On hydromagnetic flow due to a rotating disk with radiation effects

The effect of thermal radiation on the steady laminar convective hydromagnetic flow of a viscous and electrically conducting fluid due to a rotating disk of infinite extend is studied. The fluid is subjected to an external uniform magnetic field perpendicular to the plane of the disk. The governing Navier–Stokes and Maxwell equations of the hydromagnetic fluid, together with the energy equation, are transformed into nonlinear ordinary differential equations by using the von Karman similarity transformations. The resulting nonlinear ordinary differential equations are then solved numerically subject to the transformed boundary conditions by Runge–Kutta based shooting method. Comparisons with previously published works are performed and the results are found to be in excellent agreement. Numerical and graphical results for the velocity and temperature profiles as well as the skin friction and Nusselt number are presented and discussed for various parametric conditions

Effects of Thermal Radiation on Hydromagnetic Flow due to a Porous Rotating Disk with Hall Effect

Radiation effect on steady laminar hydromagnetic flow of a viscous, Newtonian and electrically conducting fluid past a porous rotating infinite disk is studied taking Hall current into account. The system of axisymmetric nonlinear partial differential equations governing the MHD flow and heat transfer are reduced to nonlinear ordinary differential equations by introducing suitable similarity variables introduced by von Karman and the resulting nonlinear equations are solved numerically using Runge-Kutta based shooting method. A parametric study of all parameters involved was conducted and a representative set of results showing the effect of the magnetic field, the radiation parameter, the uniform suction/injection parameter and Hall parameter are illustrated graphically. The numerical values of the radial and tangential skin-friction coefficient and Nusselt number are calculated and displayed in the tables showing the effects of various parameters. Finally, a good comparison between the present numerical predictions and the previously published data are presented in the absence of magnetic field and radiation

Qualitative and quantitative analysis of antibody response in childhood tuberculosis against antigens of Mycobacterium tuberculosis

Purpose: Serodiagnosis of tuberculosis in children, using available crude antigens, has been difficult. The tests lack sufficient sensitivity and/or specificity. In this study, western blot analysis of M. tuberculosis H37Rv culture filtrate antigen (CFA) was carried out, to identify diagnostically useful antigens. In addition, the CFA was also used in enzyme linked immunosorbent assay (ELISA), to measure antibodies of multiple isotypes. Methods: Specific IgG, IgA and IgM antibodies were estimated in the sera from 26 clinically/ bacteriologically diagnosed cases of childhood tuberculosis (CTB) and 61 normal children (CNHS), using culture filtrate antigen. Western blot analysis with culture filtrate antigen was carried out to qualitatively compare the antibody profile among the CTB, with childhood normal controls and adult TB. Results: IgG positivity was only 7.6% with culture filtrate antigen in the CTB group, while 3.2% among the controls were also positive. However, the results of IgA and IgM isotypes were better. By combination of all the three isotypes an increased sensitivity of 57.7% with a specificity of 93.5%, was obtained. Immunoblot analysis revealed marked difference among antibodies in the region of 16, 19, 38 and 45kDa between CTB and CNHS. Conclusions: Our findings point to a limited sensitivity of 57.7% in ELISA with culture filtrate antigen. However, antibodies around 16, 19,38 and 45kDa region may be useful in differentiating the CTB patients from CNHS by immunoblot assay

Local Invariants and Pairwise Entanglement in Symmetric Multi-qubit System

Pairwise entanglement properties of a symmetric multi-qubit system are analyzed through a complete set of two-qubit local invariants. Collective features of entanglement, such as spin squeezing, are expressed in terms of invariants and a classifcation scheme for pairwise entanglement is proposed. The invariant criteria given here are shown to be related to the recently proposed (Phys. Rev. Lett. 95, 120502 (2005)) generalized spin squeezing inequalities for pairwise entanglement in symmetric multi-qubit states.Comment: 9 pages, 2 figures, REVTEX, Replaced with a published versio

Isolation and Evaluation of Diagnostic Value of Two Major Secreted Proteins of Mycobacterium Tuberculosis

Two secreted antigens of Mycobacterium tuberculosis, namely the antigen 85 complex (30/31) and 38kDa antigens, were purified from the whole culture filtrate by using two dimensional preparative electrophoresis and anion exchange chromatography, respectively. Individual components of the antigen 85 complex namely, antigen 85A, 85B and 85C, were separated using hydrophobic interaction chromatography. The humoral antibody activity to these antigens in sputum positive cases of active pulmonary tuberculosis and normal healthy volunteers was determined by enzyme linked immunosorbent assay (ELISA) and immunoblot. Recombinant 38kDa and antigen 6 were used as reference antigens for the assay. None of the healthy volunteers reacted with the 38kDa antigen, while 52% of the TB sera reacted with it. Of the three components of the antigen 85 complex, 85B gave the highest positivity of 40 per cent. The results of combination of 38kDa with antigen 6 offered better results with 76% positivity

Production & characterization of monoclonal antibodies to Mycobacterium tuberculosis

