Carbepenam resistance prevalence in north India: A retrospective analysis

Background: We investigated the clinical consequences of healthcare-associated bacteremia in light of rising antimicrobial resistance and limited therapy choices for carbapenem-resistant bacteremia. Methods: Between March 2020 and March 2022, a retrospective observational study of carbapenem-resistant Gram-negative bacteremia was conducted at a tertiary care hospital in North India. Results: Patients in our study spent an average of 11.76 days in the intensive care unit (ICU), with a mean time to bacteremia of 6.4 days following admission. Klebsiella pneumoniae was the most prevalent pathogen (44 percent). Patients receiving combination treatment had a reduced death rate (44.8%) than those receiving colistin monotherapy (66.6%) (P = 0.35). Conclusion: Carbapenem resistant bacteremia is a late-onset illness that affects patients who have been exposed to antibiotics in the ICU and has a 60 percent mortality rate after 30 days

Comparative study of sevoflurane versus propofol for laryngeal mask airway insertion in adults

Background: Propofol is a preferred induction agent for laryngeal mask airway (LMA) insertion due to its propensity of suppressing oropharyngeal and cough reflexes. Sevoflurane is a nonpungent inhalation anesthetic agent which can be used as an induction agent. The aim of the present study was to compare Sevoflurane versus Propofol for laryngeal mask airway insertion in adults. Material and methods: The present study was carried out in 300 patients to compare Sevoflurane versus Propofol for laryngeal mask airway insertion in adults. In Group-A: induction with propofol and in Group-B: induction was done with inhalational sevoflurane 8. Various vital parameters and other clinical parameters were recorded and compared in both the groups. The statistical analysis was done. Results:Propofol  needed leser time to loss of eyelash reflex, Time to jaw relaxation, Time to completion of successful insertion of Laryngeal Mask Airway. The percentage of patients who had successful LMA insertion at first attempt was larger with propofol. The duration of apnea was longer in group propofol. Excitatory movement was more in group propofol. Cough, laryngospasm was absent in propofol. Hiccups was absent in both groups. During insertion of LMA, coughing, gagging was absent in group sevoflurane and laryngospasm was absent in propofol.&nbsp

Carbepenam Resistance Prevalence in North India: A Retrospective Analysis

Background: We investigated the clinical consequences of healthcare-associated bacteremia in light of rising antimicrobial resistance and limited therapy choices for carbapenem-resistant bacteremia. Methods: Between March 2020 and March 2022, a retrospective observational study of carbapenem-resistant Gram-negative bacteremia was conducted at a tertiary care hospital in North India. Results: Patients in our study spent an average of 11.76 days in the intensive care unit (ICU), with a mean time to bacteremia of 6.4 days following admission. Klebsiella pneumoniae was the most prevalent pathogen (44 percent). Patients receiving combination treatment had a reduced death rate (44.8%) than those receiving colistin monotherapy (66.6%) (P = 0.35). Conclusion: Carbapenem resistant bacteremia is a late-onset illness that affects patients who have been exposed to antibiotics in the ICU and has a 60 percent mortality rate after 30 days