Potensi Ekstrak Daun Kelor (Moringa Oleifera) sebagai Hepatoprotektor pada Tikus Putih (Rattus novergicus) yang Diinduksi Parasetamol Dosis toksik

Moringa Oleifera is a plant that contains chemical compounds that are useful, such as flavonoids. The ability of this flavonoid compound that can capture free radicals cause damage and hepatoprotektan hepar. Purpose of study was to determined levels of Moringa leaf extract which can overcome the effects of liver damage caused by toxic doses of paracetamol through MDA, SGOT and SGPT Method used in this laboratory experimental study is a Randomized Post Test Only Control Group Design with the following stages: 1. Moringa Leaf Extraction with Ethanol 96%; Try 2.Preparasi animals, 3. Treatment of Animals Try the extract of leaves of Moringa 3 dose is: 250mg / 200BB rat (dose of A), 500mg / 200BB mice (dose B), 1000mg / 200BB mice (dose C) for 14 days in combination with paracetamol 2 g / 200BB mice, compared to the negative control group (group given just paracetamol 2 g / 200BB rat) and the positive control group (the group who were given regular feed) for 14 days.Results : turned out to be no difference in the reduction in SGOT levels are statistically significant between the negative control group with high-dose treatment group ie the dose C with =0,016 smaller than 0.05, whereas a decrease in ALT levels were significantly decreased in the treatment group high dose is the dose C with =0,009 smaller than 0.05. While MDA group treated with the negative control group experienced an overall decline for the dose A with =0,05, dose B with =0,0011 and dose C with =0,001. Conclusion of this study showed that the extract of Moringa leaves can be potentially as an antioxidant in all doses at once can be as hepatoprotektor at high doses is 1000mg / 200BB Rattus Novergicus

POTENTIAL EXTRACT OF Moringa Oleifera AS HEPATOPROTECTIVE IN WHITE RATS (Rattus novergicus) INDUCED TOXIC DOSES OF PARACETAMOL

Moringa Oleifera is a plant that contains chemical compounds that are useful, such as flavonoids. The ability of this flavonoid compound that can capture free radicals cause damage and hepatoprotektan hepar. Purpose of study was to determined levels of Moringa leaf extract which can overcome the effects of liver damage caused by toxic doses of paracetamol through MDA, SGOT and SGPT Method used in this laboratory experimental study is a Randomized Post Test Only Control Group Design with the following stages: 1. Moringa Leaf Extraction with Ethanol 96%; Try 2.Preparasi animals, 3. Treatment of Animals Try the extract of leaves of Moringa 3 dose is: 250mg / 200BB rat (dose of A), 500mg / 200BB mice (dose B), 1000mg / 200BB mice (dose C) for 14 days in combination with paracetamol 2 g / 200BB mice, compared to the negative control group (group given just paracetamol 2 g / 200BB rat) and the positive control group (the group who were given regular feed) for 14 days. Results : turned out to be no difference in the reduction in SGOT levels are statistically significant between the negative control group with high-dose treatment group ie the dose C with =0,016 smaller than 0.05, whereas a decrease in ALT levels were significantly decreased in the treatment group high dose is the dose C with =0,009 smaller than 0.05. While MDA group treated with the negative control group experienced an overall decline for the dose A with =0,05, dose B with =0,0011 and dose C with =0,001. Conclusion of this study showed that the extract of Moringa leaves can be potentially as an antioxidant in all doses at once can be as hepatoprotektor at high doses is 1000mg / 200BB Rattus Novergicus

Prospects for neutrino astrophysics with Hyper-Kamiokande

Hyper-Kamiokande is a multi-purpose next generation neutrino experiment. The detector is a two-layered cylindrical shape ultra-pure water tank, with its height of 64 m and diameter of 71 m. The inner detector will be surrounded by tens of thousands of twenty-inch photosensors and multi-PMT modules to detect water Cherenkov radiation due to the charged particles and provide our fiducial volume of 188 kt. This detection technique is established by Kamiokande and Super-Kamiokande. As the successor of these experiments, Hyper-K will be located deep underground, 600 m below Mt. Tochibora at Kamioka in Japan to reduce cosmic-ray backgrounds. Besides our physics program with accelerator neutrino, atmospheric neutrino and proton decay, neutrino astrophysics is an important research topic for Hyper-K. With its fruitful physics research programs, Hyper-K will play a critical role in the next neutrino physics frontier. It will also provide important information via astrophysical neutrino measurements, i.e., solar neutrino, supernova burst neutrinos and supernova relic neutrino. Here, we will discuss the physics potential of Hyper-K neutrino astrophysics

Construction status and prospects of the Hyper-Kamiokande project

The Hyper-Kamiokande project is a 258-kton Water Cherenkov together with a 1.3-MW high-intensity neutrino beam from the Japan Proton Accelerator Research Complex (J-PARC). The inner detector with 186-kton fiducial volume is viewed by 20-inch photomultiplier tubes (PMTs) and multi-PMT modules, and thereby provides state-of-the-art of Cherenkov ring reconstruction with thresholds in the range of few MeVs. The project is expected to lead to precision neutrino oscillation studies, especially neutrino CP violation, nucleon decay searches, and low energy neutrino astronomy. In 2020, the project was officially approved and construction of the far detector was started at Kamioka. In 2021, the excavation of the access tunnel and initial mass production of the newly developed 20-inch PMTs was also started. In this paper, we present a basic overview of the project and the latest updates on the construction status of the project, which is expected to commence operation in 2027