Background & objectives: Monoclonal antibodies (MAbs) against Mycobacterium tuberculosis H37Rv culture filtrate (CF) were raised by immunizing BALB/c mice and characterization was done. Attempts have been directed towards identifying mycobacterial antigens in biological fluids by employing polyclonal and monoclonal antibodies specific for M. tuberculosis. Immunohistologic studies, using MAbs for the localization of whole or fragmented bacilli in the biopsy specimens were also carried out. Methods: Intrasplenic IS and intraperitoneal IP routes of immunization, were compared. The MAbs were characterized for their isotype, binding specificity, nature of binding epitope, reactivity in immunoassays etc. Results: IS and IF’ routes of immunization, were compared and IP was found superior. Ten MAbs designated TRC l-10 were produced. Of these, 7 MAbs, TRC 1-7 reacted with the 30/31 kDa doublet (antigen 85 complex), TRC 8 with 12 kDa in addition to 30/31 kDa and TRC 9 and 10 with the 24 and 12 kDa antigens respectively. Six MAbs were classified as broadly cross reactive and 2 showed limited cross reactivity. TRC 8 and 10 showed species specificity. Employing TRC 8 in sandwich ELISA, antigen was detected in sera from 17 of 25 pulmonary tuberculosis patients and 3 of 20 controls. TRC 8 was found to be useful in detecting antigens specifically in M. tuberculosis and M. leprae infected tissues, by immunoperoxidase staining. Interpretation & conclusion: TRC 8 was found to be restricted in its reactivity to M. tuberculosis complex and M, leprae. TRC 8 may prove useful in immuno-diagnosis of tuberculosis

Constraints on the uncertainties of entangled symmetric qubits

We derive necessary and sufficient inseparability conditions imposed on the variance matrix of symmetric qubits. These constraints are identified by examining a structural parallelism between continuous variable states and two qubit states. Pairwise entangled symmetric multiqubit states are shown here to obey these constraints. We also bring out an elegant local invariant structure exhibited by our constraints.Comment: 5 pages, REVTEX, Improved presentation; Theorem on neccessary and sufficient condition included; To appear in Phys. Lett.

HLA-DR phenotypes and IgG, IgA and IgM antibody responses to Mycobacterium tuberculosis culture filtrate and 30 kDa antigens in pulmonary tuberculosis

The role of HLA-DR genetic make-up on the IgG, IgA and IgM antibody response to Mycobacterium tuberculosis culture filtrate and 30 kDa antigens was studied in pulmonary tuberculosis. The study was carried out in HLA-DR typed active pulmonary tuberculosis (ATB) patients (n = 37), inactive (cured) pulmonary tuberculosis (ITB) patients (n = 79) and normal healthy subjects (NHS; n = 46). In ATB and ITB (cured) patients, IgG antibody (optical density at 490 nm for 1 : 3200 dilution) as measured by enzyme-linked immunosorbent assay was the predominant one than IgA and IgM antibodies. Increased IgG antibody titre to culture filtrate (P = 0.03) and decreased titre to 30 kDa antigen were observed with HLA-DR1-positive ATB patients than non-DR1 (ATB) patients. Moreover, HLA-DR4- and HLA-DR6-positive ATB patients showed trends toward an increased IgG antibody response to 30 kDa antigen than HLA-DR4- and HLADR6- negative (ATB) patients respectively. Significantly increased IgA antibody to 30 kDa antigen was observed with HLA-DR1-positive ATB patients than non-DR1 patients (P = 0.03). The study suggests that multiple HLA-DR molecules may regulate the IgG and IgA antibody responses to various proteins of M. tuberculosis. Moreover, HLA-DR phenotypes and increased IgG and IgA antibody titres may be useful to differentiate M. tuberculosis-infected subjects from normal subjects and cured patients with the same HLA-DR phenotypes or genetic make-up

Non-local properties of a symmetric two-qubit system

Non-local properties of symmetric two-qubit states are quantified in terms of a complete set of entanglement invariants. We prove that negative values of some of the invariants are signatures of quantum entanglement. This leads us to identify sufficient conditions for non-separability in terms of entanglement invariants. Non-local properties of two-qubit states extracted from (i) Dicke state (ii) state generated by one-axis twisting Hamiltonian, and (iii) one-dimensional Ising chain with nearest neighbour interaction are analyzed in terms of the invariants characterizing them.Comment: 5 pages, no figure

Non-classicality of photon added coherent and thermal radiations

Production and analysis of non-Gaussian radiation fields has evinced a lot of attention recently. Simplest way of generating such non-Gaussians is through adding (subtracting) photons to Gaussian fields. Interestingly, when photons are added to classical Gaussian fields, the resulting states exhibit {\em non-classicality}. Two important classical Gaussian radiation fields are coherent and thermal states. Here, we study the non-classical features of such states when photons are added to them. Non-classicality of these states shows up in the negativity of the Wigner function. We also work out the {\em entanglement potential}, a recently proposed measure of non-classicality for these states. Our analysis reveals that photon added coherent states are non-classical for all seed beam intensities; their non-classicality increases with the addition of more number of photons. Thermal state exhibits non-classicality at all temperatures, when a photon is added; lower the temperature, higher is their non-classicality.Comment: Version 2, minor revision; new references added, to appear in Eur. Phys. J. D, 6 pages, 10 figure ps files, RevTe