1 research outputs found
Synthesis of <span style="mso-fareast-language:EN-IN;mso-bidi-font-weight:bold" lang="EN-GB">chromene-2-thiones and <i style="mso-bidi-font-style:normal">in vitro</i> evaluation of their antifungal and antibacterial activities </span>
1224-1231Cyclocondensation of β-oxodithioesters with substituted 2-hydroxy
benzaldehydes in presence of copper(II)chloride as the catalyst yields 3-alkanoyl/aroyl/heteroaroyl-2H-chromene-2-thiones (87–95%
yields). These reactions are carried out under solvent-free conditions. All the
synthesized compounds have been evaluated for their antifungal and
antibacterial activities using tube dilution technique. Only five compounds are
found exhibiting good antifungal and antibacterial activities.
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