A dynamical comparison between two recent drought southwest monsoon seasons 2002 and 2009 over India

An attempt has been made to compare dynamically the recent two drought years,viz., 2002 and 2009, from energetics aspects. For that different energy terms, their generation and conversion among different terms have been computed during 1st May - 30th September for the above two years over a limited region between 65° E & 95° E, 5° N & 35° N. These computations are based on daily NCEP 2.5° × 2.5° data during 1st May - 30th September of the above two years

Potensi Ekstrak Daun Kelor (Moringa Oleifera) sebagai Hepatoprotektor pada Tikus Putih (Rattus novergicus) yang Diinduksi Parasetamol Dosis toksik

Moringa Oleifera is a plant that contains chemical compounds that are useful, such as flavonoids. The ability of this flavonoid compound that can capture free radicals cause damage and hepatoprotektan hepar. Purpose of study was to determined levels of Moringa leaf extract which can overcome the effects of liver damage caused by toxic doses of paracetamol through MDA, SGOT and SGPT Method used in this laboratory experimental study is a Randomized Post Test Only Control Group Design with the following stages: 1. Moringa Leaf Extraction with Ethanol 96%; Try 2.Preparasi animals, 3. Treatment of Animals Try the extract of leaves of Moringa 3 dose is: 250mg / 200BB rat (dose of A), 500mg / 200BB mice (dose B), 1000mg / 200BB mice (dose C) for 14 days in combination with paracetamol 2 g / 200BB mice, compared to the negative control group (group given just paracetamol 2 g / 200BB rat) and the positive control group (the group who were given regular feed) for 14 days.Results : turned out to be no difference in the reduction in SGOT levels are statistically significant between the negative control group with high-dose treatment group ie the dose C with =0,016 smaller than 0.05, whereas a decrease in ALT levels were significantly decreased in the treatment group high dose is the dose C with =0,009 smaller than 0.05. While MDA group treated with the negative control group experienced an overall decline for the dose A with =0,05, dose B with =0,0011 and dose C with =0,001. Conclusion of this study showed that the extract of Moringa leaves can be potentially as an antioxidant in all doses at once can be as hepatoprotektor at high doses is 1000mg / 200BB Rattus Novergicus.</jats:p

​Efficacy of Bioagents against Sclerotinia Rot of Chickpea Incited by Sclerotinia sclerotiorum

Background: Sclerotinia sclerotiorum (Lib.) de Barry is a soil-borne plant pathogen, capable of infecting more than 500 host plants worldwide. It is a major pathogen that plays a crucial role in reducing the yield of economically important crops. Sclerotinia rot also known as Stem rot or white mold, caused by Sclerotinia sclerotiorum is a serious disease of chickpea. Methods: The antagonistic potential of four bioagents i.e. Trichoderma harzianum (Th-BKN), Trichoderma viride (Tv-BKN), Pseudomonas fluorescens (Pf-BKN) and Bacillus subtilis (Bs- BKN) were isolated from chickpea rhizospheric soil. The fungal bioagents were tested for their antagonistic potential against the pathogen in vitro by modified dual culture technique on potato dextrose agar (PDA) medium. While bacterial antagonists tested for their antagonistic potential against the pathogen in vitro by paper disc inoculation technique on Nutrient Agar (NA) and Pseudomonas Agar Fluorescens (PAF) media. Each treatment was replicated four times, incubated at 23±10°C, data on the antagonistic activity of different bioagents were recorded and percent inhibition was calculated for each antagonist. Result: The fungal antagonists T. harzianum (Th-BKN) resulted in maximum growth inhibition of the pathogen (70.48%) and bacterial antagonists, Pseudomonas fluorescens (Pf-BKN) (37.56%) was more effective than the Bacillus subtilis (Bs- BKN). </jats:p

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Not AvailableThe organic carbon and soils of the world comprise bulk of the terrestrial carbon and serve as a major sink and source of atmospheric carbon. Increasing atmospheric concentrations of green house gases may be mitigated by increasing carbon sequestration in vegetation and soil. The study attempted to estimate biomass production and carbon sequestration potential of different plantation ecosystems in north western Himalaya, India. Biomass, carbon density of biomass, soil, detritus, carbon sequestration and CO2 mitigation potential were studied under different plantation forest ecosystems comprising of eight different tree species: Quercus leucotrichophora, Pinus roxburghii, Acacia catechu, Acacia mollissima, Albizia procera, Alnus nitida, Eucalyptus tereticornis and Ulmus villosa. Above (185.57±48.99 tha-1) and below ground (42.47±10.38 tha-1) biomass was maximum in Ulmus villosa. The vegetation carbon density was maxium in Albizia procera (118.37±1.49 tha-1) and minimum (36.50±9.87 tha-1) in Acacia catechu. Soil carbon density was maximum (219.86±10.34 tha-1) in Alnus nitida, and minimum (170.83±20.60 tha-1) in Pinus roxburghii. Detritus was higher in Pinus roxburghii (6.79±2.0 tha-1). Carbon sequestration (7.91±3.4 tha-1) and CO2 mitigation potential (29.09±12.78 tha-1) was maximum in Ulmus villosa. Pearson correlation matrix revealed significant positive relationship of ecosystem carbon with plantation biomass, soil carbon and CO2 mitigation potential. With the emerging threat of climate change, such assessment of forest and soil carbon inventory would allow to devise best land management and policy decisions for sustainable management of fragile hilly ecosystem.Not Availabl