oxidation of 3-arylbenzofuran-2-ones
to 3-aryl-3-hydroxy-benzofuran-2-ones was realized using a combination
of PCC (10 mol %) and 2.0 equiv of H<sub>5</sub>IO<sub>6</sub>. The
synthesized 3-aryl-3-hydroxy-benzofuranones were further converted
to corresponding 3-amido-3-aryl-benzofuranones in high yields by Ritter
reaction. Thus, the present protocol provides a nonconventional approach
to C-3 hydroxylation of 3-arylbenzofuranones via their dimer using
a catalytic amount of inexpensive chromiumÂ(VI) oxidant
Catalytic Oxidation of 3‑Arylbenzofuran-2(3<i>H</i>)‑ones with PCC‑H<sub>5</sub>IO<sub>6</sub>: Syntheses of 3‑Aryl-3-hydroxy/3-amido-3-arylbenzofuran-2(3<i>H</i>)‑ones
A pyridinium chlorochromate (PCC)-mediated
facile oxidative dimerization of 3-arylbenzofuran-2-ones at ambient
temperature was developed which undergo oxidative cleavage to 3-aryl-3-hydroxy-benzofuran-2-ones
with PCC at elevated temperatures. Finally, direct oxidation of 3-arylbenzofuran-2-ones
to 3-aryl-3-hydroxy-benzofuran-2-ones was realized using a combination
of PCC (10 mol %) and 2.0 equiv of H<sub>5</sub>IO<sub>6</sub>. The
synthesized 3-aryl-3-hydroxy-benzofuranones were further converted
to corresponding 3-amido-3-aryl-benzofuranones in high yields by Ritter
reaction. Thus, the present protocol provides a nonconventional approach
to C-3 hydroxylation of 3-arylbenzofuranones via their dimer using
a catalytic amount of inexpensive chromiumÂ(VI) oxidant