Productivity and Profitability Assessment of Drought Tolerant Rice Cultivars under Different Crop Management Practices in Central Terai of Nepal

Reduction in productivity has led to lower profitability of rice production in Nepal. Proper selections of resource conservation technologies and drought tolerant cultivars are being potential strategies determining productivity of rice in drought prone areas. Thus, a field experiment was accomplished in central-terai of Nepal during 2014 to assess the productivity and profitability of drought tolerant rice cultivars under different crop management practices. The experiment was carried out in strip-plot design with three replications consisting four drought tolerant rice cultivars and three crop management practices. The analyzed data revealed that SRI (System of Rice Intensification) produced significantly higher grain yield (5.28 t ha-1) than other management practices. The straw yield of SRI (5.12 t ha-1) was also significantly higher than other management practices. The cultivars had no influence on grain yield, but the straw yield was significantly influenced by cultivars, with the highest straw yield in Sukkha-3 (5.21 t ha-1). Similarly, SRI management practice also had significantly higher gross returns (NRs. 144652 ha-1), net return (NRs. 56647 ha-1) and B:C ratio (1.64:1). Thus, SRI management practice can be adopted as adaptation approach for obtaining higher productivity and profitability in central terai and similar agro-climatic regions of Nepal

Assessment of Yield and Yield Attributing Characters of Hybrid Maize using Nutrient Expert® Maize Model in Eastern Terai of Nepal

Indiscriminate use of fertilizer and lack of site specific nutrient management technology is the main cause of low maize productivity in Nepal. Thus, field experiments on farmer\u27s field were conducted on maize to assess the productivity at two sites of Jhapa district viz. Damak and Gauradaha using Nutrient Expert® Maize model from November 2015 to May 2016. The experiment was laid out in Randomized Completely Block Design consisting two treatments viz. NE (Nutrient Expert recommendation) and FFP (Farmer\u27s Fertilizer Practice) with twenty replications. The result revealed significant differences in terms of grain yield, stover yield, biological yield, and yield attributing characters. NE based practices produced higher grain yield (9.22 t ha-1), which was 86.6 percent higher than FFP (4.94 t ha-1). Similarly, higher average cob number m 2 (8.2), average kernel rows cob-1 (14.2), average kernels number row-1 (589.9) and test weight (361.4 g) were recorded in NE based practice. Thus, NE based practice can be adopted for obtaining higher productivity in eastern terai region of Nepal

Direct oral anticoagulants (DOAC) versus vitamin K antagonist in left ventricular thrombus: An updated meta‐analysis

Abstract Background and Aims Current clinical guidelines for treating left ventricular thrombus (LVT) are limited by inadequate evidence to inform the comparative efficacy of oral anticoagulants. In this meta‐analysis, we aimed to compare the efficacy and safety of direct oral anticoagulants (DOAC) to vitamin K antagonists (VKA) in patients with LVT. Methods Four standard databases were searched for relevant literature comparing the efficacy and safety between DOAC and VKA for LVT treatment, published before August 19, 2023. Both the randomized controlled trials and observational studies were included in the analysis. The outcomes of interest were the resolution of LVT, all‐cause mortality, stroke, systemic embolism, and bleeding. Data from the selected studies were extracted and analyzed using RevMan 5.4 using odds ratio. Results Among 3959 studies from the database search and bibliography review, 33 were included in the analysis. LVT resolution was observed in 72.59% in the DOAC group versus 67.49% in the VKA group (odds ratio [OR]: 1.28, confidence interval [CI]: 1.07–1.53). Mortality was lower in the DOAC group (11.71% vs. 18.56%) (OR: 0.60, CI: 0.36–1.00; borderline statistical significance). Likewise, bleeding events (9.60% vs. 13.19%) (OR: 0.65, CI: 0.52–0.81) and stroke (7.54% vs. 11.04%) (OR: 0.71, CI: 0.53–0.96) were also significantly lower in the DOAC group. Conclusion DOAC use for LVT showed better thrombus resolution and reduced risk of bleeding and stroke compared to VKA. Likewise, DOAC use was associated with lower mortality with borderline statistical significance